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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220420T153000
DTEND;TZID=America/New_York:20220420T163000
DTSTAMP:20260406T073451
CREATED:20220115T005720Z
LAST-MODIFIED:20220115T005720Z
UID:10007020-1650468600-1650472200@seasevents.nmsdev7.com
SUMMARY:CBE Seminar: "Design of Advanced Functional Surfaces Using Oxygen-Tolerant Photopolymerization”
DESCRIPTION:Abstract \nThe covalent attachment of polymers has emerged as a powerful strategy for the preparation of multi-functional surfaces. Patterned\, surface-grafted polymer brushes provide spatial control over a variety of physical properties and allow for fabrication of ‘intelligent’ substrates which selectively adapt to their environment. This presentation describes recent advances in our group in using photolithography to produce topographically and chemically-patterned polymer brush surfaces via surface-initiated (SI) photoinduced electron/energy transfer (PET) reversible addition–fragmentation chain transfer (RAFT) polymerization. Using this oxygen tolerant approach\, organic light emitting diodes (OLEDs)\, anti-microbial surfaces\, and anti-fogging coatings are engineered to highlight facile pathways towards advanced functional surfaces. Oxygen tolerance\, mild reaction conditions\, and the use of visible light make this approach user-friendly in its application for the design of patterned and functional organic thin films.
URL:https://seasevents.nmsdev7.com/event/cbe-seminar-design-of-advanced-functional-surfaces-using-oxygen-tolerant-photopolymerization/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220420T150000
DTEND;TZID=America/New_York:20220420T160000
DTSTAMP:20260406T073451
CREATED:20220405T133516Z
LAST-MODIFIED:20220405T133516Z
UID:10007151-1650466800-1650470400@seasevents.nmsdev7.com
SUMMARY:Spring 2022 GRASP SFI: Stefanie Tellex\, Brown University\, “Towards Complex Language in Partially Observed Environments”
DESCRIPTION:*This will be a HYBRID Event with in-person attendance in Levine 512 and Virtual attendance via Zoom \nRobots can act as a force multiplier for people\, whether a robot assisting an astronaut with a repair on the International Space station\, a UAV taking flight over our cities\, or an autonomous vehicle driving through our streets. Existing approaches use action-based representations that do not capture the goal-based meaning of a language expression and do not generalize to partially observed environments. The aim of my research program is to create autonomous robots that can understand complex goal-based commands and execute those commands in partially observed\, dynamic environments. I will describe demonstrations of object-search in a POMDP setting with information about object locations provided by language\, and mapping between English and Linear Temporal Logic\, enabling a robot to understand complex natural language commands in city-scale environments. These advances represent steps towards robots that interpret complex natural language commands in partially observed environments using a decision theoretic framework.
URL:https://seasevents.nmsdev7.com/event/spring-2022-grasp-sfi-stefanie-tellex-brown-university-towards-complex-language-in-partially-observed-environments/
LOCATION:Levine 512
ORGANIZER;CN="General Robotics%2C Automation%2C Sensing and Perception (GRASP) Lab":MAILTO:grasplab@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220420T130000
DTEND;TZID=America/New_York:20220420T150000
DTSTAMP:20260406T073451
CREATED:20220404T181409Z
LAST-MODIFIED:20220404T181409Z
UID:10007150-1650459600-1650466800@seasevents.nmsdev7.com
SUMMARY:BE Doctoral Dissertation Defense: "Biglycan regulation of regional tendon development via the pericellular matrix" (Ryan Leiphart)
DESCRIPTION:The Department of Bioengineering at the University of Pennsylvania and Dr. Louis Soslowsky are pleased to announce the Doctoral Dissertation Defense of Ryan Leiphart\n\nTitle: Biglycan regulation of regional tendon development via the pericellular matrix\n\nDate: Wednesday\, April 20th\nTime: 1PM\nLocation: JMB Reunion Auditorium\nJohn Morgan Building\n3620 Hamilton Walk\nPhiladelphia\, PA 19104\n \nZoom Link: https://upenn.zoom.us/j/94685018569?pwd=WnNRMmYrUzZtcm1Wd1JoVVF1TENBUT09\nPassword: embiid\n\nThe public is welcome to attend.
URL:https://seasevents.nmsdev7.com/event/be-doctoral-dissertation-defense-biglycan-regulation-of-regional-tendon-development-via-the-pericellular-matrix-ryan-leiphart/
LOCATION:JMB Reunion Auditorium\, 3620 Hamilton Walk\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Doctoral,Graduate,Student,Dissertation or Thesis Defense
ORGANIZER;CN="Bioengineering":MAILTO:be@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220420T130000
DTEND;TZID=America/New_York:20220420T140000
DTSTAMP:20260406T073451
CREATED:20220414T182100Z
LAST-MODIFIED:20220414T182100Z
UID:10007161-1650459600-1650463200@seasevents.nmsdev7.com
SUMMARY:Cobb's Creek Tour
DESCRIPTION:Please use the link below to find more information and sign up for the tour! \nhttps://docs.google.com/forms/d/e/1FAIpQLSc-OxodC7fsVFL7AMX_gK4gblHO8zPw5IaZRE-15wUXTUnVRg/viewform
URL:https://seasevents.nmsdev7.com/event/cobbs-creek-tour/
LOCATION:700 Cobbs Creek Parkway\, Philadelphia\, PA 19134\, 700 Cobbs Creek Parkway\, Philadelphia\, PA\, 19134\, United States
ATTACH;FMTTYPE=image/jpeg:https://seasevents.nmsdev7.com/wp-content/uploads/2022/04/CCCECTour-copy1-scaled-1.jpg
ORGANIZER;CN="SEAS Green Team":MAILTO:dianepa@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220420T110000
DTEND;TZID=America/New_York:20220420T120000
DTSTAMP:20260406T073451
CREATED:20220110T152828Z
LAST-MODIFIED:20220110T152828Z
UID:10007003-1650452400-1650456000@seasevents.nmsdev7.com
SUMMARY:CEMB Future Leaders: "Plant homologs of PIEZO mechanosensitive ion channels localize to the tonoplast and affect vacuolar morphology"
DESCRIPTION:Launched in May 2021\, the Future Leaders in Mechanobiology is a monthly seminar series featuring up-and-coming leaders in mechanobiology–PhD students and postdocs from a wide range of fields\, backgrounds\, and institutions. By providing an international stage to share one’s work and opportunities to interact with researchers at all career stages\, we aim to create an inclusive and valuable series for early-stage researchers and the mechanobiology community as a whole. \nRegister HERE for access to the Zoom link and visit the CEMB website for more information.
