BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Penn Engineering Events - ECPv6.15.19//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-WR-CALNAME:Penn Engineering Events X-ORIGINAL-URL:https://seasevents.nmsdev7.com X-WR-CALDESC:Events for Penn Engineering Events REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:America/New_York BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20190310T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20191103T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20200308T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20201101T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20210314T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20211107T060000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=America/New_York:20200317T103000 DTEND;TZID=America/New_York:20200317T120000 DTSTAMP:20260408T031828 CREATED:20200225T212258Z LAST-MODIFIED:20200225T212258Z UID:10006419-1584441000-1584446400@seasevents.nmsdev7.com SUMMARY:CANCELLED: MEAM Seminar: "Wind Farm Dynamics and Power Optimization in Realistic Atmospheric Boundary Layer Conditions" DESCRIPTION:The study of wind farms within realistic atmospheric boundary layer conditions is critical to understand the governing physics of the system and to design optimal operational protocols. Historically\, control protocols have optimized performance of individual wind turbines resulting in aerodynamic wakes which typically reduce total wind farm power production 10-20% and increase the cost of electricity for this resource. Considering the wind farm as a collective\, we designed a physics- and data-driven wake steering control method to increase the power production of wind farms. The method was tested in a multi-turbine array at a utility-scale operational wind farm\, where it statistically significantly increased the power production over standard operation. The analytic gradient-based wind farm power optimization methodology we developed can optimize the yaw misalignment angles for large wind farms on the order of seconds\, enabling online real-time control. In order to rapidly design and improve dynamic closed-loop wind farm controllers\, we developed wind farm large eddy simulation capabilities that incorporate Coriolis and stratification effects. The traditional approximation made in typical simulations assumes that the horizontal component of Earth’s rotation is negligible in the atmospheric boundary layer. When including the horizontal component of Earth’s rotation\, the boundary layer and wind farm physics are a function of the geostrophic wind direction. The influence of the geostrophic wind direction on a wind farm atmospheric boundary layer was characterized using conventionally neutral and stable boundary layer simulations. Dynamic wake steering controllers are tested in simulations and\, altogether\, the results indicate that closed-loop wake steering control can significantly increase wind farm power production over greedy operation provided that site-specific wind farm data is assimilated into the optimal control model. URL:https://seasevents.nmsdev7.com/event/meam-seminar-wind-farm-dynamics-and-power-optimization-in-realistic-atmospheric-boundary-layer-conditions/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200310T103000 DTEND;TZID=America/New_York:20200310T120000 DTSTAMP:20260408T031828 CREATED:20200302T172906Z LAST-MODIFIED:20200302T172906Z UID:10006423-1583836200-1583841600@seasevents.nmsdev7.com SUMMARY:MEAM Seminar: "Scalable Algorithms for the Computational Modeling of Complex Multi-Physics Systems" DESCRIPTION:The computational modeling of complex multi-physics problems often requires specialized approaches in the formulation\, implementation\, and deployment of algorithms that lie outside the scope of conventional practice in physics-based modeling and simulation. In this talk I will present three examples of problems in which the synergistic combination of advanced algorithms\, and state-of-the-art software implementations on hybrid hardware platforms can furnish computational frameworks with the ability to describe the complex physics involved. In each case\, the resulting simulations provide unique physical insights that would be otherwise unattainable\, thus enabling analyses of engineering significance. \nThe first example is concerned with the computational modeling of fluid-driven fracture propagation\, which is mired with major difficulties stemming from the strong nonlinearities in the fluid-solid coupling\, in addition to those associated with crack propagation\, and from the a priori unknown and potentially intricate 3D crack paths that may arise. I will show that the adoption of a discontinuous Galerkin finite element formulation for the solid\, combined with a sound cohesive zone