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DTSTART;TZID=America/New_York:20200504T140000
DTEND;TZID=America/New_York:20200504T153000
DTSTAMP:20260407T192143
CREATED:20200429T184222Z
LAST-MODIFIED:20200429T184222Z
UID:10006431-1588600800-1588606200@seasevents.nmsdev7.com
SUMMARY:Virtual Joint Seminar: Open Source Multicellular Systems Modeling for Cancer (and COVID-19)
DESCRIPTION:Virtual Joint Seminar of Penn PSOC\, Bioengineering\, PICS \nFor Zoom details\, email gormley@seas.upenn.edu \nCancer and other critical human health problems are inherently multiscale: molecular-scale processes such as receptor trafficking and metabolism drive cell-scale processes such as cycling and motility. Biophysical processes like diffusion and tissue mechanics both constrain and drive single-cell behavior. Moreover\, cells communicate and coordinate through chemical and mechanical processes. All these processes are dynamically linked to drive emergent multicellular systems behaviors in healthy and diseased tissues. \nComputational models can act as “virtual laboratories” for multicellular systems biology. The ideal such laboratory should include cell and tissue biomechanics\, biotransport of multiple chemical substrates including signaling factors\, and many interacting cells. This talk presents PhysiCell (http://dx.doi.org/10.1371/journal.pcbi.1005991)\, an open source agent-based platform for 3-D multicellular systems biology. With PhysiCell\, desktop workstations can routinely simulate systems of ten or more cell-secreted chemical signals and tissue substrates\, along with 10^5 to 10^6 individual cells that grow\, divide\, die\, secrete chemical signals\, move\, exchange mechanical forces\, and remodel their tissue microenvironment. High-performance computing (HPC) resources can run tens of thousands of copies of these models to perform vast 3-D computational experiments\, and artificial intelligence (AI) techniques can help us to accelerate these investigations and analyze the simulation results. \nWe will explore PhysiCell models of two cancer problems: (1) We will investigate how tumor-parenchyma biomechanical cross-talk can lead to tumor dormancy in liver micrometastases\, and how changes in tissue mechanics (e.g.\, after an illness\, injury\, or aging) can lead to tumor “reawakening”. (2) We will explore the critical role of stochastic tumor-immune interactions in cancer immunosurveillance. We will show joint work with Argonne National Lab to explore large hypothesis and design spaces on supercomputers\, as well as very recent advances in using machine learning to accelerate these explorations while also improving model interpretation. \nWe will also present work by a growing coalition of mathematicians\, virologists\, immunologists\, pharmacologists\, and others to rapidly prototype and iteratively improve a comprehensive multiscale SARS-CoV-2 tissue simulator. The first prototype model was built and shared internationally as open source code and interactive\, cloud-hosted models in under 12 hours\, and the work was disseminated as a community-written preprint within a week. The second prototype was updated to include ACE2 receptor-driven virus endocytosis and a more modular design; the third prototype is well underway. This coalition-based approach is developing submodel components in parallel and coordination\, allowing us to rapidly advance towards a feature complete framework to drive many independent investigations that help us attack COVID-19. This project shows the potential for similar community-driven advances in cancer. Moreover\, the novel mix of cancer biologists\, immunologists\, microbiologists\, and others is fueling creative advances and new technical capabilities in multiscale tissue modeling. We anticipate that this progress will drive advances in cancer immunology\, inflammation\, and virus-driven carcinogenesis for years to come. \nPhysiCell Animation \nhttps://www.youtube.com/watch?v=nJ2urSm4ilU&authuser=0
URL:https://seasevents.nmsdev7.com/event/virtual-joint-seminar-open-source-multicellular-systems-modeling-for-cancer-and-covid-19/
CATEGORIES:Seminar
ORGANIZER;CN="Bioengineering":MAILTO:be@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200504T120000
DTEND;TZID=America/New_York:20200504T130000
DTSTAMP:20260407T192143
CREATED:20200109T174742Z
LAST-MODIFIED:20200109T174742Z
UID:10006377-1588593600-1588597200@seasevents.nmsdev7.com
SUMMARY:PSOC Seminar Cancelled : “A physics-driven open source software ecosystem for multicellular systems biology”
DESCRIPTION:
URL:https://seasevents.nmsdev7.com/event/psoc-seminar-a-physics-driven-open-source-software-ecosystem-for-multicellular-systems-biology/
LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
ORGANIZER;CN="PSOC":MAILTO:manu@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200424T100000
DTEND;TZID=America/New_York:20200424T120000
DTSTAMP:20260407T192143
CREATED:20200414T154312Z
LAST-MODIFIED:20200414T154312Z
UID:10006430-1587722400-1587729600@seasevents.nmsdev7.com
SUMMARY:CBE Dissertation Defense: "Strategies for Overcoming Resistance to Targeted Therapy in Glioblastoma"
DESCRIPTION:Co-Advisors: Matthew J. Lazzara\, PhD and Dennis E. Discher\, PhD; Committee Members: Scott L. Diamond\, PhD\, M. Celeste Simon\, PhD and Benjamin Purow
URL:https://seasevents.nmsdev7.com/event/cbe-dissertation-defense-strategies-for-overcoming-resistance-to-targeted-therapy-in-glioblastoma/
LOCATION:Zoom – Email CIS for link\, cherylh@cis.upenn.edu
ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200423T150000
DTEND;TZID=America/New_York:20200423T160000
DTSTAMP:20260407T192143
CREATED:20200303T175720Z
LAST-MODIFIED:20200303T175720Z
UID:10006424-1587654000-1587657600@seasevents.nmsdev7.com
SUMMARY:Closing the Gap between Theory and Practice: Rethinking Engineering Education in Real Time
DESCRIPTION:Despite 20 years of focus on organizational change and effective educational best practices in STEM higher education\, significant research findings have had minimal influences on practice.  In 2016\, the U-M BME Department sought to disrupt engineering education. Informed by organizational change theory\, we asked: 1) Is there potential for change; 2) what strategies facilitate change; and 3) how can these strategies be implemented? As a result\, we developed an Instructional Design Sequence\, a new approach to instruction in which students\, post docs\, and faculty create short Modules that use evidence-based teaching practices to expose BME students to BME professional practice.  This talk describes how the Sequence was conceived of and demonstrates how organizational theory\, entrepreneurship\, and design can be used to inform education practice. The resultant Sequence has the potential to be a transferrable model for transforming engineering education\, offering a new mechanism for integrating career relevant curriculum into undergraduate curriculum in real-time\, while training future educators in instructional evidence based practices. \n  \nThis lecture is offered as part of the Lecturers’ Seminar on Teaching and Learning.