URL:https://seasevents.nmsdev7.com/event/cemb-future-leaders-plant-homologs-of-piezo-mechanosensitive-ion-channels-localize-to-the-tonoplast-and-affect-vacuolar-morphology/
LOCATION:https://upenn.zoom.us/j/96715197752
ORGANIZER;CN="Center for Engineering MechanoBiology (CEMB)":MAILTO:annjeong@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220419T150000
DTEND;TZID=America/New_York:20220419T170000
DTSTAMP:20260406T073451
CREATED:20220412T192214Z
LAST-MODIFIED:20220412T192214Z
UID:10007159-1650380400-1650387600@seasevents.nmsdev7.com
SUMMARY:ESE Ph.D. Thesis Defense: "Extracting Generalizable Hierarchical Patterns of Functional Connectivity in the Brain"
DESCRIPTION:The study of the functional organization of the human brain using resting-state functional MRI (rsfMRI) has been of significant interest in cognitive neuroscience for over two decades. The functional organization is characterized by patterns that are believed to be hierarchical in nature. From a clinical context\, studying these patterns has become important for understanding various disorders such as Major Depressive Disorder\, Autism\, Schizophrenia\, etc. However\, extraction of these interpretable patterns might face challenges in multi-site rsfMRI studies due to variability introduced due to confounding variability introduced by different sites and scanners. This can reduce the predictive power and reproducibility of the patterns\, affecting the confidence in using these patterns as biomarkers for assessing and predicting disease. In this thesis\, we focus on the problem of robustly extracting hierarchical patterns that can be used as biomarkers for diseases. \nWe propose a matrix factorization based method to extract interpretable hierarchical decomposition of the rsfRMI data. We couple the method with adversarial learning to improve inter-site robustness in multi-site studies\, removing non-biological variability that can result in less interpretable and discriminative biomarkers. Finally\, a generative-discriminative model is built on top of the proposed framework to extract robust patterns/biomarkers characterizing Major Depressive Disorder. \nResults on large multi-site rsfMRI studies show the effectiveness of our method in uncovering reproducible connectivity patterns across individuals with high predictive power while maintaining clinical interpretability. Our framework robustly identifies brain patterns characterizing MDD and provides an understanding of the manifestation of the disorder from a functional networks perspective which can be crucial for effective diagnosis\, treatment and prevention. The results demonstrate the method’s utility and facilitate a broader understanding of the human brain from a functional perspective.
URL:https://seasevents.nmsdev7.com/event/ese-ph-d-thesis-defense-extracting-generalizable-hierarchical-patterns-of-functional-connectivity-in-the-brain/
LOCATION:Levine 307\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Dissertation or Thesis Defense
ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220419T100000
DTEND;TZID=America/New_York:20220419T140000
DTSTAMP:20260406T073451
CREATED:20220414T180629Z
LAST-MODIFIED:20220414T180629Z
UID:10007160-1650362400-1650376800@seasevents.nmsdev7.com
SUMMARY:SEAS Green Team Book Swap & E-Waste Collection
DESCRIPTION:
URL:https://seasevents.nmsdev7.com/event/seas-green-team-book-swap-e-waste-collection/
LOCATION:Lobby and Mezzanine\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
ATTACH;FMTTYPE=image/jpeg:https://seasevents.nmsdev7.com/wp-content/uploads/2022/04/2022-Book-Swap-Drop-Bin-scaled-1.jpg
ORGANIZER;CN="SEAS Green Team":MAILTO:dianepa@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220419T100000
DTEND;TZID=America/New_York:20220419T113000
DTSTAMP:20260406T073451
CREATED:20220407T180040Z
LAST-MODIFIED:20220407T180040Z
UID:10007155-1650362400-1650367800@seasevents.nmsdev7.com
SUMMARY:Tedori-Callinan Distinguished Lecture: "Multiscale Hierarchical Modeling and Thermal Management of Electrification Technologies"
DESCRIPTION:Core electrification technologies require developments in battery packs\, chargers\, electric motors\, and thermal management strategies to improve their performance\, longevity\, reliability and safety. The next battery technology leap relies on novel thermal management strategies and packaging architectures\, realized as intelligent battery thermal management systems (BTMS)\, which can optimally control the thermo-electrochemical phenomena occurring inside the batteries to maximize performance\, minimize degradation\, enable fast-charging protocols\, and accelerate a seamless transition of degraded electric vehicle (EV) batteries into less-demanding second-life stationary systems. This Lecture will present current engineering challenges and opportunities on EV thermal management\, with a focus on our research on multiscale hierarchical design\, modelling\, and optimization approaches to overcome cooling and heating challenges across multiple physical domains and length scales\, from battery electrodes\, to battery cells\, battery packs\, to EV thermal management systems.
URL:https://seasevents.nmsdev7.com/event/tedori-callinan-distinguished-lecture-multiscale-hierarchical-modeling-and-thermal-management-of-electrification-technologies/
LOCATION:Zoom – Email MEAM for Link\, peterlit@seas.upenn.edu
CATEGORIES:Distinguished Lecture
ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220418T120000
DTEND;TZID=America/New_York:20220418T130000
DTSTAMP:20260406T073451
CREATED:20220207T143857Z
LAST-MODIFIED:20220207T143857Z
UID:10007070-1650283200-1650286800@seasevents.nmsdev7.com
SUMMARY:PSOC@Penn Seminar
DESCRIPTION:Physical Sciences in Oncology Center PSOC@Penn \nSpring 2022 Hybrid-Seminar Series \nTowne 225 / Raisler Lounge @ Noon (EST) \nFor Zoom link \, please contact manu@seas.upenn.edu
URL:https://seasevents.nmsdev7.com/event/psocpenn-seminar/
LOCATION:Raisler Lounge (Room 225)\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="PSOC":MAILTO:manu@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220415T140000
DTEND;TZID=America/New_York:20220415T150000
DTSTAMP:20260406T073451
CREATED:20220301T140452Z
LAST-MODIFIED:20220301T140452Z
UID:10007105-1650031200-1650034800@seasevents.nmsdev7.com
SUMMARY:PICS Colloquium: "Transforming Healthcare from the Outside: the OBSERVER project"
DESCRIPTION:We live with a health care system that has evolved into an increasingly fragmented\, primarily treatment-oriented\, and now heavily burdened environment.  More importantly\, issues related to privacy\, space\, and disease transmissibility have limited access to non-medical personnel who might offer creative\, evidence-based\, radical change to the health care system\, as proposed years ago by the National Research Council.  One way to reimagine that access is through the use of multimodal digital data that summarize patient encounters and make them amenable to outside observers. This talk with summarize the rationale for this project and offer a framework for thinking through how the OBSERVER project could be realized.
