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BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Penn Engineering Events - ECPv6.18.0//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-WR-CALNAME:Penn Engineering Events X-ORIGINAL-URL:https://seasevents.nmsdev7.com X-WR-CALDESC:Events for Penn Engineering Events REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:America/New_York BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20180311T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20181104T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20190310T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20191103T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20200308T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20201101T060000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=America/New_York:20191031T140000 DTEND;TZID=America/New_York:20191031T150000 DTSTAMP:20191017T133137Z CREATED:20191017T133137Z LAST-MODIFIED:20191017T133137Z UID:2150-1572530400-1572534000@seasevents.nmsdev7.com SUMMARY:MEAM Special Seminar: "Smartphone-based Mobile Detection Platform for Molecular Diagnostics: from Infectious Diseases to Cancer" DESCRIPTION:Rapid\, quantitative molecular diagnostics in the field\, at home\, and in resource poor settings is needed for evidence-based disease management\, control\, and prevention. Conventional molecular diagnostics requires extensive sample preparation\, sophisticated instruments\, and trained personnel\, restricting their use to centralized laboratories. To overcome the limitations of laboratory-based procedures\, we designed a simple\, inexpensive\, hand-held\, smartphone-based mobile detection platform “smart-connected cup”\, for rapid\, connected\, and quantitative detection of pathogens’ nucleic acids. More recently\, we have been expanding our technology platform to include detection of rare cancer biomarkers in body fluids for cancer screening and individualized therapy. To overcome the challenge of identifying very low concentrations of mutant alleles within a large background of very similar wild type nucleic acids\, we are using programmable enzymes to cleave wild type alleles and improve signal to noise ratio. We anticipate that our methods will improve quality of health care in regions lacking sophisticated laboratories and enable patients to assume greater responsibility for their care. URL:https://seasevents.nmsdev7.com/event/meam-special-seminar-smartphone-based-mobile-detection-platform-for-molecular-diagnostics-from-infectious-diseases-to-cancer/ LOCATION:Towne 227 (MEAM Conference Room)\, 220 S. 33rd Street\, Philadelphia\, PA\, 19104\, United States ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu END:VEVENT END:VCALENDAR