BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Penn Engineering Events - ECPv6.15.19//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-WR-CALNAME:Penn Engineering Events X-ORIGINAL-URL:https://seasevents.nmsdev7.com X-WR-CALDESC:Events for Penn Engineering Events REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:America/New_York BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20190310T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20191103T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20200308T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20201101T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20210314T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20211107T060000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=America/New_York:20200218T110000 DTEND;TZID=America/New_York:20200218T120000 DTSTAMP:20260408T055616 CREATED:20200207T164134Z LAST-MODIFIED:20200207T164134Z UID:10006403-1582023600-1582027200@seasevents.nmsdev7.com SUMMARY:ESE Seminar: "Nanophotonics: A High Bandwidth Optical Neural Interface" DESCRIPTION:Abstract\nLight is a powerful tool for interrogating and manipulating biological systems\, enabling targeted\nstimulation\, sensing\, and imaging. Optical methods such as optogenetics have transformed the study of\nneural circuits by making it possible to control neural activity using light. However\, there remains a critical\ndemand in research and medicine for miniaturized high resolution optical tools that can be embedded\ndeep within biological systems like the brain. The brain poses particular challenges due to the sheer\nnumber of densely packed interconnected neurons and the strong tissue scattering and absorption of\nlight. Nanophotonics\, or chip-scale optical circuits\, can enable unprecedented spatiotemporal resolution\nby leveraging nanoscale coherent control of a large set of optical channels within subwavelength\nwaveguides with high speed reconfiguration capability\, potential for integration with electronics\, and low-\ncost scalable manufacturability. This potential high bandwidth optical neural interface can be as thin as a\nfew neurons and have the ability to test spatial\, temporal\, and cell-type-specific aspects of neural\nencoding from cellular to system level within the brain. \nI will present the first implantable nanophotonic probe for optogenetic stimulation and recording of\nneurons in live mice. To achieve this\, we developed a reconfigurable visible nanophotonic platform based\non phase-controlled silicon nitride interferometric waveguide structures that can control cellular-sized\ncoherent emitters at blue wavelengths (peak of optogenetic actuators)\, far from traditional infrared\nwavelengths. This enabled a neural interface that can generate and read multi-neuron spike patterns\ndeep within the brain with single-cell and sub-millisecond resolution\, the highest resolution\nneuromodulation shown with an implantable probe. \nIn addition\, I will highlight two building blocks for future nanophotonic stimulation and sensing\ndevices that I developed using this platform: wide-angle chip-scale visible beam steering and multiplexing\nwithin a single waveguide by utilizing the transverse spatial degree-of-freedom of light. I will show how\nprecise phase control and novel nanoscale photonic design of these building blocks has been applied to\nemerging high bandwidth optical applications like portable display technology and quantum optical\nsystems. Finally\, I will present a future outlook towards a new generation of implantable and wearable\nbiomedical devices based on nanophotonic 3D light projection and sensing techniques including high-\ndimensional multiplexing\, volumetric beam shaping\, and quantum sensing. URL:https://seasevents.nmsdev7.com/event/ese-seminar-nanophotonics-a-high-bandwidth-optical-neural-interface/ LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Colloquium ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200218T103000 DTEND;TZID=America/New_York:20200218T120000 DTSTAMP:20260408T055616 CREATED:20200108T214119Z LAST-MODIFIED:20200108T214119Z UID:10006363-1582021800-1582027200@seasevents.nmsdev7.com SUMMARY:MEAM Seminar: "Cell Polarization and Growth" DESCRIPTION:Polarization is an essential behavior of living cells\, yet the dynamics of this symmetry-breaking process are not fully understood. We have developed a spatial stochastic model of cellular polarization during mating of Saccharomyces cerevisiae. Specifically we investigated the ability of yeast cells to