URL:https://seasevents.nmsdev7.com/event/closing-the-gap-between-theory-and-practice-rethinking-engineering-education-in-real-time/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200422T150000
DTEND;TZID=America/New_York:20200422T160000
DTSTAMP:20260407T192143
CREATED:20191219T211511Z
LAST-MODIFIED:20191219T211511Z
UID:10006357-1587567600-1587571200@seasevents.nmsdev7.com
SUMMARY:Cancelled: CBE Seminar - Biomaterials-Mediated Inflammation Control"
DESCRIPTION:Abstract: \nMany chronic disabling diseases such as rheumatoid arthritis\, psoriasis\, multiple sclerosis and systemic lupus erythematosus are increasingly linked to inappropriate and chronic activation of inflammatory cells. A central event in the pathogenesis of these diseases appears to be an aberrant activation of innate immune sensors\, most prominently the Pattern Recognition Receptors (PRRs)\, by nucleic acids that are released from dead and dying cells. Moreover\, such extracellular nucleic acids have also been implicated in inflammatory diseases such as heart attack\, traumatic injury\, and stroke in activating the contact pathway of coagulation. In this presentation\, I will discuss the application of nucleic acid-binding polymers in the configuration of either soluble or immobilized polycation to scavenge these pathogenic nucleic acids as a molecular strategy to combat inflammation.
URL:https://seasevents.nmsdev7.com/event/cbe-seminar-biomaterials-mediated-inflammation-control/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200420T150000
DTEND;TZID=America/New_York:20200420T170000
DTSTAMP:20260407T192143
CREATED:20200407T210029Z
LAST-MODIFIED:20200407T210029Z
UID:10006428-1587394800-1587402000@seasevents.nmsdev7.com
SUMMARY:CBE Dissertation Defense: "Role of Soluble Fibrin and Fibrin Degradation Products on Platelet Signaling During Trauma
DESCRIPTION:Advisor: Scott Diamond\, PhD; Committee Members: Talid Sinno\, PhD; Ravi Radhakrishnan\, PhD; Lawrence Brass\, PhD
URL:https://seasevents.nmsdev7.com/event/cbe-dissertation-defense-role-of-soluble-fibrin-and-fibrin-degradation-products-on-platelet-signaling-during-trauma/
LOCATION:Zoom – Email CIS for link\, cherylh@cis.upenn.edu
CATEGORIES:Dissertation or Thesis Defense
ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200420T120000
DTEND;TZID=America/New_York:20200420T130000
DTSTAMP:20260407T192143
CREATED:20200109T174423Z
LAST-MODIFIED:20200109T174423Z
UID:10006376-1587384000-1587387600@seasevents.nmsdev7.com
SUMMARY:PSOC Seminar Cancelled : Patrick Seale\, PhD
DESCRIPTION:
URL:https://seasevents.nmsdev7.com/event/psoc-seminar-patrick-seale-phd/
LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
ORGANIZER;CN="PSOC":MAILTO:manu@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200415T150000
DTEND;TZID=America/New_York:20200415T170000
DTSTAMP:20260407T192143
CREATED:20200408T125947Z
LAST-MODIFIED:20200408T125947Z
UID:10006429-1586962800-1586970000@seasevents.nmsdev7.com
SUMMARY:BE Thesis Defense: "Development and application of computational tools for unraveling the structure of the 3D genome"
DESCRIPTION:Thomas Gilgenast’s thesis defense \nDate and Time: Wednesday 4/15\, 3:00pm EST \nTitle: Development and application of computational tools for unraveling\nthe structure of the 3D genome \nAdvisor: Dr. Jennifer Cremins \nThomas’ defense will take place virtually via Zoom. Please contact\njcremins@seas.upenn.edu for the zoom link and password.