URL:https://seasevents.nmsdev7.com/event/pics-colloquium-transforming-healthcare-from-the-outside-the-observer-project/
LOCATION:PICS Conference Room 534 – A Wing \, 5th Floor\, 3401 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Colloquium
ORGANIZER;CN="Penn Institute for Computational Science (PICS)":MAILTO:dkparks@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220415T110000
DTEND;TZID=America/New_York:20220415T130000
DTSTAMP:20260406T073451
CREATED:20220328T150441Z
LAST-MODIFIED:20220328T150441Z
UID:10007134-1650020400-1650027600@seasevents.nmsdev7.com
SUMMARY:BE Doctoral Dissertation Defense: "Leveraging Macrophage Immune Checkpoint Blockade to Link Innate and Adaptive Immunity Against Solid Tumors" (Jason Andrechak)
DESCRIPTION:The Department of Bioengineering at the University of Pennsylvania and Dr. Dennis Discher are pleased to announce the Doctoral Dissertation Defense of Jason Andrechak.\n \nTitle: Leveraging Macrophage Immune Checkpoint Blockade to Link Innate and Adaptive Immunity Against Solid Tumors\n\n\nDate/time: Friday\, 4/15 at 11am\nLocation: Glandt Forum\nSingh Center for Nanotechnology\n3205 Walnut St\, Philadelphia\, PA 19104\n\nIt will be hybrid:\nZoom link: https://upenn.zoom.us/j/96831196783?pwd=bExOUWFFbTRLYWM1Sy9JMzdNTldoQT09\n\nPassword: macrophage\n\n\n\n\nThe public is welcome to attend.
URL:https://seasevents.nmsdev7.com/event/be-doctoral-dissertation-defense-leveraging-macrophage-immune-checkpoint-blockade-to-link-innate-and-adaptive-immunity-against-solid-tumors-jason-andrechak/
LOCATION:Glandt Forum\, Singh Center for Nanotechnology\, 3205 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Doctoral,Graduate,Student,Dissertation or Thesis Defense
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220415T103000
DTEND;TZID=America/New_York:20220415T114500
DTSTAMP:20260406T073451
CREATED:20220328T200141Z
LAST-MODIFIED:20220328T200141Z
UID:10007135-1650018600-1650023100@seasevents.nmsdev7.com
SUMMARY:GRASP on Robotics: Vincent Sitzmann\, Massachusetts Institute of Technology\, “Self-supervised Scene Representation Learning for Robotics”
DESCRIPTION:Given only a single picture\, people are capable of inferring a mental representation that encodes rich information about the underlying 3D scene. We acquire this skill not through massive labeled datasets of 3D scenes\, but through self-supervised observation and interaction. Building machines that can infer similarly rich neural scene representations is critical if they are to one day parallel people’s ability to understand\, navigate\, and interact with their surroundings. In this talk\, I will demonstrate how we can equip neural networks with inductive biases that enable them to learn 3D geometry\, appearance\, and even semantic information\, self-supervised only from posed images. I will show how this approach unlocks the learning of priors\, enabling 3D reconstruction from only a single posed 2D image. I will then talk about a recent application of self-supervised scene representation learning in robotic manipulation\, where it enables us to learn to manipulate classes of objects in unseen poses from only a handful of human demonstrations\, as well as the application of neural rendering to learn latent spaces amenable to control. I will then discuss recent work on learning the neural rendering operator to make rendering and training fast\, and how this speed-up enables us to learn object-centric neural scene representations\, learning to decompose 3D scenes into objects\, given only images. Finally\, I will discuss how neural scene representations may offer a new angle to tackle challenges in robotics.
URL:https://seasevents.nmsdev7.com/event/grasp-on-robotics-vincent-sitzmann-massachusetts-institute-of-technology-self-supervised-scene-representation-learning-for-robotics/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
ORGANIZER;CN="General Robotics%2C Automation%2C Sensing and Perception (GRASP) Lab":MAILTO:grasplab@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220414T133000
DTEND;TZID=America/New_York:20220414T143000
DTSTAMP:20260406T073451
CREATED:20220401T143714Z
LAST-MODIFIED:20220401T143714Z
UID:10007145-1649943000-1649946600@seasevents.nmsdev7.com
SUMMARY:MEAM Seminar: "Exploiting Environmental Fields for Orienteering and Planning Problems"
DESCRIPTION:Robots are increasingly being used to complete tasks in complex environments. To complete these tasks\, two of the most fundamental choices that the robot must make are (1) task planning: which tasks to complete and in what order\, and (2) path planning: what path to take when navigating between those tasks. In this seminar\, I will consider robots operating in environments where the vehicle dynamics are impacted by the dynamics of the environment (environments with flows) while they complete these tasks. I begin by exploring several limitations of existing strategies that tackle task and path planning in environments with flows as separate problems. First\, I examine a problem that focuses on the high level problem of task planning\, but abstracts away the environment and assumes that the low-level path planning work is solved independently. This helps simplify the problem\, but neglects to include environmental information in the problem. In order to address this limitation\, I consider a path planning algorithm in an environment where the flow field can be designed. In particular\, I consider a scenario where a magnetic force field is used to manipulate the flow field. In this case\, I show how a topological approach can be used to take advantage of the structures in the field. Finally\, I examine a scenario where the flow field is determined by ocean currents and therefore cannot be controlled. I will present an integrated solution approach to task and path planning that unifies the two problems in the presence of ocean currents.