sense a spatial gradient of mating pheromone and respond by forming a projection in the direction of the mating partner. Our results demonstrate that a spatial stochastic model of polarisome formation can more robustly reproduce two fundamental characteristics observed in wild-type cells: a tightly polarized phenotype and the ability to track moving pheromone input\, in comparison with the corresponding deterministic model. \nExisting models of cell polarization have focused solely on the biochemical signaling system. However\, there exists a well-known interplay between the growth of the mating projection and the mechanical forces of the cell wall in determining the shape of the cell. The cell wall of S. cerevisiae both defines its shape and provides the mechanical integrity necessary to sustain the large internal turgor pressure. Under the isotropic push of turgor pressure\, polarized expansion occurs via localized assembly of new cell wall material in combination with a simultaneous softening of the cell wall\, inducing it to yield and locally expand. Intracellular signaling directs enzymes with the ability to modify cross-linking of polymers in the cell wall to the region of polarization. The resulting mechanical feedback from the wall expansion initiates the delivery of raw material via vesicular transport. \nTo accurately model this complex biological phenomena\, we have developed a multiscale computational framework for simulating the coupling of the stochastic dynamics of biochemical reactions involved in shaping walled cells to the mechanical processes of cell wall expansion and growth. Our computational method exploits the time-scale separation between the relatively slow dynamics of the cell wall and the rapid interactions of the intercellular signaling network. URL:https://seasevents.nmsdev7.com/event/meam-seminar-cell-polarization-and-growth/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200213T150000 DTEND;TZID=America/New_York:20200213T160000 DTSTAMP:20260408T055616 CREATED:20200211T212333Z LAST-MODIFIED:20200211T212333Z UID:10006406-1581606000-1581609600@seasevents.nmsdev7.com SUMMARY:CIS Seminar: “User Generated Content: Opportunities to Inform Healthcare” DESCRIPTION:Abstract \nWhen individuals post to social media or use wearable devices\, data generated through these everyday interactions with technology reveal a great deal about behaviors that influence health in ways that were previously not observable. In my work\, I seek to leverage this data to characterize and measure the naturalistic manifestations a.k.a digital phenotyping of mental and physical health. \nIn this talk\, we will look at a) uncovering linguistic markers of ADHD using self-declared statuses on Twitter\, b) scaling language-based user-level questionnaire-estimated psychological stress predictions to communities\, and c) forecasting healthcare utilization as documented in the medical records of a sample of patients using their Facebook posts. Across these studies\, I argue that user generated data is a source of collateral information that can augment clinical practice and potentially guide interventions. URL:https://seasevents.nmsdev7.com/event/cis-seminar-user-generated-content-opportunities-to-inform-healthcare/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200213T120000 DTEND;TZID=America/New_York:20200213T130000 DTSTAMP:20260408T055616 CREATED:20200109T164002Z LAST-MODIFIED:20200109T164002Z UID:10006368-1581595200-1581598800@seasevents.nmsdev7.com SUMMARY:BE Seminar: "Repurposing bacterial two-component systems as sensors for synthetic biology applications " DESCRIPTION:Two-component systems (TCSs) are the largest family of signal transduction pathways in biology\, and a treasure trove of biosensors for engineering applications. Though present in plants and other eukaryotes\, TCSs are ubiquitous in bacteria. Bacteria use TCSs to sense everything from metal ions to carbohydrates and light\, and activate responses such as biofilm formation\, antibiotic-resistance\, and virulence. Despite their importance\, the vast majority of TCSs remain uncharacterized. The major challenges are that most bacteria cannot be cultured nor genetically manipulated in the laboratory\, and that many TCSs are silenced by poorly-understood gene regulatory networks in laboratory conditions. We have recently developed synthetic biology technologies to address these challenges. In particular\, we have developed dual inducible promoter systems that allow us simultaneously express both TCS proteins to optimal