URL:https://seasevents.nmsdev7.com/event/be-thesis-defense-development-and-application-of-computational-tools-for-unraveling-the-structure-of-the-3d-genome/
CATEGORIES:Student,Dissertation or Thesis Defense
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200414T103000
DTEND;TZID=America/New_York:20200414T120000
DTSTAMP:20260407T192143
CREATED:20200305T150550Z
LAST-MODIFIED:20200305T150550Z
UID:10006426-1586860200-1586865600@seasevents.nmsdev7.com
SUMMARY:CANCELLED: MEAM Seminar: "Modeling the Behavior of Shape Memory Alloy Structures"
DESCRIPTION:I will present recent work on the modeling of the structural response of shape memory alloy tubes\, bars\, and beams. We have developed a new constitutive model that captures pseudoelastic transformation induced recoverable deformation in SMAs including the strong asymmetries in the tensile and compressive responses. Instead of introducing multiple conditions for forward phase transformation\, reverse phase transformation\, and martensite reorientation\, the model is based on a J2-type nonlinear kinematic hardening framework with a single transformation surface and the back stress represented through a weighted mix of two potential functions that are calibrated to the tensile and compressive stress-strain responses of the material. The constitutive model has been used to simulate numerically the interaction of these complex material behaviors with structural nonlinear behavior observed in experiments. Problems analyzed include the buckling and recovery of NiTi tubes under axial compression\, the propagation of a well defined deformation front in uniaxial tension\, and the reversible propagation of curvature localization in NiTi tubes under bending. The numerical simulations reproduce the structural behavior both qualitatively and quantitatively demonstrating the fidelity of the constitutive modeling framework developed. After illustrating the success of the isothermal model\, I will present some recent work on modeling non-isothermal behavior within the same constitutive framework.
URL:https://seasevents.nmsdev7.com/event/meam-seminar-modeling-the-behavior-of-shape-memory-alloy-structures/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200413T120000
DTEND;TZID=America/New_York:20200413T130000
DTSTAMP:20260407T192143
CREATED:20200109T174123Z
LAST-MODIFIED:20200109T174123Z
UID:10006375-1586779200-1586782800@seasevents.nmsdev7.com
SUMMARY:PSOC Seminar Cancelled : Alexandra Zidovska\, PhD
DESCRIPTION:
URL:https://seasevents.nmsdev7.com/event/psoc-seminar-alexandra-zidovska-phd/
LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
ORGANIZER;CN="PSOC":MAILTO:manu@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200408T150000
DTEND;TZID=America/New_York:20200408T160000
DTSTAMP:20260407T192143
CREATED:20191219T205845Z
LAST-MODIFIED:20191219T205845Z
UID:10006356-1586358000-1586361600@seasevents.nmsdev7.com
SUMMARY:POSTPONED: John A. Quinn Distinguished Lecture: "Molecular and Colloidal Interactions in Water"
DESCRIPTION:Abstract: \nLife occurs in water\, and water-mediated interactions between molecules and interfaces are central to biological assembly processes.  Synthetic materials as common as shampoo rely on water-mediated interactions.  This presentation will describe experiments that highlight our lack of understanding of interactions in water. This lack of understanding presents the opportunity to formulate a refined set of design rules for self-assembly of engineered functional materials in water.
URL:https://seasevents.nmsdev7.com/event/john-a-quinn-distinguished-lecture-molecular-and-colloidal-interactions-in-water/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar,Distinguished Lecture
ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200407T103000
DTEND;TZID=America/New_York:20200407T120000
DTSTAMP:20260407T192143
CREATED:20200303T185112Z
LAST-MODIFIED:20200303T185112Z
UID:10006425-1586255400-1586260800@seasevents.nmsdev7.com
SUMMARY:CANCELLED: MEAM Seminar: "U.S. Army Additive Manufacturing Materials and Technologies"
DESCRIPTION:With the constantly changing threat environment\, the Army needs to be able to quickly adapt their tactics and equipment. But burdensome and lengthy acquisition cycles make this challenging. Additive manufacturing can potentially be utilized to overcome many of the challenges and enables on-demand manufacturing of repair parts\, as well as rapid prototyping.\nThrough topology optimization\, parts can be designed lighter and/or stronger and more cost-effective. In addition to new technologies being explored such as hybrid manufacturing in which entire metal and plastic devices can be fabricated within the same piece of equipment\, a host of novel feedstocks are being developed such as multi-material thermoplastics and filled resins that further increase the range of properties and applications of the 3D printed parts. In addition to the research performed in Army laboratories\, one of the major thrusts of current Army additive manufacturing research is the ability to manufacture at the point of need in remote environments. Research at the US Army Research Laboratory Combat Capabilities Development Command (CCDC-ARL) is showing that agile\, expeditionary manufacturing could be accomplished through the use of materials at or near to the location of our operating bases. These materials could include not only commercial feedstocks\, but also the organic and inorganic materials naturally occurring in the area and recycled materials from the operating bases such as polymers\, metals\, and paper materials. Distributed manufacturing could reduce the logistics tail needed to conduct wars on foreign soil\, saving valuable resources and lives\, and allowing the warfighter to perform the mission\, instead of guarding and securing convoy transports. In addition to reduced energy costs related to transportation\, the operational readiness and self-sustainability of operating bases would be increased.
