Programmable shape-shifting materials can take different physical forms to achieve multifunctionality in a dynamic and controllable manner. By introducing holes and cuts in 2D sheets, we demonstrate dramatic color and shape change and super-conformability via collapsing or expanding of the hole arrays in the micro- and macroscales. When choosing the cuts and geometry correctly, we show folding into the third dimension, known as kirigami. By programming the geometry of cuts and folding angles, we explore their potential applications in water harvesting, super-stretchable and shape conformable medical devices.