levels in the model Gram-negative and Gram-positive bacteria E. coli and B. subtilis. In addition\, we have developed a method to modularly interchange the DNA-binding domains of response regulator proteins\, enabling unknown or silent TCS output promoters to be replaced with well-characterized alternatives. Finally\, we have developed a method to rationally tune the amount of input signal required to activate a TCS over several orders of magnitude by introducing mutations that specifically alter the intrinsic phosphatase activity of the sensor histidine kinase protein. Using these methods\, we have repurposed cyanobacterial TCSs to function as optogenetic tools with wavelength specificities from the ultraviolet (380 nm) to the near infrared (770 nm)\, engineered gut bacteria that diagnose colon inflammation in mice\, and discovered a novel pH-sensing TCS in the genome of Yersinia pestis\, the causative agent of bubonic plague. Additionally\, we have constructed a library of >500 uncharacterized TCSs from the human gut microbiome\, which we are screening for novel sensors of gut metabolites and diseases in humans. Finally\, we are using our methods to develop new anti-virulence compounds that inhibit TCSs that regulate pathogenesis in major human pathogens. Our work is accelerating fundamental microbiological discoveries and has broad applications in synthetic biology. URL:https://seasevents.nmsdev7.com/event/be-seminar-title-tbc-4/ LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Bioengineering":MAILTO:be@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200213T110000 DTEND;TZID=America/New_York:20200213T120000 DTSTAMP:20260408T055616 CREATED:20200206T221336Z LAST-MODIFIED:20200206T221336Z UID:10006401-1581591600-1581595200@seasevents.nmsdev7.com SUMMARY:ESE Seminar: "Adapting black-box machine learning methods for causal inference" DESCRIPTION:Abstract: I’ll discuss the use of observational data to estimate the causal effect of a treatment on an outcome. This task is complicated by the presence of ‘confounders’ that influence both treatment and outcome\, inducing observed associations that are not causal. Causal estimation is achieved by adjusting for this confounding by using observed covariate information. I’ll discuss the case where we observe covariates that carry sufficient information for the adjustment\, but where explicit models relating treatment\, outcome\, covariates\, and confounding are not available. For example\, in medical data the covariates might consist of a large number of convenience health measurements of which only an unknown subset are relevant\, and even then in some totally unknown manner. Or\, the covariates might be a passage of (natural language) text that describes the relevant information. I’ll describe an approach that adapts deep learning and embedding methods to produce representations of the covariate information targeted toward the causal adjustment problem. In particular\, I’ll describe how to modify standard architectures and training objectives to achieve statistically efficient and practically useful causal estimates. URL:https://seasevents.nmsdev7.com/event/ese-seminar-adapting-black-box-machine-learning-methods-for-causal-inference/ LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Colloquium ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200213T104500 DTEND;TZID=America/New_York:20200213T114500 DTSTAMP:20260408T055616 CREATED:20200207T155517Z LAST-MODIFIED:20200207T155517Z UID:10006402-1581590700-1581594300@seasevents.nmsdev7.com SUMMARY:MSE Faculty Candidate Seminar: “Engineering non-equilibrium structure and functionality in complex solids” DESCRIPTION:Unique macroscopic phenomena\, such as high-temperature superconductivity and colossal magnetoresistance\, emerge in many complex solids due to the interplay between their electronic\, magnetic\, and structural degrees of freedom. This interplay also results in properties that can be tuned by manipulating their atomic structure and symmetry. In this talk\, Dr. Disa will discuss two complementary “non-equilibrium” pathways for inducing and influencing functionalities of complex oxides: atomic layer engineering and optical lattice control. \nFirst\, Dr. Disa will describe the control of electronic structure and transport properties of complex oxides through atomically-precise control of dimensionality and interfacial structure using molecular beam epitaxy. Specifically\, he will show how picoscale engineering of atomic distortions is used to design the conductivity and the