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DTSTART;TZID=America/New_York:20220131T120000
DTEND;TZID=America/New_York:20220131T130000
DTSTAMP:20260406T091231
CREATED:20220131T130732Z
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SUMMARY:PSOC@Penn Seminar: "Unravelling the differences of copy number variations (CNV) and loss of heterozygosity (LOH) between solid and liquid tumors" (Mai Wang)
DESCRIPTION:Physical Sciences in Oncology Center PSOC@Penn \nSpring 2022 Hybrid-Seminar Series \nTowne 225 / Raisler Lounge @ Noon (EST) \nFor Zoom link \, please contact manu@seas.upenn.edu
URL:https://seasevents.nmsdev7.com/event/psocpenn-seminar-unravelling-the-differences-of-copy-number-variations-cnv-and-loss-of-heterozygosity-loh-between-solid-and-liquid-tumors-mai-wang/
LOCATION:Raisler Lounge (Room 225)\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar,Doctoral,Graduate,Student
ORGANIZER;CN="PSOC":MAILTO:manu@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220201T100000
DTEND;TZID=America/New_York:20220201T113000
DTSTAMP:20260406T091231
CREATED:20220118T211746Z
LAST-MODIFIED:20220118T211746Z
UID:10007023-1643709600-1643715000@seasevents.nmsdev7.com
SUMMARY:MEAM Seminar: "Mechanistic Insights into Crystalline Interfaces via Thermal Fluctuations"
DESCRIPTION:Interfaces such as grain boundaries are ubiquitous in crystalline materials and have provided a fertile area of research over decades. Their importance stems from the numerous critical phenomena associated with them\, such as grain boundary sliding\, migration\, and interaction with other defects that govern the mechanical properties of materials. Although these crystalline interfaces exhibit small out-of-plane fluctuations\, statistical thermodynamics of membranes has been effectively used to extract relevant physical quantities such as the interface free energy\, grain boundary stiffness\, and interfacial mobility. \nIn this talk\, I will put forward the viewpoint that monitoring thermal fluctuations of crystalline interfaces by way of molecular dynamics can serve as a computational microscope for gaining insights into the thermodynamic and kinetic properties of grain boundaries and present a rich source of future study. In particular\, the talk will present how we use thermal fluctuations to estimate the grain boundary stiffness and mobility of grain boundaries by modeling them as Brownian particles.
URL:https://seasevents.nmsdev7.com/event/meam-seminar-mechanistic-insights-into-crystalline-interfaces-via-thermal-fluctuations/
LOCATION:Zoom – Email MEAM for Link\, peterlit@seas.upenn.edu
CATEGORIES:Seminar
ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220201T153000
DTEND;TZID=America/New_York:20220201T163000
DTSTAMP:20260406T091231
CREATED:20220125T183901Z
LAST-MODIFIED:20220125T183901Z
UID:10007037-1643729400-1643733000@seasevents.nmsdev7.com
SUMMARY:CIS Seminar: "Trustworthy Machine Learning Systems via PAC Uncertainty Quantification"
DESCRIPTION:Machine learning models are increasingly being incorporated into real-world systems\, targeting domains such as robotics\, healthcare\, and software systems. A key challenge is ensuring that such systems are trustworthy. I will describe a novel strategy for composing machine learning models while providing provable correctness guarantees. First\, we show how to quantify the uncertainty of any given model in a way that satisfies PAC correctness guarantees. Second\, we show how to compose guarantees for individual models to obtain a guarantee for the overall system. Then\, I will discuss applications to ensuring safety in reinforcement learning from visual inputs\, and to speeding up inference time of deep neural networks. I will conclude with ongoing work on preserving correctness guarantees in the face of distribution shift.
URL:https://seasevents.nmsdev7.com/event/cis-seminar-trustworthy-machine-learning-systems-via-pac-uncertainty-quantification/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220202T150000
DTEND;TZID=America/New_York:20220202T160000
DTSTAMP:20260406T091231
CREATED:20220131T142848Z
LAST-MODIFIED:20220131T142848Z
UID:10007051-1643814000-1643817600@seasevents.nmsdev7.com
SUMMARY:Spring 2022 GRASP SFI: Anthony Bisulco\, University of Pennsylvania\, “A Tutorial on Neuromorphic Vision for High-Speed Perception”
DESCRIPTION:This seminar will be held in person in Levine 307 as well as via Zoom. \nMobile robot systems operate in dynamic environments\, such as forests\, caves\, or roadways\, where they must perceive and react to incoming stimuli. Each of these environments presents unique challenges such as perception in low-light conditions\, high-speed understanding of objects\, and low power requirements. Neuromorphic Vision Systems such as event-based cameras have appealing properties for the above challenges such as high-temporal resolution\, low-power footprint\, and high-dynamic-range. As opposed to conventional frame-based imagers\, event-based cameras output a stream of asynchronous events consisting of spatial illumination changes. This presents an expansive new processing model for event-based computer vision applications. In this talk\, I will begin with a tutorial on event-based cameras\, review processing techniques for the event-stream\, and highlight our recent work on developing high-speed perception action systems for object catching.
