BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Penn Engineering Events - ECPv6.15.18//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-WR-CALNAME:Penn Engineering Events X-ORIGINAL-URL:https://seasevents.nmsdev7.com X-WR-CALDESC:Events for Penn Engineering Events REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:America/New_York BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20220313T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20221106T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20230312T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20231105T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20240310T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20241103T060000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=America/New_York:20230213T130000 DTEND;TZID=America/New_York:20230213T140000 DTSTAMP:20260405T015106 CREATED:20230111T150248Z LAST-MODIFIED:20230111T150248Z UID:10007420-1676293200-1676296800@seasevents.nmsdev7.com SUMMARY:PSOC Seminar: "Multidimensional immunoengineering approaches to enhanced cancer immunotherapy" (Li Tang\, EPFL) DESCRIPTION:Spring 2023 Hybrid-Seminar Series\nMondays 1.00-2.00 pm (EST)\nTowne 225 / Raisler Lounge\n“For Zoom link\, please contact ” URL:https://seasevents.nmsdev7.com/event/psoc-seminar-overcoming-a-mechanical-immune-checkpoint-for-enhanced-cancer-immunotherapy-li-tang-epfl/ LOCATION:Raisler Lounge (Room 225)\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="PSOC":MAILTO:manu@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20230214T100000 DTEND;TZID=America/New_York:20230214T113000 DTSTAMP:20260405T015106 CREATED:20230204T202403Z LAST-MODIFIED:20230204T202403Z UID:10007455-1676368800-1676374200@seasevents.nmsdev7.com SUMMARY:MEAM Seminar: "Data-Aware Computational Models for Science and Engineering" DESCRIPTION:In the past half-century\, partial differential equation (PDE)-based computational models have emerged as indispensable for science and engineering. However\, remarkable gaps still exist between state-of-the-art simulations and reality\, meaning that many simulations are ineffective in supporting decision-making or design under uncertainty for complex systems (e.g.\, Mars landing). To bridge the gap and fulfill challenging real-world missions\, I develop data-aware computational models that combine increasingly available data with complex PDE-based models to make improved predictions\, together with measures of their uncertainty. \nIn this talk\, I will focus on two complementary approaches to data-aware computational modeling. First\, I will discuss a new Bayesian method for updating/improving computational models and quantifying uncertainties based on measured data: our Kalman inversion approach is built on Kalman filtering and empirically converges in O(10) iterations with O(10) ensemble evaluations per iteration\, enabling effective Bayesian calibration with very few model evaluations. Second\, I will introduce our geometry-aware Fourier neural operator (FNO)\, a deep learning surrogate model which maps a given design geometry to a predicted PDE solution state. We use the automatic differentiation tools of deep learning packages to efficiently compute gradients of the FNO approximation\, enabling real-time multiphysics engineering design optimization. These methods we developed have been successfully applied in complex applications ranging from Mars landing supersonic parachute\, bacteria-resistant catheter design\, the digital twin for airfoil damage detection\, and the Earth system model for climate science. URL:https://seasevents.nmsdev7.com/event/meam-seminar-data-aware-computational-models-for-science-and-engineering/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20230214T153000 DTEND;TZID=America/New_York:20230214T163000 DTSTAMP:20260405T015106 CREATED:20230206T163936Z LAST-MODIFIED:20230206T163936Z UID:10007464-1676388600-1676392200@seasevents.nmsdev7.com SUMMARY:CIS Seminar: "Rethinking System Design for Expressive Cryptography" DESCRIPTION:Expressive cryptography\, including Secure Multi-Party Computation (SMPC) and Fully Homomorphic Encryption (FHE)\, has the potential to enable transformative new applications\, drawing significant interest from industry. Unfortunately\, it is often slow and resource-intensive\, making those applications difficult to realize. For example\, SMPC enables multiple organizations (e.g.\, hospitals) to run joint computations on their data (e.g.\, for better medical diagnosis and treatment) while keeping the inputs to the computation (e.g.