orbital configuration in rare-earth nickelates. Second\, he will show that resonantly driving optical phonons with terahertz-frequency pulses allows one to engineer structural distortions dynamically\, thus providing a pathway to control electronic and magnetic behavior on ultrafast time scales and even beyond statically possible. Dr. Disa will focus on a recent experiment demonstrating the formation of a metastable ferroelectric state in the common substrate material SrTiO3\, which has a polarization that persists for hours after the optical excitation. \nThese approaches can work in tandem to enable the rational design of non-equilibrium functional properties in complex solids\, which can be exploited for novel\, high-speed optoelectronic and optomagnetic technologies. URL:https://seasevents.nmsdev7.com/event/mse-faculty-candidate-seminar-engineering-non-equilibrium-structure-and-functionality-in-complex-solids/ LOCATION:Auditorium\, LRSM Building\, 3231 Walnut Street\, Philadelphia\, PA\, 19104\, United States ORGANIZER;CN="Materials Science and Engineering":MAILTO:johnruss@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200212T150000 DTEND;TZID=America/New_York:20200212T160000 DTSTAMP:20260408T055616 CREATED:20191219T202706Z LAST-MODIFIED:20191219T202706Z UID:10006352-1581519600-1581523200@seasevents.nmsdev7.com SUMMARY:CBE Seminar: "A Case for Carbon Dioxide Removal from Air" DESCRIPTION:Abstract: \nAs a global society\, we have been burning fossil fuels to meet our energy and transportation needs since the start of the industrial revolution. This has resulted in atmospheric CO2 concentrations much greater than at any other time during the last 650\,000 years. That concentration reached a record 415 parts per million in May 2019. The replacement of fossil fuels with renewables\, advances in energy efficiency\, and carbon capture and storage are among the key strategies required to prevent warming beyond 2°C within this century. But they will not be enough. We need to ramp up our efforts in reducing CO2 emissions\, and then we need to do even more. The Earth’s natural systems\, such as forests and oceans\, are capable of removing roughly half of global CO2 emissions each year\, while the rest steadily accumulates in the atmosphere. Until now\, our best approach to avoiding the worst impacts of climate change was simply to avoid such emissions in the first place. But because of our failure to act quickly and at a large enough scale\, we are now faced with the need to go beyond that strategy—to actually start removing CO2 directly from the air. Trees and oceans already do this\, but these systems are overwhelmed. Manufactured or synthetic removal systems are designed to pull CO2 from the atmosphere\, and at a much faster rate than natural systems. This talk will review both the promise and pitfalls of this approach. URL:https://seasevents.nmsdev7.com/event/cbe-seminar-a-case-for-carbon-dioxide-removal-from-air/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200211T150000 DTEND;TZID=America/New_York:20200211T160000 DTSTAMP:20260408T055616 CREATED:20200205T174219Z LAST-MODIFIED:20200205T174219Z UID:10006399-1581433200-1581436800@seasevents.nmsdev7.com SUMMARY:CIS Seminar: Rethinking Operating System and Hardware Abstractions for Good and Evil DESCRIPTION:Abstract:\n\nCurrent hardware and operating system abstractions were conceived at a time when we had minimal security threats\, scarce compute and memory resources\, and limited numbers of users. These assumptions are not true today. On one hand\, attacks such as Spectre and Meltdown have shown that current hardware is plagued by vulnerabilities. On the other hand\, new emerging cloud paradigms like microservices and serverless computing have led to the sharing of computing resources among hundreds of users at a time. In this new era of computing\, we can no longer afford to build each layer separately. Instead\, we have to rethink the synergy between the operating system and hardware from the ground up.