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DTSTART;TZID=America/New_York:20211101T100000
DTEND;TZID=America/New_York:20211101T120000
DTSTAMP:20260406T105654
CREATED:20211027T183829Z
LAST-MODIFIED:20211027T183829Z
UID:10006946-1635760800-1635768000@seasevents.nmsdev7.com
SUMMARY:CBE PhD Dissertation Defense | “3D-stiffness Microenvironment Leads to Nuclear Envelope Rupture\, DNA Damage\, and Genome Variation”
DESCRIPTION:Abstract: \n“Solid tumor cells grow in a stiff microenvironment with dense extracellular matrix (ECM) and condensed packing of adjacent cells. Tumor cells are capable of migrating through constricted pores formed by ECM or surrounded by other cells\, and the nuclear envelope can break with repair factor mislocalization\, further leading to DNA damage and genetic changes\, or even accumulated to be genomic variations. Cell division\, likewise\, is confined by a stiff niche of adjacent cells and extracellular matrix\, and such confinement has been reported to cause chromosome mis-segregation. The chromosome-loss live cell reporter system was developed to prove that cells undergoing specific types of chromosome missegregation can survive and maintain heritability\, resulting in permanent genomic variations. Mitotic cells under in vitro confinement and in vivo conditions exhibit more abnormal division and more fluorescence-null reporter-negative cells\, for both cancer and normal types. Confinement and SAC inhibition both lead to chromosome mis-segregation but do not superimpose\, and Topoisomerase IIa plays an essential role in cells to survive after confined mitosis. Myosin II was found to lead to increased nuclear envelope rupture and\, therefore\, more DNA damage\, while it protects mitotic cell rounding within 3D confined environments\, since the increase of reporter-negative cells was observed after Myosin II knockdown. “
URL:https://seasevents.nmsdev7.com/event/cbe-phd-dissertation-defense-3d-stiffness-microenvironment-leads-to-nuclear-envelope-rupture-dna-damage-and-genome-variation/
LOCATION:Levine 307\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Doctoral,Graduate,Student,Dissertation or Thesis Defense
ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211101T120000
DTEND;TZID=America/New_York:20211101T130000
DTSTAMP:20260406T105654
CREATED:20210913T140523Z
LAST-MODIFIED:20210913T140523Z
UID:10006890-1635768000-1635771600@seasevents.nmsdev7.com
SUMMARY:PSOC@Penn Seminar: Cindy Reinhart King
DESCRIPTION:Room: Towne 225/Raisler Lounge \nFor zoom link\, contact manu@seas.upenn.edu.
URL:https://seasevents.nmsdev7.com/event/psocpenn-seminar-cindy-reinhart-king/
LOCATION:Raisler Lounge (Room 225)\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="PSOC":MAILTO:manu@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211102T100000
DTEND;TZID=America/New_York:20211102T113000
DTSTAMP:20260406T105654
CREATED:20211011T185515Z
LAST-MODIFIED:20211011T185515Z
UID:10006926-1635847200-1635852600@seasevents.nmsdev7.com
SUMMARY:MEAM Seminar: "Designing Robotic Systems with Collective Embodied Intelligence"
DESCRIPTION:Natural swarms exhibit sophisticated colony-level behaviors with remarkable scalability and error tolerance. Their evolutionary success stems from more than just intelligent individuals\, it hinges on their morphology\, their physical interactions\, and the way they shape and leverage their environment. Mound-building termites\, for instance\, are believed to use their own body as a template for construction; the resulting dirt mound serves\, among other things\, to regulate volatile pheromone cues which in turn guide further construction and colony growth. Throughout this talk I will argue how we can leverage the same principles to achieve greater performance in robot collectives\, by paying attention to the interplay between control and hardware\, as well as direct- and environmentally-mediated coordination between robots. I will exemplify the strength and challenges of this approach through cell-inspired\, soft\, single- and multi-robot systems for exploration; micro-scale robots for bio-medical applications; termite-inspired multi-robot systems for construction- and excavation; and bio-hybrid systems for agricultural monitoring.
