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    • BE Doctoral Dissertation Defense: “Pooled tagging of endogenous proteins for exploration of the human proteome driven by prime editing”

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    Colket Translational Research Building (Room 4040)

    The Department of Bioengineering at the University of Pennsylvania and Dr. Ophir Shalem are pleased to announce the Doctoral Dissertation Defense of Henry Sanchez.   Title: Pooled tagging of endogenous proteins for exploration of the human proteome driven by prime editing Date: September 21, 2023 Time: 3:00pm Location: Colket Translational Research Building (Room 4040) The public is welcome to attend.

    BE Seminar: “Engineering the cell-matrix interface – understanding and guiding cell function” (Claudia Loebel, University of Michigan)

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    216 Moore Building

    The native extracellular microenvironment dynamically remodels as cells synthesize, assemble, and remodel their surroundings during tissue development, injury, and repair. In my research group, we use engineered systems to both probe mechanisms of cell-extracellular matrix (ECM) interactions (e.g., mechanobiology) and to guide cell function towards therapeutic behaviors (e.g., tissue repair/regeneration). In this seminar, I will […]

    ESE Fall Seminar – “Tools for designing some exciting chips”

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    Berger Auditorium (Room 13), Skirkanich Hall 210 South 33rd Street, Philadelphia, PA, United States

    There is an enormous interest in developing customized, domain-specific systems-on-a-chip.  Continued improvement in computing efficiency requires functional specialization of hardware designs. But designing complex chips is difficult.   This talk presents the Chipyard framework, an integrated SoC design, simulation, and implementation environment for specialized compute systems. Chipyard includes configurable, composable, open-source, generator-based IP blocks that can […]

    CBE Seminar: “Design of Solid-state Nanomaterials for Electrocatalysis: A Case Study of Oxygen Evolution Reaction Electrocatalysts” (Yang, UIUC)

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    High-level control of atomic and surface structures is a hallmark of the application of nanomaterials in a range of electrochemical and electrocatalytic devices, such as water electrolyzer. They play critical roles in our effort to develop energy conversion and storage technologies that have net zero carbon impacts. Nanostructured metal oxides made for catalyzing the oxygen […]

    LSRM Presents The Robert Maddin Lecture in Materials Science: “Active & Adaptive Matter Driving Cell Dynamics”

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    Glandt Forum, Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA, United States

    Control of shape and movement is essential for cell physiology, from cell migration to control of tissue shape. The mechanical behaviors of living cells are controlled by materials constructed by protein-based assemblies within the cell interior.  These soft materials both regulate how forces generated by individual mechanoenzymes are transmitted to cell and tissue scales as […]

    MEAM Seminar: “Defending the Planet: The DART Mission, and Mechanics Among the Asteroids”

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    An on-orbit demonstration of asteroid deflection is a key test of our ability to defend the planet from an incoming asteroid. The recent DART (Double Asteroid Redirection Test) mission was NASA's demonstration of kinetic impactor technology, impacting an asteroid to adjust its speed and path. The DART spacecraft impacted the asteroid Dimorphos on September 26, […]

    ESE Fall Seminar – “Large Observational Study of the Causal Effects of a Nudge and the Geometry of Causality”

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    Glandt Forum, Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA, United States

    Nudges are interventions promoting healthy behavior without forbidding options or significant incentives. As an example of a nudge, the Apple Watch encourages users to stand by delivering a notification if they have been sitting for the first 50 minutes of an hour. Based on 76 billion minutes of observational standing data from 160,000 subjects in […]

    ESE PhD Thesis Defense: “Control of Multi-Contact Systems via Local Hybrid Models”

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    Room 35, Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA, United States

    For many important tasks such as manipulation and locomotion, robots need to make and break contact with their environment. Although such multi-contact systems are common, they pose a significant challenge when it comes to analysis and control. This thesis exploits the local hybrid structure of such problems and presents scalable and fast algorithmic solutions. First, […]

    Fall 2023 GRASP Seminar: Paul Debevec, Eyeline Studios Powered by Netflix, “From Virtual Cinematographhy to Virtual Production”

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    Levine 307 3330 Walnut Street, Philadelphia, PA, United States

    *This seminar will be held in-person in Levine 307 as well as virtually via Zoom. The seminar will NOT be recorded. ABSTRACT This talk will describe how virtual cinematography techniques developed at UC Berkeley for image-based modeling, rendering, and lighting helped enable iconic visual effects sequences in movies such as The Matrix, X-Men, Spider-Man 2, Benjamin […]

    ASSET Seminar: “Safety through Agility – Safe and Performant Control for Learning-Enabled Autonomous Systems” (Mangharam, Penn)

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    Levine 307 3330 Walnut Street, Philadelphia, PA, United States

    ABSTRACT: We present three approaches to combine formal methods, control theory, and machine learning for safe and performant autonomous systems.  Safe control for learning-enabled systems: We present our recent progress on how to learn safe adaptive behavior for highly interactive multi-agent systems. We will introduce how to quantify the uncertainty of closed-loop control systems using […]

    Fall 2023 GRASP SFI: Robert Baines, ETH Zürich, “Material system design for predictable shape-morphing robots”

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    Levine 307 3330 Walnut Street, Philadelphia, PA, United States

    This is a hybrid event with in-person attendance in Levine 307 and virtual attendance on Zoom. This week's speaker will be virtual.  ABSTRACT Robots are traditionally designed with immutable physical hardware and control policies that make them specialized for repetitive, structured tasks and environments. This talk presents work toward robots that actively change shape to […]