URL:https://seasevents.nmsdev7.com/event/meam-seminar-exploiting-environmental-fields-for-orienteering-and-planning-problems/
LOCATION:Zoom – Email MEAM for Link\, peterlit@seas.upenn.edu
CATEGORIES:Seminar,Doctoral
ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220414T103000
DTEND;TZID=America/New_York:20220414T113000
DTSTAMP:20260406T073451
CREATED:20220406T160521Z
LAST-MODIFIED:20220406T160521Z
UID:10007154-1649932200-1649935800@seasevents.nmsdev7.com
SUMMARY:GRASP Special Seminar: Steven Ceron\, Cornell University\, “Swarms Across Length Scales with Local-to-Global Behaviors”
DESCRIPTION:*This will be a HYBRID Event with in-person attendance in Towne 337 and Virtual attendance via Zoom \nCollectives in nature demonstrate behaviors that extend far beyond the capabilities of any single agent. Social slime mold\, for example\, has thousands of cells that aggregate and form mobile and immobile nutrient-searching structures as a function of chemical signals. This species embodies many features that swarm roboticists wish to incorporate in scalable\, self-reconfigurable robot collectives: local-to-global behaviors\, low-level communication\, plasticity\, and simple constituents. I argue that regardless of the length scale\, we can implement some of the same principles and features to exploit robot morphology\, physical interactions among agents\, and low-level coordination mechanisms to enable diverse collective behaviors for useful functions in many fields. I present novel emergent collective behaviors at the macro-scale and micron scale and explain how each behavior arises as a function of agents interacting with other agents\, agents reacting to their environment\, and agents exploiting their environment to affect other agents. Specifically\, I show cell-inspired\, macro-scale soft robot collectives for distributed systems with coupled sensing and actuation\, magnetic microrobot collectives with reconfigurable behaviors and functions for biomedical applications\, and cross-scale coordination mechanisms through virtual swarming coupled oscillators for macro- and micro-scale collective control applications.
URL:https://seasevents.nmsdev7.com/event/grasp-special-seminar-steven-ceron-cornell-university-swarms-across-length-scales-with-local-to-global-behaviors/
LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
ORGANIZER;CN="General Robotics%2C Automation%2C Sensing and Perception (GRASP) Lab":MAILTO:grasplab@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220414T103000
DTEND;TZID=America/New_York:20220414T113000
DTSTAMP:20260406T073451
CREATED:20220322T165141Z
LAST-MODIFIED:20220322T165141Z
UID:10007126-1649932200-1649935800@seasevents.nmsdev7.com
SUMMARY:MSE Seminar: "Role of Solvation and Dynamics on Ion Transport in Polymer Electrolytes"
DESCRIPTION:Polymer electrolytes are an important class of ion conducting materials critical to enabling various electrochemical systems. Fundamentally\, ion-polymer coordination\, inter-connectivity of solvation sites\, and corresponding ion-solvating polymer dynamics are critical in understanding the limits of ionic conductivity. Here\, the importance of these effects is highlighted in a series of combined experimental and computational studies on model lithium-ion conducting polymer electrolytes. First\, we focus on graft polymer architectures of poly[(oligo ethylene oxide) methyl ether methacrylate] (POEM) varying oligo side-chain lengths. With addition of lithium bis(trifluoromethanesulfonyl)imide (LiTFSI)\, the observed differences in ionic conductivity between the POEM derivatives and linear poly(ethylene oxide) (PEO) cannot be adequately explained by differences in Tg. Instead\, graft architecture of POEM leads to nonuniform\, position-dependent relaxation and ion solvation behaviors along the side chain. Importantly\, the limits of ionic conductivity are dictated by the segmental mobility of the ethylene oxide units that form effective solvation sites\, rather than system-wide dynamics. Lastly\, the talk will end with results from ongoing work focusing on solvation site formation and ion transport mechanisms in mixed polarity copolymers based on POEM and poly(glycerol carbonate methacrylate) (PGCMA).
URL:https://seasevents.nmsdev7.com/event/mse-seminar-role-of-solvation-and-dynamics-on-ion-transport-in-polymer-electrolytes/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
ORGANIZER;CN="Materials Science and Engineering":MAILTO:johnruss@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220413T153000
DTEND;TZID=America/New_York:20220413T163000
DTSTAMP:20260406T073451
CREATED:20220115T004856Z
LAST-MODIFIED:20220115T004856Z
UID:10007019-1649863800-1649867400@seasevents.nmsdev7.com
SUMMARY:CBE Seminar: John A. Quinn Distinguished Lecture - "Molecular and Colloidal Interactions in Water”
DESCRIPTION:Abstract \nLife occurs in water\, and water-mediated interactions are central to biomolecular assembly processes.  Synthetic materials as common as soap and shampoo also rely on water-mediated interactions.  This presentation will describe experiments that highlight our lack of understanding of interactions in water.  The opportunity to formulate a refined set of design rules for self-assembly of functional materials in water will be discussed.
URL:https://seasevents.nmsdev7.com/event/cbe-seminar-john-a-quinn-distinguished-lecture-molecular-and-colloidal-interactions-in-water/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar,Distinguished Lecture
ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220413T150000
DTEND;TZID=America/New_York:20220413T160000
DTSTAMP:20260406T073451
CREATED:20220408T195819Z
LAST-MODIFIED:20220408T195819Z
UID:10007157-1649862000-1649865600@seasevents.nmsdev7.com
SUMMARY:Spring 2022 GRASP SFI: Georgios Georgakis\, University of Pennsylvania\, “Cross-modal Map Learning for Vision and Language Navigation”
DESCRIPTION:*This will be a HYBRID Event with in-person attendance in Levine 512 and Virtual attendance via Zoom \nWe consider the problem of Vision-and-Language Navigation (VLN) in previously unseen realistic indoor environments. Arguably\, the biggest challenge in VLN is grounding the natural language to the visual input. The majority of current methods for VLN are trained end-to-end using either unstructured memory such as LSTM\, or using cross-modal attention over the egocentric RGB-D observations of the agent. We are motivated by studies on navigation of biological systems that suggest humans build cognitive maps during such tasks. In contrast to other works\, we argue that an egocentric map offers a more natural representation for this task. In this talk\, we will explore a novel navigation system for the VLN task in continuous environments that learns a language-informed representation for both map and trajectory prediction. This approach semantically grounds the language through an egocentric map prediction task that learns to hallucinate information outside the field-of-view of the agent. This is followed by spatial grounding of the instruction by path prediction on the egocentric map. We experimentally test the basic hypothesis that language-driven navigation can be solved given a map\, and then show competitive results on the full VLN-CE benchmark.