URL:https://seasevents.nmsdev7.com/event/meam-seminar-u-s-army-additive-manufacturing-materials-and-technologies/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200406T120000
DTEND;TZID=America/New_York:20200406T130000
DTSTAMP:20260407T192143
CREATED:20200109T173727Z
LAST-MODIFIED:20200109T173727Z
UID:10006374-1586174400-1586178000@seasevents.nmsdev7.com
SUMMARY:PSOC Seminar Cancelled :”Interplay of receptor tyrosine kinase activation at the cell surface and environmental mechanics”
DESCRIPTION:
URL:https://seasevents.nmsdev7.com/event/psoc-seminar-interplay-of-receptor-tyrosine-kinase-activation-at-the-cell-surface-and-environmental-mechanics/
LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
ORGANIZER;CN="PSOC":MAILTO:manu@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200403T153000
DTEND;TZID=America/New_York:20200403T170000
DTSTAMP:20260407T192143
CREATED:20200124T165903Z
LAST-MODIFIED:20200124T165903Z
UID:10006389-1585927800-1585933200@seasevents.nmsdev7.com
SUMMARY:ESE Ph.D. Thesis Defense
DESCRIPTION:ESE
URL:https://seasevents.nmsdev7.com/event/ese-ph-d-thesis-defense/
LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Dissertation or Thesis Defense
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200403T140000
DTEND;TZID=America/New_York:20200403T150000
DTSTAMP:20260407T192143
CREATED:20200114T165030Z
LAST-MODIFIED:20200114T165030Z
UID:10006381-1585922400-1585926000@seasevents.nmsdev7.com
SUMMARY:Cancelled: PICS Seminar - Dr. Francesco Paesani of the University of California\, San Diego\, Department of Chemistry and Biochemistry
DESCRIPTION:
URL:https://seasevents.nmsdev7.com/event/pics-seminar-with-dr-francesco-paesani-of-the-university-of-california-san-diego-department-of-chemistry-and-biochemistry/
LOCATION:PICS Conference Room 534 – A Wing \, 5th Floor\, 3401 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar,Colloquium
ORGANIZER;CN="Penn Institute for Computational Science (PICS)":MAILTO:dkparks@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200401T150000
DTEND;TZID=America/New_York:20200401T160000
DTSTAMP:20260407T192143
CREATED:20191219T205002Z
LAST-MODIFIED:20191219T205002Z
UID:10006355-1585753200-1585756800@seasevents.nmsdev7.com
SUMMARY:CANCELLED: CBE Seminar - "Model-Based Chemical Product Design and Analysis"
DESCRIPTION:Abstract: \nChemical products are usually designed and developed through heuristic rule-based and/or trial-and-error experiment-based approaches. Although this kind of approaches often lead to safe and reliable product designs\, since it is not practically feasible to consider all alternatives\, it may not be possible to find the optimal product. As an alternative approach\, the use of model-based design methods has been gaining increased attention as they have the potential to rapidly generate and/or screen product candidates in a much larger design space\, and therefore reduce cost for chemical product design and development. If needed data and/or models giving reliable estimations for product properties and functions are available\, model-based chemical product design methods may be applied for design and analysis of many chemical products classified as single species (such as refrigerants\, solvents\, and chemical substitutes) and multiple species (such as fuel blends\, insect repellents\, detergents and paint formulations). The seminar will highlight\, with special emphasis on predictive chemical product property modelling\, a model-based computer-aided framework plus associated methods and software tools for systematic design and analysis of a wide range of chemical products.
URL:https://seasevents.nmsdev7.com/event/cbe-seminar-model-based-chemical-product-design-and-analysis/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200331T103000
DTEND;TZID=America/New_York:20200331T120000
DTSTAMP:20260407T192143
CREATED:20200109T164226Z
LAST-MODIFIED:20200109T164226Z
UID:10006365-1585650600-1585656000@seasevents.nmsdev7.com
SUMMARY:CANCELLED: MEAM Seminar: "Tackling Energy Sector Challenges with Interdisciplinary Research and Education Initiatives"
DESCRIPTION:Tackling the energy sector’s pressing technological and workforce needs requires a multi-pronged approach. This talk will include a discussion of both technical research and educational approaches to address these needs. The educational initiatives include implementation of the Energy Fellows Program\, a training and professional development program\, as well as research on the varying perceptions of students\, faculty\, and practicing engineers about what skills and knowledge are required for careers in the energy sector. The technical research focuses on conversion of waste heat into electricity since the majority of energy resources are wasted as heat. Thermoelectric power generators can convert waste heat into useful electrical energy\, but traditional thermoelectric device manufacturing uses bulk material processing with machining\, assembly\, and integration steps which lead to material waste and performance limitations. The traditional manufacturing approach offers virtually no flexibility in designing the geometry of thermoelectric modules. Additive manufacturing can overcome these challenges. This presentation will describe our progress in laser-based additive manufacturing of thermoelectric materials such as tellurides and silicides. Laser powder bed fusion (also known as selective laser melting) is an additive manufacturing process which locally melts successive layers of material powder to construct three-dimensional objects. When applied to thermoelectric materials\, this technique could enable new geometries and architectures\, material-to-device integration\, and large-area processing. The presentation will show the first demonstrations of laser additive manufacturing applied to thermoelectric materials and discuss the link between materials\, manufacturing\, and system-level considerations for thermoelectric power generators.