model for crack propagation and a continuous formulation for the lubrication flow inside the propagating cracks\, results in a robust and scalable solution scheme\, which properly exposes the nonlinearities in the coupling\, thus preserving the parabolic nature of the coupled system. The proposed framework matches well-established analytical solutions of pressurized cracks in simple configurations both in the toughness and viscosity-dominated regimes\, and enables simulations of general crack configurations in 3D with unprecedented resolution for problem of this type. \nThe second example involves the modeling of elastic instabilities emerging in the large-deformation response of nearly incompressible soft materials\, where the non-convexity of the strain energy density leads to the coexistence of multiple equilibrium paths with vastly different\, sinuous deformation patterns. I will show that the numerical challenges involved can be overcome by an enhanced finite element solution space with higher order polynomials\, an arc-length-based nonlinear solution procedure which gives access to the entire equilibrium path\, and an implementation enabling parallel\, large-scale simulations. I will show that the robustness of the path-following solution procedure enables complete access to the multiplicity of solutions emerging after bifurcation\, to the complex non-monotonic evolution of the deformation patterns and of the stress-strain response\, as well as to the settled post-bifurcation states. \nTime permitting\, I will discuss the dynamics of multiple flexible fibers immersed in viscous flows. The very large deformations that the fibers experience\, especially in case of extreme aspect ratios\, make the fiber-fiber and fiber-flow interactions extraordinarily complex. Moreover\, the nonlocal character of these interactions results in dense linear systems and\, in turn\, in severe constraints to the problem size. I will present a computational model based on a general 3D beam formulation coupled with a boundary element Stokeslet discretization of the flow. The proposed computational framework takes advantage of the massive parallelization offered by GPU clusters\, and enables simulations of hundreds and\, possibly\, thousands of filaments. URL:https://seasevents.nmsdev7.com/event/meam-seminar-scalable-algorithms-for-the-computational-modeling-of-complex-multi-physics-systems/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200306T110000 DTEND;TZID=America/New_York:20200306T120000 DTSTAMP:20260408T031828 CREATED:20200207T172144Z LAST-MODIFIED:20200207T172144Z UID:10006404-1583492400-1583496000@seasevents.nmsdev7.com SUMMARY:ESE Seminar: "Integrated Optical Phased Arrays: LiDAR\, Augmented Reality\, and Beyond" DESCRIPTION:Abstract\nBy enabling optical microsystems with new functionalities\, improved system performance\, and reduced size\, weight\, and power\, integrated photonics is positioned to enable next-generation optical technologies that facilitate revolutionary advances for numerous fields spanning science and engineering\, including computing\, sensing\, communications\, displays\, quantum\, and biology. \nAn emerging class of integrated photonic systems is integrated optical phased arrays\, which enable manipulation and dynamic control of free-space light in a compact form factor\, at low costs\, and in a non-mechanical way. As such\, integrated optical phased arrays have emerged as a promising technology for many wide-reaching applications\, including light detection and ranging (LiDAR) for autonomous vehicles\, augmented-reality displays\, free-space optical communications\, and trapped-ion quantum computing. \nThis talk will present recent advances in integrated optical phased array architectures\, results\, and applications. First\, the first beam-steering optical phased arrays monolithically integrated with on-chip rare-earth-doped lasers and heterogeneously integrated with CMOS driving electronics will be shown and the first single-chip coherent integrated LiDAR results will be presented; these demonstrations are important steps towards practical commercialization of low-cost and high-performance integrated LiDAR sensors for autonomous vehicles. Next\, the first integrated optical phased arrays that focus radiated light to tightly- confined spots in the near field and that generate quasi-Bessel beams will be discussed; these near-field modalities have the potential to advance a number of application areas\, such as optical trapping for biological characterization\, trapped-ion quantum computing\, and laser-based 3D printing. Finally\, a novel transparent integrated-phased-array-based holographic display will be proposed as a highly-discreet and fully-holographic solution for the next generation of augmented-reality