URL:https://seasevents.nmsdev7.com/event/spring-2022-grasp-sfi-georgios-georgakis-university-of-pennsylvania-cross-modal-map-learning-for-vision-and-language-navigation/
LOCATION:Levine 512
ORGANIZER;CN="General Robotics%2C Automation%2C Sensing and Perception (GRASP) Lab":MAILTO:grasplab@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220413T120000
DTEND;TZID=America/New_York:20220413T130000
DTSTAMP:20260406T073451
CREATED:20220405T192052Z
LAST-MODIFIED:20220405T192052Z
UID:10007153-1649851200-1649854800@seasevents.nmsdev7.com
SUMMARY:Cell Mechanics Discussion Group
DESCRIPTION:
URL:https://seasevents.nmsdev7.com/event/cell-mechanics-discussion-group/
LOCATION:https://upenn.zoom.us/j/96715197752
ORGANIZER;CN="Center for Engineering MechanoBiology (CEMB)":MAILTO:annjeong@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220412T130000
DTEND;TZID=America/New_York:20220412T140000
DTSTAMP:20260406T073451
CREATED:20220331T213835Z
LAST-MODIFIED:20220331T213835Z
UID:10007144-1649768400-1649772000@seasevents.nmsdev7.com
SUMMARY:MEAM Ph.D. Thesis Defense: "Mechanical Properties of Fibrous Network Materials"
DESCRIPTION:We discuss mechanical behavior of specific fibrous network materials\, including the evolution of tension in fibrin clots\, compression of pulmonary emboli\, and fracture of Whatman filter paper. \nThe first material\, fibrin clots\, consist of random networks of fibrin fibers. When clots form by polymerization they develop tensile pre-stresses. We construct a mathematical model for the evolution of tension in isotropic fibrin gels. As the fiber diameter grows over time\, properties which depend on it\, such as the stored energy per unit length of a single fiber\, the force-stretch relation of a fiber\, and therefore the tension in the network as a whole\, also evolve over time. \nThe second fibrous network is pulmonary emboli\, which consist of random networks of fibrin fibers with fluid-filled pores and red blood cells (RBCs). Stress-strain responses of human pulmonary emboli under cyclic compression were measured\, revealing that emboli exhibit hysteretic stress-strain curves characteristic of foams. We describe the hysteretic response of emboli using a model of phase transitions\, in which the compressed embolus is segregated into coexisting rarefied and densified phases whose fractions change as compression progresses. Our model takes into account RBC rupture in compressed emboli and stresses due to fluid flow through their small pores. The mechanical response of emboli is shown to vary depending on their RBC content. \nThe third fibrous network is Whatman filter paper. The effect of humidity on properties such as out-of-plane fracture toughness of Whatman filter paper is studied for a broad range of relative humidities. Crack growth is modeled using traction-separation laws\, whose parameters are fitted to experiments. Additionally\, a novel model is developed to capture the high peak and sudden drop in the experimental force measurement caused by the existence of an initiation region\, an imperfect zone ahead of a nascent crack. The relative effect of each independent parameter is explored to better understand the humidity dependence of the traction-separation parameters.\nThe materials studied have biological\, clinical\, and industrial applications\, and the methods described here are also applicable to other fibrous network materials.
URL:https://seasevents.nmsdev7.com/event/meam-ph-d-thesis-defense-mechanical-properties-of-fibrous-network-materials/
LOCATION:Zoom – Email MEAM for Link\, peterlit@seas.upenn.edu
CATEGORIES:Dissertation or Thesis Defense
ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220412T103000
DTEND;TZID=America/New_York:20220412T113000
DTSTAMP:20260406T073451
CREATED:20220331T213440Z
LAST-MODIFIED:20220331T213440Z
UID:10007143-1649759400-1649763000@seasevents.nmsdev7.com
SUMMARY:MEAM Ph.D. Thesis Defense: "Metal and Air Generate Power for Robots"
DESCRIPTION:In many cases\, the size and weight of energy storage technologies required to power robotic systems are too large or massive for a robot to carry\, leading to limited operational times and long recharging times over which the robot remains unused. Computer-free autonomous decision making based on environmental cues provides exciting alternatives to classic control systems for robots and smart materials. Although this functionality has been studied in microswimmers and active colloids where energy in the surrounding liquid is prevalent\, there are no devices that can provide sufficient power from environmental chemicals to move and steer larger scale robots and vehicles in dry environments. \nIn this talk\, I will show a new approach for powering robots and electronics by electrochemically scavenging energy from metal surfaces. This approach overcomes energy storage scaling laws by allowing robots and electronics to extract energy from large volumes of energy dense material without having to carry the material on-board. Then\, we characterized the evolution of the metal during discharging by using FIB and Micro-CT in our system. Next\, we demonstrated an environmentally controlled voltage source that\, when directly attached to electric motors on a vehicle\, can increase the energy available to the vehicle and provide computer-free autonomous navigation toward chemical fuels in the environment and away from hazards. The voltage source uses electrochemistry to extract power from the chemical fuels\, and the vehicle avoids hazards that reduce the output voltage of electrochemical kinetics. \nThese works present a novel technique to simultaneously steer and power vehicles and robots without computers by directly responding to a wide variety of chemical fields in their environment using electrochemistry.
