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DTSTART;TZID=America/New_York:20231017T100000
DTEND;TZID=America/New_York:20231017T113000
DTSTAMP:20260404T033828
CREATED:20231002T152507Z
LAST-MODIFIED:20231002T152507Z
UID:10007718-1697536800-1697542200@seasevents.nmsdev7.com
SUMMARY:MEAM Seminar: "A Symbiotic Philosophy for Bio-inspired Robotics"
DESCRIPTION:Humans have frequently looked to natural phenomena to inspire the design of art\, structures\, and mechanisms. However\, there are as many different ways to learn from nature as there are words for this approach: bioinspiration\, biomimicry\, and biodesign to name a few. In this talk\, I propose a taxonomy for categorizing distinct biodesign approaches and use examples from my own research to illustrate the methodology and benefits of each. In particular\, I introduce the field of Animal-Robot Interactions and describe how bio-inspired approaches can be used to further biological inquiry while advancing robotics.
URL:https://seasevents.nmsdev7.com/event/meam-seminar-a-symbiotic-philosophy-for-bio-inspired-robotics/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20231017T133000
DTEND;TZID=America/New_York:20231017T143000
DTSTAMP:20260404T033828
CREATED:20231013T221142Z
LAST-MODIFIED:20231013T221142Z
UID:10007728-1697549400-1697553000@seasevents.nmsdev7.com
SUMMARY:Fall 2023 GRASP Seminar: Donglai Xiang\, Carnegie Mellon University\, "Modeling Dynamic Clothing for Data-Driven Photorealistic Avatars"
DESCRIPTION:This is a hybrid event with in-person attendance in Levine 512 and virtual attendance on Zoom. \nABSTRACT\nIn this talk\, I will present research on building photorealistic avatars of humans wearing complex clothing in a data-driven manner. Such avatars will be a critical technology to enable future applications such as VR/AR and virtual content creation. Loose-fitting clothing poses a significant challenge for avatar modeling due to its large deformation space. We address the challenge by unifying three components of avatar modeling: model-based statistical prior from pre-captured data\, physics-based prior from simulation\, and real-time measurement from sparse sensor input. First\, we introduce a separate two-layer representation that allows us to disentangle the dynamics between the pose-driven body part and temporally-dependent clothing part. Second\, we further combine physics-based cloth simulation with a physics-inspired neural rendering model to generate rich and natural dynamics and appearance even for challenging clothing such as a skirt and a dress. Last\, we go beyond pose-driven animation and incorporate online sensor input into the avatars to achieve more faithful telepresence of clothing.
URL:https://seasevents.nmsdev7.com/event/fall-2023-grasp-seminar-donglai-xiang-carnegie-mellon-university-modeling-dynamic-clothing-for-data-driven-photorealistic-avatars/
LOCATION:Levine 512
CATEGORIES:Seminar
ORGANIZER;CN="General Robotics%2C Automation%2C Sensing and Perception (GRASP) Lab":MAILTO:grasplab@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20231017T153000
DTEND;TZID=America/New_York:20231017T163000
DTSTAMP:20260404T033828
CREATED:20231004T190116Z
LAST-MODIFIED:20231004T190116Z
UID:10007722-1697556600-1697560200@seasevents.nmsdev7.com
SUMMARY:CIS Seminar: "Reliable Quantum Computing Needs Intelligent Software and Hardware"
DESCRIPTION:Quantum computers can solve important problems that are beyond the capability of conventional computers. Quantum computing is at an inflection point where small systems with a few tens qubits have been demonstrated and the number of qubits is expected to increase to several thousand over the coming years. As qubits are low-energy devices\, they are susceptible to high error-rates (in the range of 0.1% to 1% per operation). Unfortunately\, quantum error-correction incurs a significant overhead (hundreds of physical qubits per fault-tolerant qubit) and is impractical for near-term machines. Therefore\, hardware errors will continue to severely restrict the length of the program that can be reliably executed on a near-term quantum computer. In this talk\, I will offer a computer-systems perspective of quantum computers and then share some of our recent work that improves the reliability of near-term quantum computers with intelligent software techniques. I will also discuss the hardware support necessary to enable large- scale quantum computers.
URL:https://seasevents.nmsdev7.com/event/cis-seminar-reliable-quantum-computing-needs-intelligent-software-and-hardware/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Colloquium
ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20231018T120000
DTEND;TZID=America/New_York:20231018T131500
DTSTAMP:20260404T033828
CREATED:20230908T195846Z
LAST-MODIFIED:20230908T195846Z
UID:10007679-1697630400-1697634900@seasevents.nmsdev7.com
SUMMARY:Engineering Faculty Teaching Forum: "Awake & Engaged: Making Lectures More Interactive"
DESCRIPTION:Lectures can be a useful method for communicating complex information but are most effective when students are engaged with and focused on the material. Drs. Igor Bargatin and Amish Patel will start this informal conversation by sharing their strategies for making lectures more interactive. We’ll consider ways to increase student attention and interaction to promote deeper learning. Lunch will be provided for those who register in advance<https://ctl.upenn.edu/event/awake-engaged-making-lectures-more-interactive/>.