head-mounted displays; the first integrated passive near-eye displays that generate holograms\, the first integrated visible-light liquid crystal-based modulators\, and the first actively-tunable visible-light integrated phased arrays will be presented. URL:https://seasevents.nmsdev7.com/event/ese-seminar-integrated-optical-phased-arrays-lidar-augmented-reality-and-beyond/ LOCATION:Berger Auditorium (Room 13)\, Skirkanich Hall\, 210 South 33rd Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Colloquium ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200305T150000 DTEND;TZID=America/New_York:20200305T160000 DTSTAMP:20260408T031828 CREATED:20200220T190835Z LAST-MODIFIED:20200220T190835Z UID:10006413-1583420400-1583424000@seasevents.nmsdev7.com SUMMARY:CIS Seminar: "Building Data-Driven Computers: Reimagining Systems to Reduce the High Costs of Large-Scale Data Processing" DESCRIPTION:Abstract: \nA wide range of application domains are emerging as computing platforms of all types become more ubiquitous in society.  Many of these applications are data centric\, and spend a significant fraction of their time on accessing and processing very large datasets.  Examples of these applications include graph frameworks\, precision medicine\, computer vision\, deep learning\, and mobile device workloads.  Unfortunately\, the hardware platforms executing these applications remain compute centric\, and are rooted in decades-old design principles for computer architectures.  Running modern data-centric applications on compute-centric platforms results in high inefficiencies\, with significant energy waste and program stalls.  Data-centric platforms can eliminate these inefficiencies\, but require the community to fundamentally rethink our approach to computer design. \nIn this talk\, I will present a holistic approach for developing practical data-centric architectures and systems.  I will begin by using experimental characterization to identify the sources of poor energy efficiency and poor performance in existing architectures as they run modern applications\, focusing on the impact of current memory systems.  Next\, I will show how near-data computing can mitigate these inefficiencies.  Recent breakthroughs in memory technologies have made near-data computing a practical and viable alternative to compute-centric platforms\, but several system-level challenges remain.  I will present a few of my representative efforts towards developing practical programmer and architectural support for near-data computing\, including efficient data coherence and domain-specific system design.  I will conclude the talk with my future research vision\, on developing and building full-system data-driven architectures that are optimized for energy efficiency.  This includes microarchitectural and circuit-level support for in-memory computing using emerging non-volatile memories\, cooperative hardware–software memory management\, and compiler and data optimizations that allow programmers to effortlessly target these data-driven architectures. \n  URL:https://seasevents.nmsdev7.com/event/cis-seminar-building-data-driven-computers-reimagining-systems-to-reduce-the-high-costs-of-large-scale-data-processing/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Colloquium ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200305T120000 DTEND;TZID=America/New_York:20200305T130000 DTSTAMP:20260408T031828 CREATED:20200109T163814Z LAST-MODIFIED:20200109T163814Z UID:10006367-1583409600-1583413200@seasevents.nmsdev7.com SUMMARY:BE Seminar: "Engineering Stem Cells to Create Novel Delivery Vehicles" DESCRIPTION:Synthetic biology has transformed how cells can be reprogrammed\, providing a means to reliably and predictably control cell behavior with the assembly of genetic parts into more complex gene circuits. Using approaches and tools in synthetic biology\, we are programming stem cells with novel genetic tools to control genes and pathways that result in changes in stem cell fate decisions\, in addition to reprogramming terminally differentiated cells to function as unique therapeutic diagnostic and delivery vehicles. URL:https://seasevents.nmsdev7.com/event/be-seminar-title-tbc-3/ LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Bioengineering":MAILTO:be@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200305T110000 DTEND;TZID=America/New_York:20200305T120000 DTSTAMP:20260408T031828 CREATED:20200205T155655Z LAST-MODIFIED:20200205T155655Z UID:10006398-1583406000-1583409600@seasevents.nmsdev7.com SUMMARY:ESE Seminar: "Joint Wireless Communication and Sensing in Terahertz Spectrum" DESCRIPTION:Abstract\nMillimeter-wave and terahertz bands are emerging as the most promising spectrum to meet the data-rate and latency demands of future wireless applications\, including virtual