URL:https://seasevents.nmsdev7.com/event/meam-seminar-tackling-energy-sector-challenges-with-interdisciplinary-research-and-education-initiatives/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200330T120000
DTEND;TZID=America/New_York:20200330T130000
DTSTAMP:20260407T192143
CREATED:20200109T173301Z
LAST-MODIFIED:20200109T173301Z
UID:10006373-1585569600-1585573200@seasevents.nmsdev7.com
SUMMARY:PSOC Seminar Cancelled : “Chromatin dynamics and DNA repair”
DESCRIPTION:
URL:https://seasevents.nmsdev7.com/event/psoc-seminar-chromatin-dynamics-and-dna-repair/
LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
ORGANIZER;CN="PSOC":MAILTO:manu@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200325T133000
DTEND;TZID=America/New_York:20200325T143000
DTSTAMP:20260407T192143
CREATED:20200221T170859Z
LAST-MODIFIED:20200221T170859Z
UID:10006417-1585143000-1585146600@seasevents.nmsdev7.com
SUMMARY:Cancelled CIS Seminar:" Harnessing the Power of People: Human-AI Interaction Design in Healthcare\, Language\, and Beyond"
DESCRIPTION:Abstract: \nSome claim AI is the “new electricity” due to its growing significance and ubiquity. My research investigates this vision from an HCI perspective: How can we situate this remarkable technology in ways people perceive as valuable? How could we form a symbiotic relationship between AI systems and their users\, to do things neither can do on their own? \nIn this talk\, I will discuss a number of research projects that systematically investigate these questions. Projects include the designs of clinical decision-support systems that can effectively collaborate with doctors in making life-and-death decisions and an investigation of how Natural Language Generation systems might seamlessly serve authors’ communicative intent. Each project engages stakeholders in their real-world contexts and addresses a critical challenge in transitioning AI from the research lab to the real world. \nBased upon this body of work and my studies of industry practice\, I propose a framework laying out the problem space of human-AI interaction design. I discuss our early work and the strategic potential in supporting effective collaboration between HCI and AI expertise.
URL:https://seasevents.nmsdev7.com/event/cis-seminar-harnessing-the-power-of-people-human-ai-interaction-design-in-healthcare-language-and-beyond-2/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Colloquium
ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200325T133000
DTEND;TZID=America/New_York:20200325T143000
DTSTAMP:20260407T192143
CREATED:20200220T194614Z
LAST-MODIFIED:20200220T194614Z
UID:10006416-1585143000-1585146600@seasevents.nmsdev7.com
SUMMARY:Cancelled: CIS Seminar: "Harnessing the Power of People: Human-AI Interaction Design in Healthcare\, Language\, and Beyond"
DESCRIPTION:Abstract: \nSome claim AI is the “new electricity” due to its growing significance and ubiquity. My research investigates this vision from an HCI perspective: How can we situate this remarkable technology in ways people perceive as valuable? How could we form a symbiotic relationship between AI systems and their users\, to do things neither can do on their own? \nIn this talk\, I will discuss a number of research projects that systematically investigate these questions. Projects include the designs of clinical decision-support systems that can effectively collaborate with doctors in making life-and-death decisions and an investigation of how Natural Language Generation systems might seamlessly serve authors’ communicative intent. Each project engages stakeholders in their real-world contexts and addresses a critical challenge in transitioning AI from the research lab to the real world. \nBased upon this body of work and my studies of industry practice\, I propose a framework laying out the problem space of human-AI interaction design. I discuss our early work and the strategic potential in supporting effective collaboration between HCI and AI expertise.
URL:https://seasevents.nmsdev7.com/event/cis-seminar-harnessing-the-power-of-people-human-ai-interaction-design-in-healthcare-language-and-beyond/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Colloquium
ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200325T120000
DTEND;TZID=America/New_York:20200325T133000
DTSTAMP:20260407T192143
CREATED:20200226T145428Z
LAST-MODIFIED:20200226T145428Z
UID:10006421-1585137600-1585143000@seasevents.nmsdev7.com
SUMMARY:CANCELLED: Sustaining Women's Progress in STEM: Students\, Staff & Faculty Share Voices
DESCRIPTION:  \n\n\n\nUnfortunately\, due to protocols surrounding the coronavirus (COVID-19)\, this event has been cancelled. We hope to see it rescheduled for the fall. Please contact Rashmi Kumar (rashmik@upenn.edu) with any questions. \n 
URL:https://seasevents.nmsdev7.com/event/sustaining-womens-progress-in-stem-students-staff-faculty-share-voices/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200324T150000
DTEND;TZID=America/New_York:20200324T160000
DTSTAMP:20260407T192143
CREATED:20200221T171126Z
LAST-MODIFIED:20200221T171126Z
UID:10006418-1585062000-1585065600@seasevents.nmsdev7.com
SUMMARY:Cancelled: CIS Seminar:"New Compilation Techniques for Reconfigurable Analog Devices"
DESCRIPTION:Abstract:\n\n\nReconfigurable analog devices are a powerful new computing substrate especially appropriate for executing dynamical systems in an energy efficient manner. These devices leverage the physical behavior of transistors to directly implement computation. Under this paradigm\, voltages and currents within the device implement continuously evolving variables in the computation.\n\nIn this talk\, I discuss compilation techniques for automatically configuring such devices to execute dynamical systems. I present Legno\, the first compilation system that automatically targets a real reconfigurable analog device of this class. Legno synthesizes analog circuits from parametric and specialized analog blocks and accounts for analog noise\, quantization error\, operating range limitations\, and manufacturing variations within the device. I evaluate Legno on applications from the biology\, physics\, and controls domains. The results demonstrate that these applications execute with acceptable error while consuming microjoules of energy.