URL:https://seasevents.nmsdev7.com/event/meam-seminar-designing-robotic-systems-with-collective-embodied-intelligence/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211102T110000
DTEND;TZID=America/New_York:20211102T120000
DTSTAMP:20260406T105654
CREATED:20211027T131240Z
LAST-MODIFIED:20211027T131240Z
UID:10006945-1635850800-1635854400@seasevents.nmsdev7.com
SUMMARY:ESE Grace Hopper Lecture  - "A Communications Perspective on Digital Privacy"
DESCRIPTION:Many of the activities in cyberspace\, from social networking to the use of mobile apps\, leave digital footprints compromising the users’ privacy.  As digital tracking technologies become more sophisticated and pervasive\, there is a need to understand and quantify the users’ privacy risk\, that is\, what is the likelihood that users in cyberspace can be uniquely identified from their activities? \nIn this talk\, we focus on de-anonymization attacks\, where publicly and privately available information about users\, represented as connectivity graphs\, are leveraged to compromise user identities. We model the de-anonymization attack as a graph matching  problem in which  we have two correlated stochastic graphs the first of which has labeled vertices\, whereas the second one is unlabeled. The goal is to recover the labels of the second graph by using the correlation structure. We explore how graph matching can be posed as a communications problem\, and tools from information theory\, communication theory and probability can be used to derive theoretical guarantees and algorithms for graph matching\, thereby providing a framework for quantifying the privacy risk of users in the cyberspace.
URL:https://seasevents.nmsdev7.com/event/ese-grace-hopper-lecture-a-communications-perspective-on-digital-privacy/
LOCATION:Raisler Lounge (Room 225)\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211102T153000
DTEND;TZID=America/New_York:20211102T163000
DTSTAMP:20260406T105654
CREATED:20211018T160647Z
LAST-MODIFIED:20211018T160647Z
UID:10006933-1635867000-1635870600@seasevents.nmsdev7.com
SUMMARY:CIS Seminar: "Sketching Algorithms"
DESCRIPTION:Abstract:\nA “sketch” is a data structure supporting some pre-specified set of queries and updates to a database while consuming space substantially (often exponentially) less than the information theoretic minimum required to store everything seen\, and thus can also be seen as some form of functional compression. A “streaming algorithm” is simply a data structure that maintains a sketch dynamically as data is updated. The advantages of sketching include less memory consumption\, faster algorithms\, and reduced bandwidth requirements in distributed computing environments. Despite decades of work in the area\, some of the most basic questions still remain open or were only resolved recently. In this talk\, I survey recent results across a variety of sketching topics.
URL:https://seasevents.nmsdev7.com/event/cis-seminar-sketching-algorithms/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar,Colloquium
ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211102T190000
DTEND;TZID=America/New_York:20211102T200000
DTSTAMP:20260406T105654
CREATED:20210929T145452Z
LAST-MODIFIED:20210929T145452Z
UID:10006919-1635879600-1635883200@seasevents.nmsdev7.com
SUMMARY:ODEI Spotlight: Trauma Informed Care and LGBT Health
DESCRIPTION:Stephanie Tillman\, CNM — the Feminist Midwife — will discuss LGBT health through the lens of trauma informed care. Registration required\, more info TBA. Find full details on the event page here.
URL:https://seasevents.nmsdev7.com/event/odei-spotlight-trauma-informed-care-and-lgbt-health/
LOCATION:LGBT Center – 3907 Spruce Street\, 3907 Spruce Street\, Philadelphia\, United States
CATEGORIES:Diversity, Equity and Inclusion
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211103T150000
DTEND;TZID=America/New_York:20211103T160000
DTSTAMP:20260406T105654
CREATED:20211029T172434Z
LAST-MODIFIED:20211029T172434Z
UID:10006947-1635951600-1635955200@seasevents.nmsdev7.com
SUMMARY:Fall 2021 GRASP SFI: "Studying Bias and Representation in Sociotechnical Systems"
DESCRIPTION:*This will be a HYBRID Event with in-person attendance in Levine 307 and Virtual attendance via Zoom here… \nAlgorithms play a central role in our lives today\, mediating our access to civic engagement\, social connections\, employment opportunities\, news media and more. While the sociotechnical systems deploying these algorithms—search engines\, social networking sites\, and others—have the potential to dramatically improve human life\, they also run the risk of reproducing or intensifying social inequities and tensions. In my research\, I ask whether and how these systems are biased and how those biases impact users\, towards the aim of building better ones. In this talk\, I will describe my work conducting algorithm audits and randomized controlled user experiments to study representation and bias\, touching on examples including my recent audits of gender and racial representation in image search results and partisan political media in web search. I will conclude by discussing my most recent work building tools to extend such audits into new domains and make them more accessible and sustainable for researchers.