\, patient data) secret. But SMPC can have high memory overhead\, making it difficult to scale such applications to large problem sizes. \nThis talk demonstrates how we can design and build systems to enable expressive cryptography to reach its full transformative potential. For example\, my system MAGE provides virtual memory for SMPC and FHE at nearly zero cost\, allowing them to efficiently scale beyond the system’s available memory. My work in this area also includes JEDI\, which shows how IoT devices can use expressive cryptography efficiently\, and TCPlp\, which was recently adopted in OpenThread\, an open-source network stack used in the smart home industry. By rethinking system design for expressive cryptography\, we can bring stronger security to existing applications and enable exciting new ones. URL:https://seasevents.nmsdev7.com/event/cis-seminar-rethinking-system-design-for-expressive-cryptography/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20230215T120000 DTEND;TZID=America/New_York:20230215T133000 DTSTAMP:20260405T015106 CREATED:20230104T183109Z LAST-MODIFIED:20230104T183109Z UID:10007400-1676462400-1676467800@seasevents.nmsdev7.com SUMMARY:ASSET Seminar: Decision-Aware Learning for Global Health Supply Chains\, Osbert Bastani (University of Pennsylvania) DESCRIPTION:Abstract: \nMachine learning algorithms are increasingly used in conjunction with optimization to guide decision making. A key challenge is aligning the machine learning loss with the decision-making loss. Existing solutions have limited flexibility and/or scale poorly to large datasets. We propose a principled decision-aware learning algorithm that uses a Taylor expansion of the optimal decision loss to derive the machine learning loss. Importantly\, our approach only requires a simple re-weighting of the training data\, allowing it to easily and scalably be incorporated into complex modern data science pipelines while producing sizable efficiency gains. We apply our framework to optimize the distribution of essential medicines in Sierra Leone in collaboration with their National Medical Supplies Agency. Out-of-sample results demonstrate that our end-to-end approach significantly reduces unmet demand across 1000+ health facilities throughout Sierra Leone. URL:https://seasevents.nmsdev7.com/event/asset-seminar-decision-aware-learning-for-global-health-supply-chains-osbert-bastani-university-of-pennsylvania/ LOCATION:Levine 307\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20230215T133000 DTEND;TZID=America/New_York:20230215T143000 DTSTAMP:20260405T015106 CREATED:20230206T183548Z LAST-MODIFIED:20230206T183548Z UID:10007465-1676467800-1676471400@seasevents.nmsdev7.com SUMMARY:CIS Seminar: "Methods of Data Lookup with Hashing" DESCRIPTION:We will discuss methods of data lookup\, with a focus on hash sets / tables\, including motivation\, properties\, and variants. This will be in the context of a “CS 2” or data structures course. We will assume a basic familiarity with programming and comfort with implementing resizable lists; as well as knowledge of (but not necessarily comfort with) asymptotic analysis. URL:https://seasevents.nmsdev7.com/event/cis-seminar-methods-of-data-lookup-with-hashing/ LOCATION:Levine 307\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20230215T153000 DTEND;TZID=America/New_York:20230215T163000 DTSTAMP:20260405T015106 CREATED:20230206T140952Z LAST-MODIFIED:20230206T140952Z UID:10007456-1676475000-1676478600@seasevents.nmsdev7.com SUMMARY:CBE Seminar Series: "A New Phase of Biological Controls: A Design Framework for Programmable Synthetic Biomolecular Condensates and the Mechanisms of a Functional Liquid-Liquid Interface" (Yifan Dai\, Duke University) DESCRIPTION:Abstract: \nA fundamental question in nature is how the cellular processes are organized with sequential and spatial precision in a dynamic and densely packed environment. Evidence is now mounting that biomolecular condensation\, a demixing process mediated by phase separation coupled with percolation\, dictates the organization principles of cellular biochemistry. From the perspective of synthetic biology\, programmable condensation in living cells represents a new fundamental capability for biological design\, going beyond the current engineering capability of lock-and-key interactions. In the first part of the talk\, I will introduce a rational design strategy of synthetic intrinsically disordered proteins toward functional synthetic biomolecular condensates for cellular controls in bacteria and human cells. I will demonstrate the applications of synthetic condensates on four distinct cellular processes: cell division\, transcription\, translation\, and modulation of protein circuits\, providing a toolbox for orthogonal central dogma. \nIn the second part of the talk\, I will dig into the physical chemistry principles of condensate microenvironments\, by