BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Penn Engineering Events - ECPv6.15.18//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Penn Engineering Events
X-ORIGINAL-URL:https://seasevents.nmsdev7.com
X-WR-CALDESC:Events for Penn Engineering Events
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:America/New_York
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20190310T070000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20191103T060000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20200308T070000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20201101T060000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20210314T070000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20211107T060000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201119T150000
DTEND;TZID=America/New_York:20201119T160000
DTSTAMP:20260407T092046
CREATED:20200709T143802Z
LAST-MODIFIED:20200709T143802Z
UID:3141-1605798000-1605801600@seasevents.nmsdev7.com
SUMMARY:BE Seminar: "Emerging Technologies for Detection of Early Stage Bladder Cancer" (Audrey Bowden)
DESCRIPTION:This event will held virtually on zoom. Check email for the link or contact ksas@seas.upenn.edu. \nBladder cancer (BC) —  the 4th most common cancer in men and the most expensive cancer to treat over a patient’s lifetime — is a lifelong burden to BC patients and a significant economic burden to the U.S. healthcare system. The high cost of BC stems largely from its high recurrence rate (>50%); hence\, BC management involves frequent surveillance. Unfortunately\, the current in-office standard-of-care tool for BC surveillance\, white light cystoscopy (WLC)\, is limited by low sensitivity and specificity for carcinoma in situ (CIS)\, a high-grade carcinoma with high potential to metastasize. Early detection and complete eradication of CIS are critical to improve treatment outcomes and to minimize recurrence. The most promising macroscopic technique to improve sensitivity to CIS detection\, blue light cystoscopy (BLC)\, is costly\, time-intensive\, has low availability and a high false-positive rate. Given the limitations of WLC\, we aim to change the paradigm around how BC surveillance is performed by validating new tools with high sensitivity and specificity for CIS that are appropriate for in-office use. In this seminar\, I discuss our innovative solutions to improve mapping the bladder for longitudinal tracking of suspicious lesions and to create miniature tools for optical detection based on optical coherence tomography (OCT). OCT and its functional variant\, cross-polarized OCT\, can detect early-stage BC with better sensitivity and specificity than WLC. We discuss the critical technical innovations necessary to make OCT and CP-OCT a practical tool for in-office use\, and new results from recent explorations of human bladder samples that speak to the promise of this approach to change the management of patient care.
URL:https://seasevents.nmsdev7.com/event/be-seminar-4/
CATEGORIES:Seminar
ORGANIZER;CN="Bioengineering":MAILTO:be@seas.upenn.edu
END:VEVENT
END:VCALENDAR