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DTSTAMP:20260601T194242
CREATED:20251113T155537Z
LAST-MODIFIED:20251113T155537Z
UID:15157-1763110800-1763118000@seasevents.nmsdev7.com
SUMMARY:ESE Ph.D. Thesis Defense: "Microfabricated devices for in-vivo sensing for mitochondrial assessment"
DESCRIPTION:Monitoring of oxygen concentration in biological tissues is essential for understanding cellular metabolism\, mitochondrial function\, and tissue regeneration. Mitochondrial dysfunction is linked to a wide range of metabolic and degenerative diseases\, yet current diagnostic approaches lack the capability to continuously measure oxygen and metabolite dynamics in vivo. This work introduces an implantable electrochemical sensor platform developed for real-time monitoring of tissue oxygen tension to support diagnosis and study of mitochondria-related disorders. The research encompasses device design\, fabrication\, preclinical validation\, and clinical testing within a translational framework. A complementary lactate sensor further extends the platform’s diagnostic capabilities\, establishing groundwork for future metabolic monitoring technologies.
URL:https://seasevents.nmsdev7.com/event/ese-ph-d-thesis-defense-microfabricated-devices-for-in-vivo-sensing-for-mitochondrial-assessment/
LOCATION:Room 221\, Singh Center for Nanotechnology\, 3205 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Dissertation or Thesis Defense
ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu
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