URL:https://seasevents.nmsdev7.com/event/meam-ph-d-thesis-defense-metal-and-air-generate-power-for-robots/
LOCATION:Zoom – Email MEAM for Link\, peterlit@seas.upenn.edu
CATEGORIES:Dissertation or Thesis Defense
ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220412T100000
DTEND;TZID=America/New_York:20220412T233000
DTSTAMP:20260406T073451
CREATED:20220329T181601Z
LAST-MODIFIED:20220329T181601Z
UID:10007137-1649757600-1649806200@seasevents.nmsdev7.com
SUMMARY:MEAM Seminar: "The Statistical Mechanics of Granular Clogging"
DESCRIPTION:The gravity-driven flow of grains from a hole in a hopper is an iconic granular phenomenon. It’s different from a fluid in that the rate is independent of fill height\, and more spectacularly so in that it can suddenly and unexpectedly clog. How does the susceptibility to clogging decrease with increasing hole size\, and is there a well-defined clogging transition above which the system never clogs? This problem is distinct from jamming due to the presence of boundaries and gradients. We show how the fraction F of flow configurations that cause a clog may be deduced from the average mass discharged between clogs. We construct a simple model to account for the observation that F decays exponentially in hole width to the power of dimensionality. Thus the clogging transition is not sharp but rather is defined by observation limits\, similar to the glass transition. When the system is immersed in water\, F barely changes. Therefore\, grain momenta play only a secondary role in destabilizing weak incipient arches and the crucial microscopic variables are likely the grain positions. Work is now in progress to distinguish free-flowing versus clog-causing position microstates using machine learning. Altogether\, this gives an entirely new way to think about clogging\, beyond the usual approach of investigating the zoology of possible arches and their mechanical stability.
URL:https://seasevents.nmsdev7.com/event/meam-seminar-the-statistical-mechanics-of-granular-clogging/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220412T100000
DTEND;TZID=America/New_York:20220412T120000
DTSTAMP:20260406T073451
CREATED:20220411T185012Z
LAST-MODIFIED:20220411T185012Z
UID:10007158-1649757600-1649764800@seasevents.nmsdev7.com
SUMMARY:CBE PhD Dissertation Defense | “The role of clot structure and mechanics on hemodynamics and pharmacology”
DESCRIPTION:Abstract: \n“Hemostatic clots have a core/shell hierarchy comprised of a P-selectin positive core surrounded by a P-selectin negative shell. A new human blood microfluidic assay utilizing a 2-stage assay was developed to interrogate core/shell mechanics. By first perfusing whole blood over a collagen/TF surface and then swapping out the blood for buffer\, we were able to pause thrombus growth at a specific point in time. The shear rate was then drastically increased to interrogate platelet-platelet interactions. We found that thrombin inhibition\, but not fibrin\, led to greater erosion of the thrombus\, and that the core region of the thrombus was stable with or without the presence of fibrin. Next\, we tested the effects of ADP or TxA2 inhibitors on thrombus growth and stability. We found that inhibiting TxA2 production did not affect platelet deposition\, but the platelets that did attach to the clot were more likely to shear off after being subjected to shear. Both P2Y1 and P2Y12 antagonism led to decreased initial platelet deposition and more platelet erosion. P2Y12 signaling had the most significant effect on deposition and stability suggesting that it might have an amplification effect on other signaling pathways. We demonstrated a new method to examine thrombus strength and stability and demonstrated the effect of thrombin on core size and the importance of secondary agonists on stability in the shell region.\nWe used an 8-channel microfluidic device to examine the efficacy of ex vivo apixaban on platelet and fibrin deposition in neonates with CHD. This patient population was shown to have significantly more activity blood after surgery We found that apixaban drastically lowers coagulation activity in neonatal blood before and after surgery and significantly prolongs occlusion time to a greater extent than adults. We also demonstrated that andexanet alfa reverses the inhibitory effect of apixaban in both neonates and adults. These results demonstrated that microfluidics are a useful way to examine pharmacological effects\, especially in a population where only small quantities of blood can be drawn.“
URL:https://seasevents.nmsdev7.com/event/cbe-phd-dissertation-defense-the-role-of-clot-structure-and-mechanics-on-hemodynamics-and-pharmacology/
LOCATION:Greenberg Lounge (Room 114)\, Skirkanich Hall\, 210 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Doctoral,Graduate,Student,Dissertation or Thesis Defense
ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220411T140000
DTEND;TZID=America/New_York:20220411T153000
DTSTAMP:20260406T073451
CREATED:20220404T143341Z
LAST-MODIFIED:20220404T143341Z
UID:10007149-1649685600-1649691000@seasevents.nmsdev7.com
SUMMARY:CBE PhD Dissertation Defense | "Understanding the relationship between clot contraction and platelet biology under hemodynamic conditions"
DESCRIPTION:Abstract: \n“As thrombosis proceeds\, platelets in a clot can expose phosphatidylserine (PS)\, providing a negatively charged surface for thrombin generation. These PS+ platelets have been shown to sort to the perimeter of platelet masses via platelet contraction. However\, it remains unclear how thrombin and fibrin affect PS+ platelet sorting within a clot. We used an 8-channel microfluidic device to perfuse blood over collagen/TF to evaluate temporal and spatial PS+ platelet sorting. We found that thrombin inhibition\, fibrin polymerization inhibition\, or fibrinolysis each increased clot contraction and PS sorting. Fibrin attenuated clot contraction and PS sorting. Clots without fibrin had a 3.6-times greater contraction than clots with fibrin. Based on these results\, we wanted to study contraction further. We tested the effect of inhibitors of ADP and/or thromboxane A2 (TXA2) signaling on clot contraction. We developed two automated imaging methods to score fluorescent platelet percent contraction: (1) “global” measurement of clot length\, and (2) “local” changes in surface area coverage of platelet aggregates within the clot. Total platelet FI and global aggregate contraction were highly correlated (R2 =0.87). Local aggregate contraction was more pronounced than global aggregate contraction across all inhibition conditions. Conditions with TXA2 inhibition were shown to significantly reduce local aggregate contraction relative to conditions without TXA2\, unlike conditions with ADP inhibition. Lastly\, we recently obtained a glycoprotein VI (GPVI) inhibitor. GPVI is a collagen receptor on platelets that drives platelet activation; however\, its role at later stages in clotting remains unclear. We tested the effect of anti-GPVI Fab on PS exposure\, which occurs at later stages of platelet activation. On collagen/TF\, Fab present at t=0s reduced PS exposure\, but had no effect when added 30 or 90 seconds later. Thrombin generated via PS exposure had an important role in driving platelet deposition when Fab was present\, since inhibition of PS via annexin V binding in the presence of Fab significantly inhibited platelet deposition. Our results from these studies help elucidate the relationship between platelet activation\, PS exposure\, fibrin\, and clot contraction.“
