This is a hybrid seminar: Check email for the zoom link and passcode.

“Cellular and Acellular Strategies for Heart and Lung Repair”

Therapeutic tissue regeneration using stem cells has been hampered by the controversial identity of resident stem cells, low cell retention/engraftment, tumorigenecity and immunogenicity issues. Taking a bioengineering/biomaterials approach, this lecture will introduce the uses of drug delivery and biomaterials strategies to generate more potent cell therapies for heart and lung diseases. In addition, a pharmacoengineering approach is taken to refine cell therapies by developing acelluar therapeutics such as stem cell-derived secretome and exosomes in the setting of heart and lung regeneration. This lecture will also mention a couple of stories in translating bench research into IND-enabled clinical trials on cell-based therapies.