URL:https://seasevents.nmsdev7.com/event/spring-2022-grasp-sfi-anthony-bisulco-university-of-pennsylvania-a-tutorial-on-neuromorphic-vision-for-high-speed-perception/
LOCATION:Levine 307\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="General Robotics%2C Automation%2C Sensing and Perception (GRASP) Lab":MAILTO:grasplab@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220202T153000
DTEND;TZID=America/New_York:20220202T163000
DTSTAMP:20260406T091231
CREATED:20220111T233456Z
LAST-MODIFIED:20220111T233456Z
UID:10007007-1643815800-1643819400@seasevents.nmsdev7.com
SUMMARY:CBE Seminar: "From Trash to Treasure: Advancing the Heterogeneous Catalytic Deconstruction and Upcycling of Waste Polyolefins"
DESCRIPTION:Abstract \nThe rapid global consumption of single-use plastics has caused an unsustainable accumulation of plastic waste in landfills and the environment. Unfortunately\, current mechanical recycling methods are expensive and produce lower-quality products. New strategies in targeted chemical upcycling of waste plastics offer unique opportunities for selective depolymerization of polyolefins to higher value chemicals under milder conditions than thermal deconstruction or pyrolysis. Inspired by recent developments in the depolymerization of lignin\, we turned to the method of hydrogenolysis to break the strong C-C bonds in polyolefins. This talk will cover our efforts in identifying a class of ruthenium-based materials as active and selective heterogeneous catalysts for the depolymerization of polyolefin waste\, catalyst support modification strategies to further improve selectivity towards processible liquid alkanes\, and new frameworks for the chemical upcycling of waste plastics and complex mixed waste streams to enable a circular carbon economy.
URL:https://seasevents.nmsdev7.com/event/cbe-seminar-from-trash-to-treasure-advancing-the-heterogeneous-catalytic-deconstruction-and-upcycling-of-waste-polyolefins/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220203T103000
DTEND;TZID=America/New_York:20220203T113000
DTSTAMP:20260406T091231
CREATED:20220126T164120Z
LAST-MODIFIED:20220126T164120Z
UID:10007040-1643884200-1643887800@seasevents.nmsdev7.com
SUMMARY:MSE Seminar: "Thermodynamic contributions to glass fragility"
DESCRIPTION:Liquid fragility characterizes the rate of drop off in viscosity of a glass-forming liquid as its temperature increases above the glass transition. This property is fundamental to glass physics and of critical importance for engineering applications\, yet its origin is unclear. Competing theories suggest that vibrational properties may play a role in fragility by contributing entropy to the large excess entropy of the undercooled liquid over the crystal above the glass transition. In this talk\, we will demonstrate the use of in situ inelastic neutron scattering to probe the vibrational properties of a series of glasses with varying fragilities. We will demonstrate that event-based neutron scattering allows collection of the phonon density of states in as little as two minutes\, enabling capture of vibrational dynamics in the narrow stable window of the undercooled liquid. We will discuss the correlation between excess vibrational entropy in the undercooled liquid and liquid fragility. Finally\, we will discuss these new results in the context of a universal understanding of fragility and vibrational contributions to the thermodynamics of the glass transition.
URL:https://seasevents.nmsdev7.com/event/mse-seminar-thermodynamic-contributions-to-glass-fragility/
LOCATION:https://upenn.zoom.us/j/96715197752
ORGANIZER;CN="Materials Science and Engineering":MAILTO:johnruss@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220203T153000
DTEND;TZID=America/New_York:20220203T163000
DTSTAMP:20260406T091231
CREATED:20220122T162713Z
LAST-MODIFIED:20220122T162713Z
UID:10007033-1643902200-1643905800@seasevents.nmsdev7.com
SUMMARY:BE Seminar: "From Bench to Pet-Side: Intratumoral Immunotherapy Principles and Practice" (Noor Momin)
DESCRIPTION:Immunotherapies harness the body’s immune system to fight disease. Such therapies can help unleash an immune attack against diseased tissues but can inadvertently instigate an attack on healthy tissues. As a result\, many promising immunotherapies face major toxicities\, limiting their clinical use. By employing an iterative process that entails measuring\, making\, and modeling to manipulate immunity\, we can develop effective immunotherapies for any ailment – from cancer to cardiovascular disease. \nIn this seminar\, I will describe our effort to develop a novel intratumorally-injected treatment to fight cancer safely and effectively. Cytokines are promising cancer immunotherapies plagued by life-threatening toxicity. Injecting cytokines directly into tumors could provide a method of confining its benefits to the cancerous tissue and away from healthy tissues\, but previous attempts to do this have resulted in the cytokines rapidly leaking out of the tumor and ravaging healthy tissues. To this end\, we first engineered a strategy to retain cytokines injected in a tumor\, thereby safely exerting their anti-tumor activity. Then\, we generated a computational framework that outlines the pharmacokinetic underpinnings of an effective tumor localized immunotherapy. Lastly\, we commenced a clinical trial in companion (i.e.\, pet) dogs with naturally-occurring cancer aimed at generating guidelines for the administration of tumor localized cytokines in humans. Together\, this work powers safe and effective local immunotherapies for cancer treatment.
