Deprecated: TEC\Events_Pro\Custom_Tables\V1\WP_Query\Modifiers\Events_Not_Recurring_Custom_Tables_Query_Modifier::applies_to(): Implicitly marking parameter $query as nullable is deprecated, the explicit nullable type must be used instead in /home/seasevents/public_html/wp-content/plugins/events-calendar-pro/src/Events_Pro/Custom_Tables/V1/WP_Query/Modifiers/Events_Not_Recurring_Custom_Tables_Query_Modifier.php on line 61
Warning: Cannot modify header information - headers already sent by (output started at /home/seasevents/public_html/wp-content/plugins/events-calendar-pro/src/Events_Pro/Custom_Tables/V1/WP_Query/Modifiers/Events_Not_Recurring_Custom_Tables_Query_Modifier.php:61) in /home/seasevents/public_html/wp-content/plugins/the-events-calendar/src/Tribe/Views/V2/iCalendar/iCalendar_Handler.php on line 263
Warning: Cannot modify header information - headers already sent by (output started at /home/seasevents/public_html/wp-content/plugins/events-calendar-pro/src/Events_Pro/Custom_Tables/V1/WP_Query/Modifiers/Events_Not_Recurring_Custom_Tables_Query_Modifier.php:61) in /home/seasevents/public_html/wp-content/plugins/disable-xml-rpc-pingback/disable-xml-rpc-pingback.php on line 51
Warning: Cannot modify header information - headers already sent by (output started at /home/seasevents/public_html/wp-content/plugins/events-calendar-pro/src/Events_Pro/Custom_Tables/V1/WP_Query/Modifiers/Events_Not_Recurring_Custom_Tables_Query_Modifier.php:61) in /home/seasevents/public_html/wp-content/plugins/the-events-calendar/src/Tribe/iCal.php on line 511
Warning: Cannot modify header information - headers already sent by (output started at /home/seasevents/public_html/wp-content/plugins/events-calendar-pro/src/Events_Pro/Custom_Tables/V1/WP_Query/Modifiers/Events_Not_Recurring_Custom_Tables_Query_Modifier.php:61) in /home/seasevents/public_html/wp-content/plugins/the-events-calendar/src/Tribe/iCal.php on line 512
Warning: Cannot modify header information - headers already sent by (output started at /home/seasevents/public_html/wp-content/plugins/events-calendar-pro/src/Events_Pro/Custom_Tables/V1/WP_Query/Modifiers/Events_Not_Recurring_Custom_Tables_Query_Modifier.php:61) in /home/seasevents/public_html/wp-content/plugins/the-events-calendar/src/Tribe/iCal.php on line 515
BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Penn Engineering Events - ECPv6.18.0//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Penn Engineering Events
X-ORIGINAL-URL:https://seasevents.nmsdev7.com
X-WR-CALDESC:Events for Penn Engineering Events
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:America/New_York
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20200308T070000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20201101T060000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20210314T070000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20211107T060000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20220313T070000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20221106T060000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210211T150000
DTEND;TZID=America/New_York:20210211T160000
DTSTAMP:20210112T135214Z
CREATED:20210112T135214Z
LAST-MODIFIED:20210112T135214Z
UID:3828-1613055600-1613059200@seasevents.nmsdev7.com
SUMMARY:BE Seminar: "Multi-input Chemical Control With Computationally Designed Proteins for Research Tools and Cell Therapies" (Glenna Wink Foight)
DESCRIPTION:This event will be held virtually via Zoom – check email for details or contact ksas@seas.upenn.edu \nProtein modules that are responsive to small molecule inputs have enabled control of cellular processes for decades’ worth of important mechanistic studies. More recently\, they have gained attention as a means of control for improved safety of cellular therapies. To date\, most small molecule-responsive systems have been adapted from natural proteins\, which provide limited control behaviors and often rely on small molecules with non-ideal properties for use in humans. I will describe how we have used computational protein design to move beyond these naturally occurring systems to create a new set of molecular tools that are responsive to multiple clinically approved drugs. The unique architecture of our system enables more complex control behaviors for multiple cellular outputs. I will describe applications of this designed system in the control of mammalian cytoskeletal signaling\, transcription\, and CAR T-cell therapy. \n
URL:https://seasevents.nmsdev7.com/event/be-seminar-glenna-wink-foight/
CATEGORIES:Seminar
ORGANIZER;CN="Bioengineering":MAILTO:be@seas.upenn.edu
END:VEVENT
END:VCALENDAR