which condensates can encode unique electrochemical features at its liquid-liquid interface. I will introduce a theoretical framework we developed for condensate interface\, which allows us to understand the density transition process of condensate formation from the perspective of electrochemistry. I will then discuss our experimental discoveries on the fundamental electrochemical properties of liquid-liquid interface and how these features can regulate cellular processes. These discoveries open new directions of condensate research and provide answers for many previously unexplained biological activities of biomolecular condensates. \nOverall\, the first work has established a design principle for programmable condensation as a new capability of synthetic biology. The second work combining insights from physical chemistry\, electrochemistry and cell biology has delivered a new paradigm for understanding how condensates can engender cellular functions through its chemical environments and liquid-liquid interface. \nBio: \nYifan Dai is a postdoc associate at the Department of Biomedical Engineering at Duke University\, co-advised by Professor Ashutosh Chilkoti and Professor Lingchong You. He obtained his B.S. and Ph.D. in 2017 and 2020 both in Chemical and Biomolecular Engineering from Case Western Reserve University. Since his undergraduate\, he had worked on engineering strategies to integrate synthetic biology with electrochemistry to enable translation of biological signals into electricity for biosensing applications\, which have led to multiple licensed technologies. In his postdoc\, he has worked on 1) uncovering the principles of biomolecular phase transitions for engineering biology and 2) establishing the theoretical framework of condensate microenvironments and liquid-liquid interface. URL:https://seasevents.nmsdev7.com/event/cbe-seminar-series-a-new-phase-of-biological-controls-a-design-framework-for-programmable-synthetic-biomolecular-condensates-and-the-mechanisms-of-a-functional-liquid-liquid-interface-yifan-dai/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20230216T140000 DTEND;TZID=America/New_York:20230216T160000 DTSTAMP:20260405T015106 CREATED:20230213T201930Z LAST-MODIFIED:20230213T201930Z UID:10007475-1676556000-1676563200@seasevents.nmsdev7.com SUMMARY:ESE PhD Thesis Defense: "Accelerating FPGA Developments from C to Bitstreams by Partial Reconfiguration" DESCRIPTION:Divide-and-Conquer and incremental compilation strategies are widely used in software compilations. To enable these strategies for FPGAs\, this dissertation presents an open-source framework called PRflow\, which can speed up the compilation times by at most an order of magnitude. PRflow supports different optimization levels to make better trade-offs among compile-time\, area\, and performance. -O0 (PRflow_RISCV) maps applications to a cluster of on-chip RISC-V cores within seconds for quick verification and debugging. -O1 (PRflow) compiles the separate parts of an application to partial FPGA bitstreams for different Partial reconfigurable regions on the chip. Individual parts can be compiled in parallel within 24 minutes. The interconnections between separate parts can be recompiled by configuring the NoC by sending configuration packets by the host. -O2 (PRflow_DW) supports inter-connection customization with a fixed page-size overlay on top of commercial FPGA to meet high inter-page bandwidth requirements which can improve the performance by up to 10X compared with -O1. -O3 (PRflow_HiPR) supports overlay customization for higher inter-page throughput and various size requirements with similar incremental compile time to -O1 and -O2. This dissertation demonstrates the PRflow framework on the Xilinx Alveo-U50 data-center card with an xcu50-fsvh2104-2-e FPGA chip (14nm FinFET) by mapping Rosetta HLS complete benchmark set. PRflow can accelerate the compilation times from 2–3 hours (state-of-art Vitis) to 10-24 minutes. URL:https://seasevents.nmsdev7.com/event/ese-phd-thesis-defense-accelerating-fpga-developments-from-c-to-bitstreams-by-partial-reconfiguration/ LOCATION:Cora Ingrum Conference Room (Towne 215 – enter at Towne 211) CATEGORIES:Dissertation or Thesis Defense ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20230216T153000 DTEND;TZID=America/New_York:20230216T163000 DTSTAMP:20260405T015106 CREATED:20230105T171916Z LAST-MODIFIED:20230105T171916Z UID:10007410-1676561400-1676565000@seasevents.nmsdev7.com SUMMARY:BE Seminar: "Programming multicellular interactions and organization using synthetic cell adhesion molecules" (Adam Stevens\, UCSF) DESCRIPTION:Cell adhesion molecules (CAMs) are ubiquitous in multicellular organisms and specify precise