\n\nIn this talk\, I will focus on rethinking the virtual memory abstraction. First\, I will introduce Microarchitectural Replay Attacks\, a novel family of side-channel attacks that exploit existing virtual memory mechanisms. These attacks leverage the fact that\, in modern out-of-order processors\, a single dynamic instruction can be forced to execute many times. Then\, I will describe Elastic Cuckoo Page Tables\, my proposal to rebuild the virtual memory abstraction for parallelism. Finally\, I will conclude by describing ongoing and future directions towards redesigning the hardware and the operating system layers. URL:https://seasevents.nmsdev7.com/event/cis-seminar-rethinking-operating-system-and-hardware-abstractions-for-good-and-evil/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Colloquium ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200211T110000 DTEND;TZID=America/New_York:20200211T120000 DTSTAMP:20260408T055616 CREATED:20200206T180607Z LAST-MODIFIED:20200206T180607Z UID:10006400-1581418800-1581422400@seasevents.nmsdev7.com SUMMARY:ESE Seminar: "Large-Scale Quantum Photonic Processors" DESCRIPTION:Abstract\nPhotons play a central role in many areas of quantum information science\, either as qubit themselves or to mediate interactions between long-lived matter based qubits. Techniques for (1) high-fidelity generation\, (2) precise manipulation and (3) ultra-efficient detection of quantum states of light are therefore a prerequisite for virtually all quantum technologies. A quantum photonic processor is the union of these three core technologies into a single system\, and\, bolstered by advances in integrated photonics\, promises to be a versatile platform for quantum information science. In this talk we present recent progress towards large-scale quantum photonic processors and demonstrate how such systems enable new applications at the nexus of quantum mechanics and machine learning. URL:https://seasevents.nmsdev7.com/event/ese-seminar-large-scale-quantum-photonic-processors/ LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Colloquium ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200211T103000 DTEND;TZID=America/New_York:20200211T120000 DTSTAMP:20260408T055616 CREATED:20200108T213156Z LAST-MODIFIED:20200108T213156Z UID:10006362-1581417000-1581422400@seasevents.nmsdev7.com SUMMARY:MEAM Seminar: "Recent Evolution of Climate Science: From Greenhouse Gases and Temperature to Aerosol Particles and Precipitation" DESCRIPTION:On the eve of the Intergovermental Panel on Climate Change (IPCC) Sixth Assessment Report\, I will present a brief overview of how climate science has evolved since the publication of the Charney Report in 1979\, and use a few examples from my recent work to show how one can use numerical models\, observations and theories to advance the fundamental understanding of Earth’s climate system. URL:https://seasevents.nmsdev7.com/event/meam-seminar-recent-evolution-of-climate-science-from-greenhouse-gases-and-temperature-to-aerosol-particles-and-precipitation/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200210T150000 DTEND;TZID=America/New_York:20200210T160000 DTSTAMP:20260408T055616 CREATED:20191220T195149Z LAST-MODIFIED:20191220T195149Z UID:10006358-1581346800-1581350400@seasevents.nmsdev7.com SUMMARY:CBE Faculty Candidate Seminar: "Facilitating Chemical Process Development Using Theoretical Modeling and Machine Learning" DESCRIPTION:Abstract: \nComputational modeling is an important tool to aid chemical process development. Theoretical and data-driven models can be applied both for the optimization of specific processes\, and for the initial screening of potential process chemistries. I will talk about my research in advancing both of these areas. First\, I will introduce the development of an efficient kinetic Monte Carlo simulation to facilitate property optimization of polymer materials. The algorithm predicts the explicit sequence distribution of the polymer chains and can be used to design reaction recipe for desired molecular weight and sequence properties of synthetic polymers. Second\, I will discuss the use of machine learning in the context of organic synthesis planning. Specifically\, I developed an algorithm capable of efficiently and accurately recommending reaction conditions\, including catalysts\, solvents\, reagents and temperature\, for organic synthesis development. I will also demonstrate how we can leverage this information to optimize synthesis plans for individual molecules or molecular libraries. URL:https://seasevents.nmsdev7.com/event/cbe-seminar-facilitating-chemical-process-development-using-theoretical-modeling-and-machine-learning/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200210T120000 DTEND;TZID=America/New_York:20200210T130000 DTSTAMP:20260408T055616 CREATED:20200109T172158Z LAST-MODIFIED:20200109T172158Z UID:10006369-1581336000-1581339600@seasevents.nmsdev7.com SUMMARY:PSOC Seminar : “ Programming bacteria as a cancer therapy” DESCRIPTION: URL:https://seasevents.nmsdev7.com/event/psoc-seminar-programming-bacteria-as-a-cancer-therapy/ LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States ORGANIZER;CN="PSOC":MAILTO:manu@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200207T160000 DTEND;TZID=America/New_York:20200207T170000 DTSTAMP:20260408T055616 CREATED:20200129T192625Z LAST-MODIFIED:20200129T192625Z UID:10006392-1581091200-1581094800@seasevents.nmsdev7.com SUMMARY:The Joy of Being Faculty PT I: How to Interview for a Faculty Position DESCRIPTION:This professional development workshop series is designed to provide Penn Engineering graduate students and postdocs with a richer understanding of what it is like to pursue a career in academia from those that have navigated the process successfully. Deputy Dean Kathleen J. Stebe (SEAS) will lead this extemporaneous discussion with a panel of Penn Engineering professors. Networking reception to follow. URL:https://seasevents.nmsdev7.com/event/the-joy-of-being-faculty-pt-i-how-to-interview-for-a-faculty-position/ LOCATION:Heilmeier Hall (Room 100)\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Doctoral,Graduate,Panel Discussion,Postdoctoral END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200206T150000 DTEND;TZID=America/New_York:20200206T160000 DTSTAMP:20260408T055616 CREATED:20200131T143450Z LAST-MODIFIED:20200131T143450Z UID:10006395-1581001200-1581004800@seasevents.nmsdev7.com SUMMARY:ESE & CIS Seminar: "Toward Power-Efficient Computing with Applied Inference" DESCRIPTION:Abstract: We require computers that extract value from exponential data growth even as exponential transistor scaling falters. With limited scaling\, power and thermal density threaten performance. Architects must pursue power efficiency in design and management. My research group addresses these challenges by integrating systems architecture with statistical inference. First\, we design systems by tailoring hardware to software. We construct statistical surrogates for expensive design tools\, solving previously intractable problems in heterogeneous\, adaptive\, and specialized processing. Second\, we manage systems by allocating datacenter power. We construct multi-agent games and discover statistical equilibria in which users draw power strategically and avoid oversubscribing shared power. Third\, we diagnose system anomalies by inferring causal performance models and extracting themes from these models with semantic clustering. Finally\, we will discuss future directions for efficient computing in datacenters and beyond. URL:https://seasevents.nmsdev7.com/event/ese-cis-seminar-benjamin-lee/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Colloquium ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200206T120000 DTEND;TZID=America/New_York:20200206T130000 DTSTAMP:20260408T055616 CREATED:20191210T195611Z LAST-MODIFIED:20191210T195611Z UID:10006345-1580990400-1580994000@seasevents.nmsdev7.com SUMMARY:BE Seminar: "Immunomodulatory Biomaterials for Limb Salvage" DESCRIPTION:Diabetes and peripheral arterial disease affect hundreds of millions of people worldwide. Patients with these conditions frequently develop chronic wounds on the lower limbs that lead to amputation\, with a 5-year mortality rate as high as 77%. Macrophages\, the primary cell of the innate immune system\, are critical regulators of angiogenesis and wound healing. Their dysfunction is strongly implicated in arterial dysfunction\, limb ischemia\, and poorly healing chronic wounds. The goal of the Biomaterials and Regenerative Medicine Laboratory at Drexel University is to understand the mechanisms by which macrophages orchestrate successful angiogenesis and tissue regeneration and to develop novel biomaterial strategies that apply these principles to pathological situations\, in order to ultimately prevent limb amputation. This talk will focus on the effects of temporal changes in macrophage phenotype on angiogenesis\, the design of biomaterials and drug delivery systems to modulate macrophage phenotype for enhanced angiogenesis\, and the development of macrophage phenotype-related biomarkers to assist in clinical decision making for a personalized medicine approach to wound care. URL:https://seasevents.nmsdev7.com/event/be-seminar-immunomodulatory-biomaterials-for-limb-salvage/ LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Bioengineering":MAILTO:be@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200206T104500 DTEND;TZID=America/New_York:20200206T114500 DTSTAMP:20260408T055616 CREATED:20200131T195606Z LAST-MODIFIED:20200131T195606Z