URL:https://seasevents.nmsdev7.com/event/cbe-phd-dissertation-defense-understanding-the-relationship-between-clot-contraction-and-platelet-biology-under-hemodynamic-conditions/
LOCATION:Greenberg Lounge (Room 114)\, Skirkanich Hall\, 210 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Doctoral,Graduate,Student,Dissertation or Thesis Defense
ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220411T120000
DTEND;TZID=America/New_York:20220411T130000
DTSTAMP:20260406T073451
CREATED:20220131T131755Z
LAST-MODIFIED:20220131T131755Z
UID:10007049-1649678400-1649682000@seasevents.nmsdev7.com
SUMMARY:PSOC@Penn Seminar: Morgan Huse\, PhD
DESCRIPTION:Physical Sciences in Oncology Center PSOC@Penn \nSpring 2022 Hybrid-Seminar Series \nTowne 225 / Raisler Lounge @ Noon (EST) \nFor Zoom link \, please contact manu@seas.upenn.edu
URL:https://seasevents.nmsdev7.com/event/psocpenn-seminar-morgan-huse-phd/
LOCATION:Raisler Lounge (Room 225)\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="PSOC":MAILTO:manu@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220411T093000
DTEND;TZID=America/New_York:20220411T103000
DTSTAMP:20260406T073451
CREATED:20220331T212512Z
LAST-MODIFIED:20220331T212512Z
UID:10007142-1649669400-1649673000@seasevents.nmsdev7.com
SUMMARY:MEAM Ph.D. Thesis Defense: "Relationships Between Structure\, Dynamics\, and Flow in Sheared Amorphous Materials"
DESCRIPTION:Amorphous solids\, those composed of haphazardly arranged constituents\, are found everywhere from our windows as silicate glass\, in the ground and foundations as mud and concrete\, and our grocery stores as granular piles of oranges. Even though they can be found over a huge range of length scales\, it remains a challenge to systematically design their mechanical properties using knowledge of their microstructure. In this thesis\, I investigate the link between the microstructure and the mechanical properties of a-thermal solids. \nFirst\, I probe the particle trajectories for chaotic signatures that relate to bulk rheology. Particles are confirmed to exhibit chaotic\, Brownian like motion during cyclic shear\, even though the particles are large enough that thermal motion is negligible. I also find that\, the average area traced by returning particles is proportional to the amplitude of strain\, which could be useful for \emph{in situ} measurements in industrial\, granular\, mixing applications. \nNext\, I examine the interconnection between particle dynamics and the arrangements of the constituents. I calculate the characteristic time for particles to shift past each other\, called relaxation time\, and the configurational entropy of the system in excess of a reference ideal gas. I show that the relaxation time at any given instant is related to the excess entropy a quarter shear cycle later\, which implies that the dynamics of particles shape the eventual structure. This means it is possible to take a snapshot of particle positions and infer its mechanical past. \nFinally\, I focus on the interplay between particle positions and bulk yield by using concepts from kinetics\, thermodynamics\, statistical mechanics\, and shear transformation zone theory. I establish a relationship between excess entropy and energy dissipation and uncover a novel definition for the yield transition based on memory signatures within the microstructure. Using these observations\, I derive a phenomenological model that links the microstructure to bulk rheology that is physically informed and whose parameters are all quantitatively measurable. This dissertation elucidates how the statistics of particle configurations and dynamics give rise to the macroscopic transition from elasticity to plasticity during yield of amorphous\, a-thermal solids.
URL:https://seasevents.nmsdev7.com/event/meam-ph-d-thesis-defense-relationships-between-structure-dynamics-and-flow-in-sheared-amorphous-materials/
LOCATION:Zoom – Email MEAM for Link\, peterlit@seas.upenn.edu
CATEGORIES:Dissertation or Thesis Defense
ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220408T140000
DTEND;TZID=America/New_York:20220408T150000
DTSTAMP:20260406T073451
CREATED:20220308T163523Z
LAST-MODIFIED:20220308T163523Z
UID:10007113-1649426400-1649430000@seasevents.nmsdev7.com
SUMMARY:PICS Colloquium "The Dynamics of Gas-Particle Partitioning: Insights from Laboratory\, Field\, and Modeling studies"
DESCRIPTION:Abstract: Ultrafine aerosols can significantly influence Earth’s climate if they are able to grow to sizes large enough to interact with the incoming solar radiation and nucleate cloud droplets. In clear air\, aerosol growth occurs via gas-to-particle conversion of condensable trace gases\, including sulfuric acid\, nitric acid\, hydrochloric acid\, ammonia\, and myriad oxidation products of many different volatile organic compounds. Nearly all aerosol models developed to date to simulate the aerosol growth assume instantaneous equilibrium between semivolatile gases and submicron-sized particles. This assumption effectively favors the growth of the largest pre-existing particles in accordance with Raoult’s law. In this talk\, I will use a combination of laboratory\, field\, and modeling studies to show that the equilibrium assumption may not always hold\, especially when aerosol growth occurs from condensation of supersaturated vapors and/or when the pre-existing aerosols are in a solid or semisolid phase state. In such cases\, gas-particle partitioning must be treated as a dynamic process and size-resolved bulk diffusion limitation must be considered inside semisolid particles. I will outline a computationally efficient dynamic gas-particle partitioning treatment in the MOSAIC aerosol model to address this issue and discuss implications on the growth of ultrafine aerosols from semivolatile vapors.
URL:https://seasevents.nmsdev7.com/event/pics-colloquium-the-dynamics-of-gas-particle-partitioning-insights-from-laboratory-field-and-modeling-studies/
LOCATION:Zoom – email kathom@seas.upenn.edu
CATEGORIES:Colloquium
ORGANIZER;CN="Penn Institute for Computational Science (PICS)":MAILTO:dkparks@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220408T110000
DTEND;TZID=America/New_York:20220408T120000
DTSTAMP:20260406T073451
CREATED:20220404T123530Z
LAST-MODIFIED:20220404T123530Z
UID:10007148-1649415600-1649419200@seasevents.nmsdev7.com
SUMMARY:ESE Spring Seminar - "End-to-end Learning for Robust Decision Making"
DESCRIPTION:Because the physical world is complex\, ambiguous\, and unpredictable\, autonomous agents must be engineered to exhibit a human-level degree of flexibility and generality — far beyond what we are capable of explicitly programming. Achieving such rich and intricate decision making requires rethinking the foundations of intelligence across all stages of the autonomous learning lifecycle. \nIn this talk\, I will share new learning-based approaches towards dynamic\, resilient\, and robust decision making of autonomous systems. Such solutions are capable of not only reliably solving a particular problem\, but also anticipating what could go wrong in order to strategize\, adapt\, and continuously learn. We advance robust decision making by (1) computationally designing rich synthetic environments of hard to collect\, out-of-distribution edge-cases; (2) creating efficient\, expressive\, and interpretable learning models; and (3) developing adaptive\, robust\, and grounded learning algorithms\, and exploiting their interdependence to realize generalizable decision making.