URL:https://seasevents.nmsdev7.com/event/fall-2021-grasp-sfi-studying-bias-and-representation-in-sociotechnical-systems/
LOCATION:PA
ORGANIZER;CN="General Robotics%2C Automation%2C Sensing and Perception (GRASP) Lab":MAILTO:grasplab@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211103T170000
DTEND;TZID=America/New_York:20211103T180000
DTSTAMP:20260406T105654
CREATED:20211026T181426Z
LAST-MODIFIED:20211026T181426Z
UID:10006944-1635958800-1635962400@seasevents.nmsdev7.com
SUMMARY:Homecoming 2021: Penn Engineering Update and "Engineering living biology with nanomachines"
DESCRIPTION:This special event is part of the virtual programming for Penn Homecoming 2021 and is open to all alumni\, parents\, and friends. Nemirovsky Family Dean and Professor Vijay Kumar will give a State of the School Update including an overview of the newly established Center for Precision Engineering for Health\, which will bring together researchers spanning multiple scientific fields to develop novel therapeutic biomaterials. \nDean Kumar’s update will be followed by a presentation\, “Engineering living biology with nanomachines\,” by Jennifer E. Phillips-Cremins\, Associate Professor and Dean’s Faculty Fellow in Bioengineering and Genetics\, and Marc Miskin\, Assistant Professor in Electrical and Systems Engineering\, with a moderated Q&A session. \nRegister here. After registration\, attendees will receive a link to view the live discussion the day prior to the event.
URL:https://seasevents.nmsdev7.com/event/penn-engineering-update/
LOCATION:PA
ORGANIZER;CN="Development and Alumni Relations":MAILTO:alumni@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211104T123000
DTEND;TZID=America/New_York:20211104T133000
DTSTAMP:20260406T105654
CREATED:20211021T182847Z
LAST-MODIFIED:20211021T182847Z
UID:10006936-1636029000-1636032600@seasevents.nmsdev7.com
SUMMARY:MSE Seminar: "Lansdcapes of Glass"
DESCRIPTION:If cooled sufficiently quickly\, the disorder of a liquid can be “quenched” or locked in place; the resulting amorphous solid is glass. Although it appears to be solid on human timescales\, glass continues to creep due to thermal vibrations at the molecular scale. Consider now a pile of sand; it too is a disordered system\, but the grains are too massive for such thermal effects to be relevant. Yet\, soils in nature relentlessly creep\, on hillslopes below the angle of repose. The unchallenged dogma is that this creep is driven by churning of soil by (bio)physical disturbances. River-bed sediments also creep\, at flows below the threshold of motion\, though this has received far less attention. In this talk Dr. Jerolmack focuses on recent work from his group and others that examines the origins of granular creep in hillslope and river systems\, and the consequences of these findings for understanding actual landscapes. Our observations\, arising from first-of-their-kind experiments and simulations\, reveal surprises for both materials and geology. First\, gravity-driven granular creep occurs with minimal disturbance\, with rates and styles comparable to field observations. Second\, this creep shares deep similarities with the behavior of glass\, suggesting that mechanical disturbance in granular systems plays a role akin to thermal fluctuations in molecular systems. Third\, fluid-driven creep in rivers has similar behavior to gravity-driven soil creep on hillsides. In both cases this creep acts to “harden” the bed\, by compaction and the creation of structures that resist motion. Thus\, sediment beds maintain a memory of their history of forcing\, that dicates the threshold for landsliding (hillslopes) or entrainment (rivers). The upshot is that Earth’s landscapes appear to be glassy\, and that viewing the Earth’s surface as a soft-matter landscape yields (pun intended) new insights with practical consequences.
URL:https://seasevents.nmsdev7.com/event/mse-seminar-lansdcapes-of-glass/
LOCATION:Auditorium\, LRSM Building\, 3231 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Colloquium
ORGANIZER;CN="Materials Science and Engineering":MAILTO:johnruss@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211104T173000
DTEND;TZID=America/New_York:20211104T190000
DTSTAMP:20260406T105654
CREATED:20211026T154612Z
LAST-MODIFIED:20211026T154612Z
UID:10006943-1636047000-1636052400@seasevents.nmsdev7.com
SUMMARY:ODEI Spotlight: Critical Race Theory and DEI: From Theory to Practice
DESCRIPTION:The African-American Resource Center & Office of Affirmative Action Presents:\n \nCritical Race Theory and DEI: From Theory to Practice \nJoin us as we examine the language switch from Critical Race Theory to Diversity Equity and Inclusion\, \nand what each term means and what DEI means and looks like at Penn. \n  \nZoom Link:  \nhttp://upenn.zoom.us/j/7443577924 \n  \nPanelists: \nBeverly A. Crawford\, Director of Diversity and Inclusion\, Department of Preventive and Restorative Sciences \nCaptain W. Nicole McCoy\, Commanding Officer of Diversity\, Equity\, and Inclusion\, Public Safety \nMonica Monroe\, Associate Dean for Equity & Inclusion\, Carey Law School \n  \nModerator: \nValerie Dorsey Allen\, Director\, African-American Resource Center \n  \nKeynote Speaker: \nChaz L. Howard\, Penn’s Vice President for Social Equity and Community
URL:https://seasevents.nmsdev7.com/event/odei-spotlight-critical-race-theory-and-dei-from-theory-to-practice/