URL:https://seasevents.nmsdev7.com/event/engineering-faculty-teaching-forum-awake-engaged-making-lectures-more-interactive/
LOCATION:Towne 108\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Faculty
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20231018T120000
DTEND;TZID=America/New_York:20231018T131500
DTSTAMP:20260404T033828
CREATED:20230928T141146Z
LAST-MODIFIED:20230928T141146Z
UID:10007705-1697630400-1697634900@seasevents.nmsdev7.com
SUMMARY:ASSET Seminar: "Lifelong Learning for Autonomous Systems: Progress and Challenges" (Eric Eaton\, Penn)
DESCRIPTION:ABSTRACT:  \nResearch in lifelong or continual machine learning has advanced rapidly over the past few years\, primarily focusing on enabling learned models to acquire new tasks over time while avoiding catastrophic forgetting of previous tasks. However\, autonomous systems still lack the ability to rapidly learn new generalizable skills by building upon and continually refining their learned knowledge—a hallmark of lifelong learning in humans and animals. In this talk\, I will examine our progress toward lifelong machine learning and its application to autonomous systems\, exploring recent work in compositional representations and self-supervision. We’ll then discuss how far we have come and the open problems that remain toward learning generalizable skills in lifelong settings.
URL:https://seasevents.nmsdev7.com/event/asset-seminar-eric-eaton-penn/
LOCATION:Levine 307\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20231018T153000
DTEND;TZID=America/New_York:20231018T163000
DTSTAMP:20260404T033828
CREATED:20230830T170153Z
LAST-MODIFIED:20230830T170153Z
UID:10007661-1697643000-1697646600@seasevents.nmsdev7.com
SUMMARY:CBE Seminar: "Energetic Constraints on Biological Assembly and Motion" (Murrell\, Yale)
DESCRIPTION:On small length-scales\, the mechanics of soft materials may be dominated by their interfacial properties as opposed to their bulk properties. These effects are described by equilibrium models of elasto-capillarity and wetting. In these models\, interfacial energies and bulk material properties are held constant. However\, in biological materials\, including living cells and tissues\, these properties are not constant\, but are ‘actively’ regulated and driven far from thermodynamic equilibrium. As a result\, the constraints on work produced during the various physical behaviors of the cell are unknown. Here\, by measurement of elasto-capillary effects during cell adhesion\, growth and motion\, we demonstrate that interfacial and bulk parameters violate equilibrium constraints and exhibit anomalous effects\, which depend upon a distance from equilibrium. However\, their anomalous properties are reciprocal\, and thus in combination reliably define energetic constraints on the production of work arbitrarily far from equilibrium. These results provide basic principles that govern biological assembly and behavior.
URL:https://seasevents.nmsdev7.com/event/cbe-seminar-energetic-constraints-on-biological-assembly-and-motion-murrell-yale/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20231019T103000
DTEND;TZID=America/New_York:20231019T120000
DTSTAMP:20260404T033828
CREATED:20230831T185735Z
LAST-MODIFIED:20230831T185735Z
UID:10007664-1697711400-1697716800@seasevents.nmsdev7.com
SUMMARY:MSE Seminar: "Bioinspired Polymers for Tissue Repair and Regeneration" (Phillip B. Messersmith University of California - Berkeley)
DESCRIPTION:It is of great interest for materials scientists to study wet biological adhesives as inspiration for synthetic adhesives that can perform well in wet conditions. A compelling example is given by the adhesive proteins secreted by marine mussels\, which have inspired the development of synthetic polymer adhesives and coatings for adhesion to wet surfaces. Mussel byssal proteins contain high levels of the amino acid 3\,4-dihydroxy-L-alanine (DOPA)\, which has a catechol functional group that is believed to contribute to both the interfacial adhesive and bulk mechanical performance of the tissue. In this talk\, I will review what is known about the function of DOPA in the mussel byssus and describe our ongoing efforts focused on exploiting catechol-containing polymers to solve practical problems in wet adhesion. Emphasis will be placed on bioinspired adhesives\, hydrogels and coatings for tissue repair. Recently\, we have begun to combine bioinspired tissue adhesives with a releasable pro-regenerative drug that pharmacologically upregulates the transcription factor hypoxia-inducible factor 1 alpha (HIF-1α) to enhance tissue regeneration in mammals. Our early in-vivo results suggest that combining bioinspired tissue adhesives with drug-induced regeneration can produce remarkable results in clinical situations where both tissue repair and regeneration are desired.