URL:https://seasevents.nmsdev7.com/event/be-seminar-from-bench-to-pet-side-intratumoral-immunotherapy-principles-and-practice-noor-momin/
LOCATION:216 Moore Building
ORGANIZER;CN="Bioengineering":MAILTO:be@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220203T153000
DTEND;TZID=America/New_York:20220203T163000
DTSTAMP:20260406T091231
CREATED:20220125T185819Z
LAST-MODIFIED:20220125T185819Z
UID:10007038-1643902200-1643905800@seasevents.nmsdev7.com
SUMMARY:CIS Seminar: "Sublinear Algorithms for Massive Datasets"
DESCRIPTION:The influx of massive data systems poses a unique challenge for algorithms research. In this modern era\, the classical theory of algorithms is often insufficient\, and our goal is to develop the theory of sublinear computation. \nThis talk will cover various scenarios where the resources used by an algorithm (running time\, memory\, number of measurements\, … etc) should be significantly smaller than the input size. We will spend most of the time on sublinear time algorithms for similarity search in high-dimensional spaces and sublinear space algorithms for the optimal transport problem\, where we will present new algorithmic and analytical techniques for tackling these questions. A central theme throughout the talk is the notion of randomized space partitions\, and how they lead to algorithms which are simple\, have provable guarantees\, and are extremely useful.
URL:https://seasevents.nmsdev7.com/event/cis-seminar-sublinear-algorithms-for-massive-datasets/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220203T153000
DTEND;TZID=America/New_York:20220203T163000
DTSTAMP:20260406T091231
CREATED:20220131T145143Z
LAST-MODIFIED:20220131T145143Z
UID:10007052-1643902200-1643905800@seasevents.nmsdev7.com
SUMMARY:BE Seminar: “Intratumoral Immunotherapy Principles and Practice” (Noor Momin)
DESCRIPTION:This seminar will be held live and broadcast on zoom – check email for zoom link or contact ksas@seas.upenn.edu. \nImmunotherapies harness the body’s immune system to fight disease. Such therapies can help unleash an immune attack against diseased tissues but can inadvertently instigate an attack on healthy tissues. As a result\, many promising immunotherapies face major toxicities\, limiting their clinical use. By employing an iterative process that entails measuring\, making\, and modeling to manipulate immunity\, we can develop effective immunotherapies for any ailment – from cancer to cardiovascular disease. \nIn this seminar\, I will describe our effort to develop a novel intratumorally-injected treatment to fight cancer safely and effectively. Cytokines are promising cancer immunotherapies plagued by life-threatening toxicity. Injecting cytokines directly into tumors could provide a method of confining its benefits to the cancerous tissue and away from healthy tissues\, but previous attempts to do this have resulted in the cytokines rapidly leaking out of the tumor and ravaging healthy tissues. To this end\, we first engineered a strategy to retain cytokines injected in a tumor\, thereby safely exerting their anti-tumor activity. Then\, we generated a computational framework that outlines the pharmacokinetic underpinnings of an effective tumor localized immunotherapy. Lastly\, we commenced a clinical trial in companion (i.e.\, pet) dogs with naturally-occurring cancer aimed at generating guidelines for the administration of tumor localized cytokines in humans. Together\, this work powers safe and effective local immunotherapies for cancer treatment.
URL:https://seasevents.nmsdev7.com/event/be-seminar-noor-momin/
LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar,Postdoctoral
ORGANIZER;CN="Bioengineering":MAILTO:be@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220204T103000
DTEND;TZID=America/New_York:20220204T114500
DTSTAMP:20260406T091231
CREATED:20220119T193922Z
LAST-MODIFIED:20220119T193922Z
UID:10007026-1643970600-1643975100@seasevents.nmsdev7.com
SUMMARY:GRASP on Robotics: Stefanos Nikolaidis\, University of Southern California\, “Towards Robust Human-Robot Interaction: A Quality Diversity Approach”
DESCRIPTION:The growth of scale and complexity of interactions between humans and robots highlights the need for new computational methods to automatically evaluate novel algorithms and applications. Exploring the diverse scenarios of interaction between humans and robots in simulation can improve understanding of complex human-robot interaction systems and avoid potentially costly failures in real-world settings. \nIn this talk\, I propose formulating the problem of automatic scenario generation in human-robot interaction as a quality diversity problem\, where the goal is not to find a single global optimum\, but a diverse range of failure scenarios that explore both environments and human actions. I show how standard quality diversity algorithms can discover surprising and unexpected failure cases in the shared autonomy domain. I then discuss the development of a new class of quality diversity algorithms that significantly improve the search of the scenario space and the integration of these algorithms with generative models\, which enables the generation of complex and realistic scenarios. Finally\, I discuss applications in procedural content generation and human preference learning.
URL:https://seasevents.nmsdev7.com/event/grasp-on-robotics-towards-robust-human-robot-interaction-a-quality-diversity-approach/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
ORGANIZER;CN="General Robotics%2C Automation%2C Sensing and Perception (GRASP) Lab":MAILTO:grasplab@seas.upenn.edu
END:VEVENT
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