This seminar will be held virtually on Zoom. Check email for details or contact ksas@seas.upenn.edu.

Although much progress has been made in building artificial human tissues over the past several decades, replicating complex tissue structure remains an enormous challenge. To overcome this challenge, our field first needs to create better three-dimensional spatial maps, or “blueprints” of human tissues and organs. We also need to then understand how these spatial blueprints encode positional processes in tissues. My group is developing new advanced biofabrication technologies to address both of these issues. Here, I will describe some of our work in both attaining transcriptomic maps as well as in controlling spatiogenetic wiring of human artificial tissues.