URL:https://seasevents.nmsdev7.com/event/ese-spring-seminar-end-to-end-learning-for-robust-decision-making/
LOCATION:Heilmeier Hall (Room 100)\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar,Colloquium
ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220408T103000
DTEND;TZID=America/New_York:20220408T114500
DTSTAMP:20260406T073451
CREATED:20220113T180556Z
LAST-MODIFIED:20220113T180556Z
UID:10007012-1649413800-1649418300@seasevents.nmsdev7.com
SUMMARY:GRASP on Robotics: Jing Xiao\, Worcester Polytechnic Institute\, “Perception-Action Synergy in Uncertain Environments”
DESCRIPTION:Many robotic applications require a robot to operate in an environment with unknowns or uncertainty\, at least initially\, before it gathers enough information about the environment. In such a case\, a robot must rely on sensing and perception to feel its way around. Moreover\, it has to couple sensing/perception and motion synergistically in real time\, such that perception guides motion\, while motion enables better perception. In this talk\, I will introduce our research in combining perception and motion of a robot to achieve autonomous contact-rich assembly\, object recognition\, object modeling\, and constrained manipulation in uncertain or unknown environments\, under force/torque\, RGBD\, or touch sensing. I will also introduce our recent work on integrated semantic SLAM and accurate loop closure detection\, SmSLAM+LCD.
URL:https://seasevents.nmsdev7.com/event/grasp-on-robotics-perception-action-synergy-in-uncertain-environments/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="General Robotics%2C Automation%2C Sensing and Perception (GRASP) Lab":MAILTO:grasplab@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220407T153000
DTEND;TZID=America/New_York:20220407T163000
DTSTAMP:20260406T073451
CREATED:20220329T212252Z
LAST-MODIFIED:20220329T212252Z
UID:10007139-1649345400-1649349000@seasevents.nmsdev7.com
SUMMARY:MEAM Ph.D. Thesis Defense: "User-friendly\, Low-cost\, Microfluidic Devices with Capillary Circuits for Multiplexed\, Isothermal\, Point-of-care Nucleic Acid Amplification Tests"
DESCRIPTION:Rapid\, sensitive\, and specific detection of causative pathogens is key to personalized medicine and the prompt implementation of appropriate mitigation measures to reduce disease transmission\, mortality\, morbidity\, and cost. Conventional molecular detection methods require trained personnel\, sophisticated equipment\, and specialized laboratories\, which limits their use to centralized laboratories. To enable molecular diagnostics at the point of need and in resource-poor settings\, inexpensive\, simple devices that combine multiple unit operations and are capable of co-detecting endemic pathogens are needed. \nIn this dissertation\, I have developed microfluidic devices with capillary circuits to automate liquid distribution\, eliminating the need for expensive equipment\, sophisticated laboratory facilities\, and skilled personnel to enable molecular diagnostics at the point of need. Capillary valves with different sizes were developed and implemented to aliquot samples and reagents to multiple reaction chambers and to enable draining liquids from supply lines without affecting liquids in the various reaction chambers\, enabling bubble-free operation. The sealing of my microfluidic devices to prevent evaporation during incubation is facilitated with phase-change materials and capillary-induced motion. When my microfluidic chip is heated to its incubation temperature\, the phase change material melts and flows to seal ports of entry and air vent. Numerical simulations were carried out to assess the viability of on-chip\, in-house developed\, two-stage isothermal nucleic acid amplification in the presence of diffusion and advection. An Android-based smartphone application was developed to automate real-time signal monitoring\, time series image analysis\, and diagnostic result interpretation. Three different 3D-printed\, portable\, microfluidic devices with capillary circuits were designed\, fabricated\, and tested for single-stage and two-stage\, isothermal nucleic acid amplification with either liquid reagents or ii pre-stored dry reagents that do not require a cold chain. All devices have proved successful for rapid\, sensitive\, and specific multiplexed detections of human and animal pathogens.
URL:https://seasevents.nmsdev7.com/event/meam-ph-d-thesis-defense-user-friendly-low-cost-microfluidic-devices-with-capillary-circuits-for-multiplexed-isothermal-point-of-care-nucleic-acid-amplification-tests/
LOCATION:Zoom – Email MEAM for Link\, peterlit@seas.upenn.edu
CATEGORIES:Dissertation or Thesis Defense
ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220407T153000
DTEND;TZID=America/New_York:20220407T163000
DTSTAMP:20260406T073451
CREATED:20211210T164738Z
LAST-MODIFIED:20211210T164738Z
UID:10006995-1649345400-1649349000@seasevents.nmsdev7.com
SUMMARY:BE Seminar: "Analysis of High-content Genomic Screening Data with Large-scale Optical Pooled Screens" (Paul Blainey\, MIT)
DESCRIPTION:This seminar will be held in person in Towne 337 and on zoom (check email for link or contact ksas@seas.upenn.edu). \nGenetic screens are critical for the systematic identification of genes underlying cellular phenotypes. While pooling gene perturbations greatly increases screening throughput\, this approach was not yet compatible with the high-content imaging of complex and dynamic cellular phenotypes. Our group recently developed optical pooled screening using in situ sequencing-by-synthesis to link pooled perturbations with their associated visual phenotypic outcomes at the single-cell level in mammalian cells. We have since established this approach for very large-scale screens where hundreds of phenotypic parameters are recorded for each cell.  I will provide an overview of the applicability of this kind of approach and discuss in more detail two large-scale\, high-content collaborative screening projects\, one related to intracellular responses to viral infection\, and another focused on human cell division phenotypes.
URL:https://seasevents.nmsdev7.com/event/be-seminar-paul-blainey/
LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="Bioengineering":MAILTO:be@seas.upenn.edu
END:VEVENT
END:VCALENDAR