cellular interactions in processes as diverse as tissue development and immune cell trafficking. We have generated an array of synthetic CAMs by combining orthogonal extracellular interactions with native intracellular domains. Diverse homotypic or heterotypic extracellular binding domains specify the connectivity between cells\, while the intracellular domain identity dictates interface morphology and mechanics. This approach highlights CAM modularity and enables rationally programmed assembly and remodeling of multicellular architectures. Overall\, these tools offer new customizable capabilities for cell and tissue engineering and for systematically studying multicellular organization. URL:https://seasevents.nmsdev7.com/event/be-seminars-adams-stevens-ucsf/ LOCATION:Glandt Forum\, Singh Center for Nanotechnology\, 3205 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar,Postdoctoral ORGANIZER;CN="Bioengineering":MAILTO:be@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20230216T153000 DTEND;TZID=America/New_York:20230216T163000 DTSTAMP:20260405T015106 CREATED:20230206T191346Z LAST-MODIFIED:20230206T191346Z UID:10007466-1676561400-1676565000@seasevents.nmsdev7.com SUMMARY:CIS Seminar: "Birds of a Feather Flock Together: How Homophily Leads to Segregation\, Inequality\, and Inefficiency and What We Can Do About It" DESCRIPTION:Humans exhibit a strong tendency to associate with those similar to them. This tendency\, termed homophily in the social sciences\, impacts both the structure of society and its outcomes. In this talk\, Nicole Immorlica discusses the mathematics of homophily. She first quantifies its theoretical implications for geographic segregation. We will see that even tolerant societies exhibit segregation\, as weak local preferences can have ripple effects with global consequences. This geographic segregation\, in turn\, reinforces homophily. Immorlica then explores the role of homophily in inequality and economic productivity. She starts from the observation that most employment is driven by referrals. As social networks tend to exhibit homophily\, these referrals are also homophilous\, perpetuating existing inequality. This inequality\, in turn\, is harmful to productivity\, causing inefficiencies in the economy. She concludes by suggesting policy interventions that can both reduce inequality and improve productivity.  Finally\, should time permit\, she explores a rational basis for homophily in social networks\, showing that people prefer to listen to those similar to them because they get more accurate information from such interactions. URL:https://seasevents.nmsdev7.com/event/cis-seminar-birds-of-a-feather-flock-together-how-homophily-leads-to-segregation-inequality-and-inefficiency-and-what-we-can-do-about-it/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20230217T103000 DTEND;TZID=America/New_York:20230217T114500 DTSTAMP:20260405T015106 CREATED:20230124T154301Z LAST-MODIFIED:20230124T154301Z UID:10007442-1676629800-1676634300@seasevents.nmsdev7.com SUMMARY:Spring 2023 GRASP on Robotics: Jeremy D. Brown\, Johns Hopkins University\, "Understanding the Utility of Haptic Feedback in Telerobotic Devices" DESCRIPTION:This is a hybrid event with in-person attendance in Wu and Chen and virtual attendance via Zoom. This week’s presenter will be in-person as well.  \n  \nABSTRACT\nThe human body is capable of dexterous manipulation in many different environments. Some environments\, however\, are challenging to access because of distance\, scale\, and limitations of the body itself. In many of these situations\, access can be effectively restored via a telerobot. Dexterous manipulation through a telerobot is possible only if the telerobot can accurately relay any sensory feedback resulting from its interactions in the environment to the operator. In this talk\, I will discuss recent work from our lab focused on the application of haptic feedback in various telerobotic applications. I will begin by describing findings from recent investigations comparing different haptic feedback and autonomous control approaches for upper-extremity prosthetic limbs\, as well as the cognitive load of haptic feedback in these prosthetic devices. I will then discuss recent discoveries on the potential benefits of haptic feedback in robotic minimally invasive surgery (RAMIS) training. Finally\, I will discuss current efforts in our lab to measure haptic perception through novel telerobotic interfaces. URL:https://seasevents.nmsdev7.com/event/spring-2023-grasp-on-robotics-jeremy-d-brown/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="General Robotics%2C Automation%2C Sensing and Perception (GRASP) Lab":MAILTO:grasplab@seas.upenn.edu END:VEVENT END:VCALENDAR