UID:10006396-1580985900-1580989500@seasevents.nmsdev7.com SUMMARY:MSE Faculty Candidate Seminar: “Atomically Thin Films and Superlattices” DESCRIPTION:Thin film materials and heterostructures play a key role in modern technology including electronics and photonics. Atomically precise engineering of thin film materials enables unprecedented control of their structure and properties\, bringing exciting opportunities to materials science. Transition metal dichalcogenides (TMDs)\, which form three-atom-thick monolayers with van der Waals surfaces\, provide an ideal material platform with diverse electrical and optical properties for thin film engineering in the atomically thin limit. \nIn this talk\, Dr. Xie will discuss three key synthesis challenges for realizing atomically engineered thin films and superlattices with atomically thin TMDs. Firstly\, he will discuss how high-performance monolayer TMD films can be synthesized with wafer-scale uniformity. Furthermore\, he will discuss how dissimilar TMDs (e.g. tungsten disulfide and tungsten diselenide) can be integrated laterally in the monolayer plane to form superlattices without dislocations\, despite a large 4% lattice mismatch. Lastly\, Dr. Xie will discuss how various TMD monolayers can be stacked vertically to form programmed van der Waals superlattices. These scalable synthesis capabilities will further enable novel atomically engineered materials that hold great potential for future ultrathin electronics. URL:https://seasevents.nmsdev7.com/event/mse-faculty-candidate-seminar-atomically-thin-films-and-superlattices/ LOCATION:Auditorium\, LRSM Building\, 3231 Walnut Street\, Philadelphia\, PA\, 19104\, United States ORGANIZER;CN="Materials Science and Engineering":MAILTO:johnruss@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200205T150000 DTEND;TZID=America/New_York:20200205T160000 DTSTAMP:20260408T055616 CREATED:20191219T200822Z LAST-MODIFIED:20191219T200822Z UID:10006350-1580914800-1580918400@seasevents.nmsdev7.com SUMMARY:CBE Faculty Candidate Seminar: "Understanding and Controlling the Complexity of Catalytic Active Sites" DESCRIPTION:Abstract:\nHeterogeneous catalysis is of central importance to the global economy today\, facilitating the conversion of raw materials into valuable fuels and chemicals\, and the abatement of chemical pollutants in an efficient way. As environmental concerns associated with the use of fossil fuels and increased viability of alternative technologies motivate a transition away from traditional chemical processes\, continued development and understanding of catalytic reactions will be of vital importance. At the atomic level\, catalytic reactions involve the making and breaking of chemical bonds between reacting molecules and active sites.  As our understanding of catalytic reactions advances\, it has become apparent that the environment in which active sites operate can significantly impact reactivity\, both by influencing the structure of these active sites\, and by directly affecting reaction energetics. Appreciation of the dynamic behavior of active sites and the influence of the reaction environment on catalysis is therefore required for a full description of a catalytic process\, and once understood\, can provide additional tools for designing catalysts. Control over both the binding site and the non-reactive components in its vicinity can lead to optimal activity\, as elegantly demonstrated by nature’s catalysts\, enzymes. In this talk\, two illustrative examples are provided that demonstrate the consequences of the reaction environment surrounding an active site on catalyst structure and reactivity. \n  URL:https://seasevents.nmsdev7.com/event/cbe-seminar-understanding-and-controlling-the-complexity-of-catalytic-active-sites/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200204T104500 DTEND;TZID=America/New_York:20200204T114500 DTSTAMP:20260408T055616 CREATED:20200122T150914Z LAST-MODIFIED:20200122T150914Z UID:10006386-1580813100-1580816700@seasevents.nmsdev7.com SUMMARY:MSE Faculty Candidate Seminar: "Unsupervised Learning of Dislocation Motion" DESCRIPTION:High-performance designs that utilize metallic alloys are driving a need to quantify deformation in-situ at the finest length scales in order to reduce weight\, increase operating temperatures\, and improve fatigue life. With improvements to data reconstruction algorithms\, brighter X-ray sources\, and more efficient detectors\, these in-situ studies of microstructural and micromechanical evolution in 3-D (nm-µm length scales) and at rapid time scales (