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DTSTART;TZID=America/New_York:20210324T150000
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SUMMARY:CBE Seminar: "Life in a Tight Spot: How Bacteria Move in Heterogeneous Media"
DESCRIPTION:Abstract \nBacterial motility is central to processes in agriculture\, the environment\, and medicine. While motility is typically studied in homogeneous environments\, many bacterial habitats—e.g.\, soils\, sediments\, and biological gels/tissues—are heterogeneous porous media. Here\, we use studies of E. coli in transparent 3D porous media to demonstrate how confinement in a heterogenous medium fundamentally alters motility. In particular\, we show how the paradigm of run-and-tumble motility is dramatically altered by pore-scale confinement\, both for cells performing undirected motion and those performing chemotaxis\, directed motion in response to a chemical stimulus. Our porous media also enable precisely structured multi-cellular communities to be 3D printed. Using this capability\, we show how spatial variations in the ability of cells to perform chemotaxis enable populations to autonomously stabilize large-scale perturbations in their overall morphology. Together\, our work thus reveals new principles to predict and control the behavior of bacteria\, and active matter in general\, in heterogeneous environments.
URL:https://seasevents.nmsdev7.com/event/cbe-seminar-life-in-a-tight-spot-how-bacteria-move-in-heterogeneous-media/
LOCATION:Zoom – Email CBE for link
CATEGORIES:Seminar
ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu
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