LOCATION:https://upenn.zoom.us/j/96715197752
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211105T103000
DTEND;TZID=America/New_York:20211105T114500
DTSTAMP:20260406T105654
CREATED:20211029T173157Z
LAST-MODIFIED:20211029T173157Z
UID:10006948-1636108200-1636112700@seasevents.nmsdev7.com
SUMMARY:GRASP on Robotics: "Event-based Neuromorphic Perception and Computation: The Future of Sensing and AI"
DESCRIPTION:*This will be a HYBRID Event with in-person attendance in Wu & Chen Auditorium and Virtual attendance via Zoom Webinar here. \nThere has been significant research over the past two decades in developing new systems for spiking neural computation. The impact of neuromorphic concepts on recent developments in optical sensing\, display and artificial vision is presented. State-of-the-art image sensors suffer from severe limitations imposed by their very principle of operation. These sensors acquire the visual information as a series of ’snapshots’ recorded at discrete point in time\, hence time-quantized at a predetermined frame rate\, resulting in limited temporal resolution\, low dynamic range and a high degree of redundancy in the acquired data. Nature suggests a different approach: Biological vision systems are driven and controlled by events happening within the scene in view\, and not — like image sensors — by artificially created timing and control signals that have no relation whatsoever to the source of the visual information. Translating the frameless paradigm of biological vision to artificial imaging systems implies that control over the acquisition of visual information is no longer being imposed externally to an array of pixels but the decision making is transferred to the single pixel that handles its own information individually. It is demonstrated that bio-inspired vision systems have the potential to outperform conventional\, frame-based vision acquisition and processing systems in many application fields and to establish new benchmarks in terms of redundancy suppression/data compression\, dynamic range\, temporal resolution and power efficiency to realize advanced functionality like 3D vision\, object tracking\, motor control\, visual feedback loops and even allow us to rethink our current paradigm of computation. The ultimate goal is to develop brain-inspired general purpose computation architectures that can breach the current bottleneck introduced by the von Neumann architecture.
URL:https://seasevents.nmsdev7.com/event/grasp-on-robotics-event-based-neuromorphic-perception-and-computation-the-future-of-sensing-and-ai/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="General Robotics%2C Automation%2C Sensing and Perception (GRASP) Lab":MAILTO:grasplab@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211105T140000
DTEND;TZID=America/New_York:20211105T150000
DTSTAMP:20260406T105654
CREATED:20210816T131455Z
LAST-MODIFIED:20210816T131455Z
UID:10006853-1636120800-1636124400@seasevents.nmsdev7.com
SUMMARY:PICS Colloquium: "From atoms to emergent mechanisms with information bottleneck and diffusion probabilistic models"
DESCRIPTION:Abstract: The ability to rapidly learn from high-dimensional data to make reliable predictions about the future is crucial in many contexts. This could be a fly avoiding predators\, or the retina processing terabytes of data guiding complex human actions. Modern day artificial intelligence (AI) aims to mimic this fidelity and has been successful in many domains of life. It is tempting to ask if AI could also be used to understand and predict the emergent mechanisms across timescales for complex molecules with millions of atoms. In this talk I will show that certain flavors of AI can indeed help us understand generic molecular structure and dynamics\, and also predict it even in situations with arbitrary long memories. However this requires close integration of AI with old and new ideas in statistical mechanics. I will talk about such methods developed by my group (1-3) using information bottleneck\, denoising probabilistic models and long short-term memory networks\, focusing on the first one or two frameworks in interest of time. I will demonstrate the methods on different problems\, where we predict mechanisms at timescales much longer than milliseconds while keeping all-atom/femtosecond resolution. These include ligand dissociation from flexible protein/RNA and crystal nucleation with competing polymorphs. \nReferences:  \n1. Wang\, Y.\, Ribeiro\, J.M.L. & Tiwary\, P. Past–future information bottleneck for sampling molecular reaction coordinate simultaneously with thermodynamics and kinetics. Nat. Commun. 10\, 3573 (2019).  \n2. Wang\, Y.\, & Tiwary\, P. Denoising diffusion probabilistic models for replica exchange. arXiv preprint arXiv:2107.07369 (2021). \n3. Tsai\, S.T\, Kuo\, E.J. & Tiwary\, P.  Learning Molecular Dynamics with Simple Language Model built upon Long Short-Term Memory Neural Network. Nat. Commun. 11\, 5115 (2020).
URL:https://seasevents.nmsdev7.com/event/pics-colloquium-from-atoms-to-emergent-mechanisms-with-information-bottleneck-and-diffusion-probabilistic-models/
LOCATION:Zoom – email kathom@seas.upenn.edu
CATEGORIES:Colloquium
ORGANIZER;CN="Penn Institute for Computational Science (PICS)":MAILTO:dkparks@seas.upenn.edu
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