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    • CBE Seminar: “Energetic Constraints on Biological Assembly and Motion” (Murrell, Yale)

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    On small length-scales, the mechanics of soft materials may be dominated by their interfacial properties as opposed to their bulk properties. These effects are described by equilibrium models of elasto-capillarity and wetting. In these models, interfacial energies and bulk material properties are held constant. However, in biological materials, including living cells and tissues, these properties […]

    MSE Seminar: “Bioinspired Polymers for Tissue Repair and Regeneration” (Phillip B. Messersmith University of California – Berkeley)

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    It is of great interest for materials scientists to study wet biological adhesives as inspiration for synthetic adhesives that can perform well in wet conditions. A compelling example is given by the adhesive proteins secreted by marine mussels, which have inspired the development of synthetic polymer adhesives and coatings for adhesion to wet surfaces. Mussel […]

    ESE PhD Thesis Defense: “CyberCardia: Patient-specific Electrophysiological heart model for assisting left atrium arrhythmia ablation”

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    Room 313, Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA, United States

    Atrial arrhythmia is a prevalent heart disease that results in weak and irregular contractions of the atria. It affects millions of people worldwide. Cardiac ablation is among the most successful treatment options. During the procedure, catheters are inserted into the left atrium to map the atrium geometry and record endocardium electrograms that are then converted […]

    BE Seminar: “Robust CRISPR/Cas-based epigenome editing technologies for precision human cell engineering and mechanistic dissection of pathological gene expression” (Isaac Hilton, Rice University)

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    216 Moore Building

    Recent advances in CRISPR/Cas-based epigenome editing technologies have enabled programmable control over human gene expression, chromatin states, and genomic organization. Consequently, these emerging technologies have created new opportunities to engineer human cells for therapeutic benefit and catalyzed innovative ways to functionally interrogate gene regulatory mechanisms in situ. Toward these ends, we have recently developed new […]

    PRECISE Seminar: “Co-Optimizing Imaging, Computer Systems, and Biological Perception for Next-Generation Visual Computing Platforms”

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    Levine 307 3330 Walnut Street, Philadelphia, PA, United States

    Abstract Emerging platforms such as Augmented Reality (AR), Virtual Reality (VR), and autonomous machines, while are of a computing nature, intimately interact with both the environment and humans. They must be built, from the ground up, with principled considerations of three main components: imaging, computer systems, and human perception. This talk will make a case […]

    Fall 2023 GRASP on Robotics: Leslie Kaelbling, Massachusetts Institute of Technology, “Doing for our robots what nature did for us”

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    This is a hybrid event with in-person attendance in Wu and Chen and virtual attendance on Zoom. ABSTRACT We, as robot engineers, have to think hard about our role in the design of robots and how it interacts with learning, both in "the factory" (that is, at engineering time) and in "the wild" (that is, […]

    BE Doctoral Dissertation Defense: “Uncovering Structure-function Relationships in Chromatin Architecture” (Daniel Emerson)

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    BRB 253

    The Department of Bioengineering at the University of Pennsylvania and Dr. Jennifer Phillips-Cremins are pleased to announce the Doctoral Dissertation Defense of Daniel Emerson.   Title: Uncovering Structure-function Relationships in Chromatin Architecture   Date: October 20, 2023 Time: 1:00 PM Location: BRB 0253 Zoom link The Public is welcome to attend.

    MEAM Seminar: “Granular and Photoelastic Avalanches”

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    Flowing granular materials arise everywhere around us, in industry from pharmaceutical processes to bulk good transport lines, and in nature from snow avalanches to captivating dune fields. In landslides, we have an interesting interplay between microscale (grain-grain contacts) and macroscale processes (continuum behavior). In order to understand critical macroscale processes such as stability of a […]

    ESE Fall Seminar – “Acceleration by Stepsize Hedging”

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    Glandt Forum, Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA, United States

    Can we accelerate convergence of gradient descent without changing the algorithm --- just by optimizing stepsizes? Surprisingly, we show that the answer is yes. Our proposed Silver Stepsize Schedule optimizes strongly convex functions in $k^{\log_p 2} = k^{0.7864}$ iterations, where $p=1+\sqrt{2}$ is the silver ratio and $k$ is the condition number. This is intermediate between […]

    ASSET Seminar: “Towards a Design Flow for Verified AI-Based Autonomy” (Sajit A. Seshia, University of California, Berkeley)

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    Levine 307 3330 Walnut Street, Philadelphia, PA, United States

    ABSTRACT: Verified artificial intelligence (AI) is the goal of designing AI-based systems that have strong, ideally provable, assurances of correctness with respect to formally specified requirements. This talk will review the main challenges to achieving Verified AI, and the initial progress the research community has made towards this goal. A particular focus will be on […]

    Fall 2023 GRASP SFI: Matthew D. Kvalheim, University of Maryland, Baltimore County, “Discovering engineering (im)possibilities with geometry and topology”

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    Levine 307 3330 Walnut Street, Philadelphia, PA, United States

    This is a hybrid event with in-person attendance in Levine 307 and virtual attendance on Zoom. ABSTRACT I will describe engineering (im)possibilities discovered with geometry or topology. These provide or revoke “hunting licenses” for the search of quantities of interest in three contexts: feedback control, applied Koopmanism, and deep neural network autoencoders. Control-Lyapunov or barrier […]

    CBE Seminar: “Transformer-based Hybrid Modeling and Control of Evolving, Nonlinear Processes” (Kwon, Texas A&M University)

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    Traditionally, the dynamic modeling of chemical processes has relied on first-principles models grounded in fundamental physics and chemistry laws. These models, primarily formulated through differential equations with constant parameters, enable the calculation of control actions optimizing process operations, taking both process and actuator limitations into account. However, the ever-evolving and nonlinear nature of chemical processes […]