URL:https://seasevents.nmsdev7.com/event/mse-seminar-bioinspired-polymers-for-tissue-repair-and-regeneration-university-of-california-berkeley/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="Materials Science and Engineering":MAILTO:johnruss@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20231019T120000
DTEND;TZID=America/New_York:20231019T140000
DTSTAMP:20260404T033828
CREATED:20231016T124015Z
LAST-MODIFIED:20231016T124015Z
UID:10007731-1697716800-1697724000@seasevents.nmsdev7.com
SUMMARY:ESE PhD Thesis Defense: "CyberCardia: Patient-specific Electrophysiological heart model for assisting left atrium arrhythmia ablation"
DESCRIPTION:Atrial arrhythmia is a prevalent heart disease that results in weak and irregular contractions of the atria. It affects millions of people worldwide. Cardiac ablation is among the most successful treatment options. During the procedure\, catheters are inserted into the left atrium to map the atrium geometry and record endocardium electrograms that are then converted into electroanatomical maps to pinpoint the arrhythmia source locations. \nHowever\, identifying arrhythmia sources is challenging. The electrograms are asynchronous and can be susceptible to noise. The spatial distribution of sampling sites is non-uniform\, which leads to inaccurate maps. Identifying arrhythmia source locations is not a trivial task. Therefore\, an ablation procedure often lasts from 3 to 6 hours\, and arrhythmia recurrence within 12 months after first ablation is about 45%. \nTo address these challenges\, we developed an integrated computational heart model to guide left atrium arrhythmia ablation. Our system takes in the left atrium geometry and electrograms\, processes them to extract regional tissue properties\, which are used to tune a heart model\, creating a patient-specific whole-atrium model. With this model\, we can simulate and detect arrhythmia sources\, and provide ablation assistance. To build such a system\, we investigated the fiber effects on atrial activation patterns. We developed a fast heart model tuning method which takes only a few seconds of computation time on a personal computer\, enabling real-time assistance during the ablation procedure. We achieved high accuracy in simulating arrhythmias\, which we validated on patient data.
URL:https://seasevents.nmsdev7.com/event/ese-phd-thesis-defense-cybercardia-patient-specific-electrophysiological-heart-model-for-assisting-left-atrium-arrhythmia-ablation/
LOCATION:Room 313\, Singh Center for Nanotechnology\, 3205 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Dissertation or Thesis Defense
ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20231019T153000
DTEND;TZID=America/New_York:20231019T163000
DTSTAMP:20260404T033828
CREATED:20230807T142040Z
LAST-MODIFIED:20230807T142040Z
UID:10007623-1697729400-1697733000@seasevents.nmsdev7.com
SUMMARY:BE Seminar: "Robust CRISPR/Cas-based epigenome editing technologies for precision human cell engineering and mechanistic dissection of pathological gene expression" (Isaac Hilton\, Rice University)
DESCRIPTION:Recent advances in CRISPR/Cas-based epigenome editing technologies have enabled programmable control over human gene expression\, chromatin states\, and genomic organization. Consequently\, these emerging technologies have created new opportunities to engineer human cells for therapeutic benefit and catalyzed innovative ways to functionally interrogate gene regulatory mechanisms in situ. Toward these ends\, we have recently developed new capabilities in the context of CRISPR/Cas-based transcriptional activation (CRISPRa) modalities. First\, we have identified and repurposed key segments from natural human transcription factors to build potent and compact multipartite transactivation modules and in turn build the CRISPR-DREAM platform. CRISPR-DREAM is specific\, robust across mammalian cell types\, efficacious at diverse human regulatory elements\, and well tolerated in therapeutically important primary cells – including T cells\, MSCs\, neurons\, and iPSCs. We have also leveraged the small size and potency of CRISPR-DREAM components to generate all-in-one CRISPRa AAV systems that expand opportunities for in vivo gene control. Second\, in unpublished studies\, we have isolated intrinsically disordered regions (IDRs) from oncogenic fusion proteins associated with therapeutically intractable hematologic malignancies and nuclear phase separation. We find that different IDR compositions exhibit distinct propensities for nuclear import and biomolecular condensation in human cell nuclei. We demonstrate using precision CRISPR-based targeting of IDRs to human loci\, that levels of phase separation can be directly proportional to target gene activation. Interestingly we also find that while core transcriptomic network changes are shared among certain oncogenic IDR fusion proteins\, phase separation behaviors and genomic engagement occur in discrete ways – suggesting divergent IDR-driven routes to cellular oncogenesis\, the control over which could create new possibilities for tailored therapeutic approaches.
