Modern materials contain extraordinary levels of complexity, with components spanning a hierarchy of length scales. Designing materials with complex microstructures and demonstrating unique behaviors would be difficult solely using a reductionist approach to materials development.   A powerful utility in this endeavor is using multiple, correlative, and scaffolding computational tools.  This talk focused on using an integrated materials design approach spanning electronic structure calculations to thermodynamics modeling and paired with combinatorial experimental methods to produce a high-temperature aluminum-based intermetallic for additive manufacturing.