URL:https://seasevents.nmsdev7.com/event/cis-seminarnew-compilation-techniques-for-reconfigurable-analog-devices/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Colloquium
ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200323T120000
DTEND;TZID=America/New_York:20200323T130000
DTSTAMP:20260407T192143
CREATED:20200109T172740Z
LAST-MODIFIED:20200109T172740Z
UID:10006371-1584964800-1584968400@seasevents.nmsdev7.com
SUMMARY:PSOC Seminar Cancelled: 'Visualizing Cancer Biology: From Single molecules to Systems'
DESCRIPTION:
URL:https://seasevents.nmsdev7.com/event/psoc-seminar-visualizing-cancer-biology-from-single-molecules-to-systems/
LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
ORGANIZER;CN="PSOC":MAILTO:manu@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200320T140000
DTEND;TZID=America/New_York:20200320T150000
DTSTAMP:20260407T192143
CREATED:20191118T172045Z
LAST-MODIFIED:20191118T172045Z
UID:10006338-1584712800-1584716400@seasevents.nmsdev7.com
SUMMARY:Cancelled: PICS Seminar - Dr. Ivan Bermejo-Moreno of the University of Southern California\, Viterbi School of Engineering
DESCRIPTION:
URL:https://seasevents.nmsdev7.com/event/pics-seminar-with-dr-ivan-bermejo-moreno-of-usc-viterbi-school-of-engineering/
LOCATION:PICS Conference Room 534 – A Wing \, 5th Floor\, 3401 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Colloquium
ORGANIZER;CN="Penn Institute for Computational Science (PICS)":MAILTO:dkparks@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200319T150000
DTEND;TZID=America/New_York:20200319T160000
DTSTAMP:20260407T192143
CREATED:20200220T192914Z
LAST-MODIFIED:20200220T192914Z
UID:10006415-1584630000-1584633600@seasevents.nmsdev7.com
SUMMARY:Cancelled: CIS Seminar: "Deep Probabilistic Graphical Modeling"
DESCRIPTION:Abstract: \nDeep learning (DL) is a powerful approach to modeling complex and large scale data. However\, DL models lack interpretable quantities and calibrated uncertainty. In contrast\, probabilistic graphical modeling (PGM) provides a framework for formulating an interpretable generative process of data and a way to express uncertainty about what we do not know. How can we develop machine learning methods that bring together the expressivity of DL with the interpretability and calibration of PGM to build flexible models endowed with an interpretable latent structure that can be fit efficiently? I call this line of research deep probabilistic graphical modeling (DPGM). In this talk\, I will discuss my work on developing DPGM for text data. In particular\, I will show how DPGM enables flexible and interpretable topic modeling at large scale\, unlocking several known challenges. Furthermore\, I will describe how we can account for both local and long-range context\, under the DPGM framework\, to build a flexible sequential document model that leads to state-of-the-art performance on a downstream document classification task.
URL:https://seasevents.nmsdev7.com/event/cis-seminar-deep-probabilistic-graphical-modeling/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Colloquium
ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200318T013000
DTEND;TZID=America/New_York:20200318T143000
DTSTAMP:20260407T192143
CREATED:20200220T192156Z
LAST-MODIFIED:20200220T192156Z
UID:10006414-1584495000-1584541800@seasevents.nmsdev7.com
SUMMARY:Cancelled:  CIS Seminar:  "The Value Alignment Problem in Artificial Intelligence"
DESCRIPTION:Abstract: \nAbstract: Much of our success in artificial intelligence stems from the adoption of a simple paradigm: specify an objective or goal\, and then use optimization algorithms to identify a behavior (or predictor) that optimally achieves this goal. This has been true since the early days of AI (e.g.\, search algorithms such as A* that aim to find the optimal path to a goal state)\, and this paradigm is common to AI\, statistics\, control theory\, operations research\, and economics. Loosely speaking\, the field has evaluated the intelligence of an AI system by how efficiently and effectively it optimizes for its objective. This talk will provide an overview of my thesis work\, which proposes and explores the consequences of a simple\, but consequential\, shift in perspective: we should measure the intelligence of an AI system by its ability to optimize for our objectives. \n  \nIn an ideal world\, these measurements would be the same — all we have to do is write down the correct objective! This is easier said than done: misalignment between the behavior a system designer actually wants and the behavior incentivized by the reward or loss functions they specify is routine\, it is commonly observed in a wide variety of practical applications\, and fundamental\, as a consequence of limited human cognitive capacity. This talk will build up a formal model of this value alignment problem as a cooperative human-robot interaction: an assistance game of partial information between a human principal and an autonomous agent. It will begin with a discussion of a simple instantiation of this game where the human designer takes one action\, write down a proxy objective\, and the robot attempts to optimize for the true objective by treating the observed proxy as evidence about the intended goal. Next\, I will generalize this model to introduce Cooperative Inverse Reinforcement Learning\, a general and formal model of this assistance game\, and discuss the design of efficient algorithms to solve it. The talk will conclude with a discussion of directions for further research including applications to content recommendation and home robotics\, the development of reliable and robust design environments for AI objectives\, and the theoretical study of AI regulation by society as a value alignment problem with multiple human principals.