URL:https://seasevents.nmsdev7.com/event/be-seminar-robust-crispr-cas-based-epigenome-editing-technologies-for-precision-human-cell-engineering-and-mechanistic-dissection-of-pathological-gene-expression-isaac-hilton-rice-university/
LOCATION:216 Moore Building
CATEGORIES:Seminar
ORGANIZER;CN="Bioengineering":MAILTO:be@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20231020T100000
DTEND;TZID=America/New_York:20231020T110000
DTSTAMP:20260404T033828
CREATED:20231012T001331Z
LAST-MODIFIED:20231012T001331Z
UID:10007725-1697796000-1697799600@seasevents.nmsdev7.com
SUMMARY:PRECISE Seminar: "Co-Optimizing Imaging\, Computer Systems\, and Biological Perception for Next-Generation Visual Computing Platforms"
DESCRIPTION:Abstract \nEmerging platforms such as Augmented Reality (AR)\, Virtual Reality (VR)\, and autonomous machines\, while are of a computing nature\, intimately interact with both the environment and humans. They must be built\, from the ground up\, with principled considerations of three main components: imaging\, computer systems\, and human perception. This talk will make a case for this tenet and discuss some of our recent work on this front. \nI will first talk about in-sensor visual computing\, the idea that co-designing the image sensor with the computer systems will significantly improve the overall system efficiency and\, perhaps more importantly\, unlock new machine capabilities. We will show a number of case studies in AR/VR and autonomous machines. I will then discuss our work on human-systems co-optimizations\, where we computationally model biological (human) vision to build energy-efficient AR/VR devices without degrading\, sometimes even enhancing\, human perception. \nIf time permits\, I will briefly discuss how we build fast and robust computing systems for autonomous machines\, many of which are now deployed by a self-driving car start-up.
URL:https://seasevents.nmsdev7.com/event/precise-seminar-co-optimizing-imaging-computer-systems-and-biological-perception-for-next-generation-visual-computing-platforms/
LOCATION:Levine 307\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
ORGANIZER;CN="PRECISE":MAILTO:wng@cis.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20231020T103000
DTEND;TZID=America/New_York:20231020T114500
DTSTAMP:20260404T033828
CREATED:20230728T145630Z
LAST-MODIFIED:20230728T145630Z
UID:10007616-1697797800-1697802300@seasevents.nmsdev7.com
SUMMARY:Fall 2023 GRASP on Robotics: Leslie Kaelbling\, Massachusetts Institute of Technology\, "Doing for our robots what nature did for us"
DESCRIPTION:This is a hybrid event with in-person attendance in Wu and Chen and virtual attendance on Zoom. \nABSTRACT\nWe\, as robot engineers\, have to think hard about our role in the design of robots and how it interacts with learning\, both in “the factory” (that is\, at engineering time) and in “the wild” (that is\, when the robot is delivered to a customer). I will share some general thoughts about strategies for robot software design that combine machine learning with insights from natural intelligence and from classical engineering design. I will describe several research projects\, both in the design of an overall architecture for an intelligent robot and in strategies for learning to integrate new skills into the repertoire of an already competent robot.
URL:https://seasevents.nmsdev7.com/event/fall-2023-grasp-on-robotics-leslie-kaelbling-massachusetts-institute-of-technology-doing-for-our-robots-what-nature-did-for-us/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="General Robotics%2C Automation%2C Sensing and Perception (GRASP) Lab":MAILTO:grasplab@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20231020T130000
DTEND;TZID=America/New_York:20231020T150000
DTSTAMP:20260404T033828
CREATED:20231011T125444Z
LAST-MODIFIED:20231011T125444Z
UID:10007724-1697806800-1697814000@seasevents.nmsdev7.com
SUMMARY:BE Doctoral Dissertation Defense: "Uncovering Structure-function Relationships in Chromatin Architecture" (Daniel Emerson)
DESCRIPTION:The Department of Bioengineering at the University of Pennsylvania and Dr. Jennifer Phillips-Cremins are pleased to announce the Doctoral Dissertation Defense of Daniel Emerson.\n \nTitle: Uncovering Structure-function Relationships in Chromatin Architecture\n\n \nDate: October 20\, 2023\nTime: 1:00 PM\nLocation: BRB 0253\n\nZoom link\n\n\n\nThe Public is welcome to attend.
URL:https://seasevents.nmsdev7.com/event/be-doctoral-dissertation-defense-uncovering-structure-function-relationships-in-chromatin-architecture-daniel-emerson/
LOCATION:BRB 253
CATEGORIES:Doctoral,Graduate,Student,Dissertation or Thesis Defense
ORGANIZER;CN="Bioengineering":MAILTO:be@seas.upenn.edu
END:VEVENT
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