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DTSTART;TZID=America/New_York:20200218T110000
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DTSTAMP:20260408T012752
CREATED:20200207T164134Z
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UID:2637-1582023600-1582027200@seasevents.nmsdev7.com
SUMMARY:ESE Seminar: "Nanophotonics: A High Bandwidth Optical Neural Interface"
DESCRIPTION:Abstract\nLight is a powerful tool for interrogating and manipulating biological systems\, enabling targeted\nstimulation\, sensing\, and imaging. Optical methods such as optogenetics have transformed the study of\nneural circuits by making it possible to control neural activity using light. However\, there remains a critical\ndemand in research and medicine for miniaturized high resolution optical tools that can be embedded\ndeep within biological systems like the brain. The brain poses particular challenges due to the sheer\nnumber of densely packed interconnected neurons and the strong tissue scattering and absorption of\nlight. Nanophotonics\, or chip-scale optical circuits\, can enable unprecedented spatiotemporal resolution\nby leveraging nanoscale coherent control of a large set of optical channels within subwavelength\nwaveguides with high speed reconfiguration capability\, potential for integration with electronics\, and low-\ncost scalable manufacturability. This potential high bandwidth optical neural interface can be as thin as a\nfew neurons and have the ability to test spatial\, temporal\, and cell-type-specific aspects of neural\nencoding from cellular to system level within the brain. \nI will present the first implantable nanophotonic probe for optogenetic stimulation and recording of\nneurons in live mice. To achieve this\, we developed a reconfigurable visible nanophotonic platform based\non phase-controlled silicon nitride interferometric waveguide structures that can control cellular-sized\ncoherent emitters at blue wavelengths (peak of optogenetic actuators)\, far from traditional infrared\nwavelengths. This enabled a neural interface that can generate and read multi-neuron spike patterns\ndeep within the brain with single-cell and sub-millisecond resolution\, the highest resolution\nneuromodulation shown with an implantable probe. \nIn addition\, I will highlight two building blocks for future nanophotonic stimulation and sensing\ndevices that I developed using this platform: wide-angle chip-scale visible beam steering and multiplexing\nwithin a single waveguide by utilizing the transverse spatial degree-of-freedom of light. I will show how\nprecise phase control and novel nanoscale photonic design of these building blocks has been applied to\nemerging high bandwidth optical applications like portable display technology and quantum optical\nsystems. Finally\, I will present a future outlook towards a new generation of implantable and wearable\nbiomedical devices based on nanophotonic 3D light projection and sensing techniques including high-\ndimensional multiplexing\, volumetric beam shaping\, and quantum sensing.
URL:https://seasevents.nmsdev7.com/event/ese-seminar-nanophotonics-a-high-bandwidth-optical-neural-interface/
LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Colloquium
ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu
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