URL:https://seasevents.nmsdev7.com/event/cis-seminar-the-value-alignment-problem-in-artificial-intelligence/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Colloquium
ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200317T103000
DTEND;TZID=America/New_York:20200317T120000
DTSTAMP:20260407T192143
CREATED:20200225T212258Z
LAST-MODIFIED:20200225T212258Z
UID:10006419-1584441000-1584446400@seasevents.nmsdev7.com
SUMMARY:CANCELLED: MEAM Seminar: "Wind Farm Dynamics and Power Optimization in Realistic Atmospheric Boundary Layer Conditions"
DESCRIPTION:The study of wind farms within realistic atmospheric boundary layer conditions is critical to understand the governing physics of the system and to design optimal operational protocols. Historically\, control protocols have optimized performance of individual wind turbines resulting in aerodynamic wakes which typically reduce total wind farm power production 10-20% and increase the cost of electricity for this resource. Considering the wind farm as a collective\, we designed a physics- and data-driven wake steering control method to increase the power production of wind farms. The method was tested in a multi-turbine array at a utility-scale operational wind farm\, where it statistically significantly increased the power production over standard operation. The analytic gradient-based wind farm power optimization methodology we developed can optimize the yaw misalignment angles for large wind farms on the order of seconds\, enabling online real-time control. In order to rapidly design and improve dynamic closed-loop wind farm controllers\, we developed wind farm large eddy simulation capabilities that incorporate Coriolis and stratification effects. The traditional approximation made in typical simulations assumes that the horizontal component of Earth’s rotation is negligible in the atmospheric boundary layer. When including the horizontal component of Earth’s rotation\, the boundary layer and wind farm physics are a function of the geostrophic wind direction. The influence of the geostrophic wind direction on a wind farm atmospheric boundary layer was characterized using conventionally neutral and stable boundary layer simulations. Dynamic wake steering controllers are tested in simulations and\, altogether\, the results indicate that closed-loop wake steering control can significantly increase wind farm power production over greedy operation provided that site-specific wind farm data is assimilated into the optimal control model.
URL:https://seasevents.nmsdev7.com/event/meam-seminar-wind-farm-dynamics-and-power-optimization-in-realistic-atmospheric-boundary-layer-conditions/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200310T103000
DTEND;TZID=America/New_York:20200310T120000
DTSTAMP:20260407T192143
CREATED:20200302T172906Z
LAST-MODIFIED:20200302T172906Z
UID:10006423-1583836200-1583841600@seasevents.nmsdev7.com
SUMMARY:MEAM Seminar: "Scalable Algorithms for the Computational Modeling of Complex Multi-Physics Systems"
DESCRIPTION:The computational modeling of complex multi-physics problems often requires specialized approaches in the formulation\, implementation\, and deployment of algorithms that lie outside the scope of conventional practice in physics-based modeling and simulation. In this talk I will present three examples of problems in which the synergistic combination of advanced algorithms\, and state-of-the-art software implementations on hybrid hardware platforms can furnish computational frameworks with the ability to describe the complex physics involved. In each case\, the resulting simulations provide unique physical insights that would be otherwise unattainable\, thus enabling analyses of engineering significance. \nThe first example is concerned with the computational modeling of fluid-driven fracture propagation\, which is mired with major difficulties stemming from the strong nonlinearities in the fluid-solid coupling\, in addition to those associated with crack propagation\, and from the a priori unknown and potentially intricate 3D crack paths that may arise. I will show that the adoption of a discontinuous Galerkin finite element formulation for the solid\, combined with a sound cohesive zone model for crack propagation and a continuous formulation for the lubrication flow inside the propagating cracks\, results in a robust and scalable solution scheme\, which properly exposes the nonlinearities in the coupling\, thus preserving the parabolic nature of the coupled system. The proposed framework matches well-established analytical solutions of pressurized cracks in simple configurations both in the toughness and viscosity-dominated regimes\, and enables simulations of general crack configurations in 3D with unprecedented resolution for problem of this type. \nThe second example involves the modeling of elastic instabilities emerging in the large-deformation response of nearly incompressible soft materials\, where the non-convexity of the strain energy density leads to the coexistence of multiple equilibrium paths with vastly different\, sinuous deformation patterns. I will show that the numerical challenges involved can be overcome by an enhanced finite element solution space with higher order polynomials\, an arc-length-based nonlinear solution procedure which gives access to the entire equilibrium path\, and an implementation enabling parallel\, large-scale simulations. I will show that the robustness of the path-following solution procedure enables complete access to the multiplicity of solutions emerging after bifurcation\, to the complex non-monotonic evolution of the deformation patterns and of the stress-strain response\, as well as to the settled post-bifurcation states. \nTime permitting\, I will discuss the dynamics of multiple flexible fibers immersed in viscous flows. The very large deformations that the fibers experience\, especially in case of extreme aspect ratios\, make the fiber-fiber and fiber-flow interactions extraordinarily complex. Moreover\, the nonlocal character of these interactions results in dense linear systems and\, in turn\, in severe constraints to the problem size. I will present a computational model based on a general 3D beam formulation coupled with a boundary element Stokeslet discretization of the flow. The proposed computational framework takes advantage of the massive parallelization offered by GPU clusters\, and enables simulations of hundreds and\, possibly\, thousands of filaments.
URL:https://seasevents.nmsdev7.com/event/meam-seminar-scalable-algorithms-for-the-computational-modeling-of-complex-multi-physics-systems/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Seminar
ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200306T110000
DTEND;TZID=America/New_York:20200306T120000
DTSTAMP:20260407T192143
CREATED:20200207T172144Z
LAST-MODIFIED:20200207T172144Z
UID:10006404-1583492400-1583496000@seasevents.nmsdev7.com
SUMMARY:ESE Seminar: "Integrated Optical Phased Arrays: LiDAR\, Augmented Reality\, and Beyond"
DESCRIPTION:Abstract\nBy enabling optical microsystems with new functionalities\, improved system performance\, and reduced size\, weight\, and power\, integrated photonics is positioned to enable next-generation optical technologies that facilitate revolutionary advances for numerous fields spanning science and engineering\, including computing\, sensing\, communications\, displays\, quantum\, and biology. \nAn emerging class of integrated photonic systems is integrated optical phased arrays\, which enable manipulation and dynamic control of free-space light in a compact form factor\, at low costs\, and in a non-mechanical way. As such\, integrated optical phased arrays have emerged as a promising technology for many wide-reaching applications\, including light detection and ranging (LiDAR) for autonomous vehicles\, augmented-reality displays\, free-space optical communications\, and trapped-ion quantum computing. \nThis talk will present recent advances in integrated optical phased array architectures\, results\, and applications. First\, the first beam-steering optical phased arrays monolithically integrated with on-chip rare-earth-doped lasers and heterogeneously integrated with CMOS driving electronics will be shown and the first single-chip coherent integrated LiDAR results will be presented; these demonstrations are important steps towards practical commercialization of low-cost and high-performance integrated LiDAR sensors for autonomous vehicles. Next\, the first integrated optical phased arrays that focus radiated light to tightly- confined spots in the near field and that generate quasi-Bessel beams will be discussed; these near-field modalities have the potential to advance a number of application areas\, such as optical trapping for biological characterization\, trapped-ion quantum computing\, and laser-based 3D printing. Finally\, a novel transparent integrated-phased-array-based holographic display will be proposed as a highly-discreet and fully-holographic solution for the next generation of augmented-reality head-mounted displays; the first integrated passive near-eye displays that generate holograms\, the first integrated visible-light liquid crystal-based modulators\, and the first actively-tunable visible-light integrated phased arrays will be presented.
URL:https://seasevents.nmsdev7.com/event/ese-seminar-integrated-optical-phased-arrays-lidar-augmented-reality-and-beyond/
LOCATION:Berger Auditorium (Room 13)\, Skirkanich Hall\, 210 South 33rd Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Colloquium
ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200305T150000
DTEND;TZID=America/New_York:20200305T160000
DTSTAMP:20260407T192143
CREATED:20200220T190835Z
LAST-MODIFIED:20200220T190835Z
UID:10006413-1583420400-1583424000@seasevents.nmsdev7.com
SUMMARY:CIS Seminar: "Building Data-Driven Computers: Reimagining Systems to Reduce the High Costs of Large-Scale Data Processing"
DESCRIPTION:Abstract: \nA wide range of application domains are emerging as computing platforms of all types become more ubiquitous in society.  Many of these applications are data centric\, and spend a significant fraction of their time on accessing and processing very large datasets.  Examples of these applications include graph frameworks\, precision medicine\, computer vision\, deep learning\, and mobile device workloads.  Unfortunately\, the hardware platforms executing these applications remain compute centric\, and are rooted in decades-old design principles for computer architectures.  Running modern data-centric applications on compute-centric platforms results in high inefficiencies\, with significant energy waste and program stalls.  Data-centric platforms can eliminate these inefficiencies\, but require the community to fundamentally rethink our approach to computer design. \nIn this talk\, I will present a holistic approach for developing practical data-centric architectures and systems.  I will begin by using experimental characterization to identify the sources of poor energy efficiency and poor performance in existing architectures as they run modern applications\, focusing on the impact of current memory systems.  Next\, I will show how near-data computing can mitigate these inefficiencies.  Recent breakthroughs in memory technologies have made near-data computing a practical and viable alternative to compute-centric platforms\, but several system-level challenges remain.  I will present a few of my representative efforts towards developing practical programmer and architectural support for near-data computing\, including efficient data coherence and domain-specific system design.  I will conclude the talk with my future research vision\, on developing and building full-system data-driven architectures that are optimized for energy efficiency.  This includes microarchitectural and circuit-level support for in-memory computing using emerging non-volatile memories\, cooperative hardware–software memory management\, and compiler and data optimizations that allow programmers to effortlessly target these data-driven architectures. \n 
URL:https://seasevents.nmsdev7.com/event/cis-seminar-building-data-driven-computers-reimagining-systems-to-reduce-the-high-costs-of-large-scale-data-processing/
LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States
CATEGORIES:Colloquium
ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu
END:VEVENT
END:VCALENDAR