reality and autonomous cars. Moreover\, large spectral availability and mm-scale wavelength provide the possibility for ubiquitous and high-resolution sensing. My research builds a foundation for joint communication and sensing in such high-frequency regimes. This perspective yields a paradigm shift in the design and development of future wireless systems. In this talk\, I will present the world’s first single-shot and single-antenna motion sensing system in THz bands. We demonstrate a novel node architecture exploiting a single leaky wave antenna\, which is primarily used for beam steering in THz networks. I will show how we leverage this device’s spatial-spectral characteristics in new ways to enable motion sensing functionalities with a single THz pulse transmission. I will then discuss the opportunities offered by this platform to enhance next-generation communication in unprecedented ways. In particular\, we tackle the mobility\, blockage\, and scalability challenges of highly directional THz networks by efficiently adapting steering direction for mobile users. Finally\, I will share several research directions that I would like to pursue in the future. URL:https://seasevents.nmsdev7.com/event/ese-seminar-joint-wireless-communication-and-sensing-in-terahertz-spectrum/ LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Colloquium ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200303T150000 DTEND;TZID=America/New_York:20200303T160000 DTSTAMP:20260408T031828 CREATED:20200219T201529Z LAST-MODIFIED:20200219T201529Z UID:10006412-1583247600-1583251200@seasevents.nmsdev7.com SUMMARY:CIS Seminar: "Breaking and Building End-to-End Encrypted Systems" DESCRIPTION:Abstract\n\nToday’s computer systems and their owners fail to protect data. Exacerbating this are new threats stemming from the rise of cloud computing. The consequences are dire: sensitive information like financial statements\, medical records\, and private messages are disclosed to malicious parties. In my research at the intersection of security\, cryptography\, and systems\, I work to change this by breaking and building efficient end-to-end (E2E) encrypted systems\, which protect data by keeping it encrypted throughout processing and storage. In this talk\, I’ll explain some of the flaws I’ve found in existing E2E-encrypted systems deployed to billions of users\, how the flaws have led me to a new methodology for building these systems that’s rooted in co-design of cryptography and systems\, and some of the new E2E-encrypted systems I’m building. URL:https://seasevents.nmsdev7.com/event/cis-seminar-breaking-and-building-end-to-end-encrypted-systems/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Colloquium END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200303T110000 DTEND;TZID=America/New_York:20200303T120000 DTSTAMP:20260408T031828 CREATED:20200205T154508Z LAST-MODIFIED:20200205T154508Z UID:10006397-1583233200-1583236800@seasevents.nmsdev7.com SUMMARY:ESE Seminar: "Safe Real-World Autonomy in Uncertain and Unstructured Environments" DESCRIPTION:Abstract \nIn this talk I will present my current and future work towards enabling safe real-world autonomy. My core focus is to enable efficient and safe decision-making in complex autonomous systems\, while reasoning about uncertainty in real-world environments\, including those involving human interactions. \nFirst I will discuss safety for complex systems in simple environments. Traditional methods for generating safety analyses and safe controllers struggle to handle realistic complex models of autonomous systems\, and therefore are stuck with simplistic models that are less accurate. I have developed scalable techniques for theoretically sound safety guarantees that can reduce computation by orders of magnitude for high-dimensional systems\, resulting in better safety analyses and paving the way for safety in real-world autonomy. \nNext I will add in complex environments. Safety analyses depend on pre-defined assumptions that will often be wrong in practice\, as real-world systems will inevitably encounter incomplete knowledge of the environment and other agents. Reasoning efficiently and safely in unstructured environments is an area where humans excel compared to current autonomous systems. Inspired by this\, I have used models of human decision-making from cognitive science to develop algorithms that allow autonomous systems to navigate quickly and safely\, adapt to new information\, and reason over the uncertainty inherent in predicting humans and other agents. Combining these techniques brings us closer to the goal of safe real-world autonomy. URL:https://seasevents.nmsdev7.com/event/ese-seminar-safe-real-world-autonomy-in-uncertain-and-unstructured-environments/ LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Colloquium ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200303T103000 DTEND;TZID=America/New_York:20200303T120000 DTSTAMP:20260408T031828 CREATED:20200226T145623Z LAST-MODIFIED:20200226T145623Z UID:10006422-1583231400-1583236800@seasevents.nmsdev7.com SUMMARY:MEAM Seminar: "Multiscale Interactions in Multiphase Turbulent Flows: Fundamentals to Applications" DESCRIPTION:Recent advances in experimental measurements and numerical simulations has allowed us to discover new phenomena in multiphase turbulence (a flow regime characterized by chaotic and irregular motion in the presence of immersed surfaces/bodies). In this talk\, I will discuss some of these new discoveries and their importance both from a fundamental and an application viewpoint. I will first present our finding of a surprising fluctuation-induced force between two plates immersed in a turbulent fluid. The mechanism of force generation reveals an intriguing analogy with the quantum Casimir effect. Next\, I will discuss how multiscale interactions between immersed bodies/surfaces and a carrier turbulent fluid can lead to drag reduction in the context of Taylor-Couette flows. I will conclude by showing some recent advances in our understanding of the role of turbulence in bio-physical flows (e.g. Cardio-vascular flow). URL:https://seasevents.nmsdev7.com/event/meam-seminar-multiscale-interactions-in-multiphase-turbulent-flows-fundamentals-to-applications/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200228T140000 DTEND;TZID=America/New_York:20200228T150000 DTSTAMP:20260408T031828 CREATED:20191216T200711Z LAST-MODIFIED:20191216T200711Z UID:10006348-1582898400-1582902000@seasevents.nmsdev7.com SUMMARY:PICS Seminar - Dr. Cesar de la Fuente of the University of Pennsylvania\, Perelman School of Medicine DESCRIPTION:Abstract: \nUntil now\, the natural world has supplied us with antibiotics. Bacteria\, however\, are increasingly resistant to these drugs. The next generation of antibiotics will likely come not from nature but from computer-based discovery. Working at the forefront of this development\, I seek to harness computational power to find molecules with antibacterial activity. I use synthetic biology and computational tools to determine features contributing to this activity and train computers to find— or design— candidate molecules and tweak their structures virtually. Experimentation is reserved for validating computer predictions\, saving time\, labor\, and expense. With machine-based molecular discovery\, I explore proteins and peptides as engineering scaffolds. My approaches diversify proteins\, such as host defense peptides (HDPs)\, beyond their natural variation. For example\, to increase their antimicrobial properties\, we trained a computer to execute a fitness function that selects for structures that interact with bacterial membranes\, thereby converting several HDPs into the first artificial antimicrobials that kill bacteria both in vitro and in animals. By investigating these exciting possibilities\, I aim to build machine-made antibiotics to combat infectious diseases and develop clinical applications for autonomously generated synthetic molecules. Computer-made drugs may help to replenish our arsenal of effective drugs and outpace the evolution of antibiotic resistance. URL:https://seasevents.nmsdev7.com/event/pics-seminar-with-dr-cesar-de-la-fuente-of-the-university-of-pennsylvania-perelman-school-of-medicine/ LOCATION:PICS Conference Room 534 – A Wing \, 5th Floor\, 3401 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar,Colloquium ORGANIZER;CN="Penn Institute for Computational Science (PICS)":MAILTO:dkparks@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200227T150000 DTEND;TZID=America/New_York:20200227T160000 DTSTAMP:20260408T031828 CREATED:20200219T192722Z LAST-MODIFIED:20200219T192722Z UID:10006411-1582815600-1582819200@seasevents.nmsdev7.com SUMMARY:CIS Seminar: "Risk-Aware Machine Learning at Scale" DESCRIPTION:Abstract: \n\nIn recent years\, machine learning has seen rapid advances with increasingly large scale and complex data modalities\, including processing images\, natural language and more. As a result\, applications of machine learning have pervaded our lives to make them easier and more convenient. Buoyed by this success\, we are approaching an era where machine learning will be used to autonomously make increasingly risky decisions that impact the physical world and risk life\, limb\, and property. For example\, machine learning may autonomously decide when cars should brake or swerve\, how power should be allocated in smart grids\, what treatments to recommend in some medical settings and much more. \nIn this talk\, I will discuss how we can begin to understand and mitigate this risk. In particular\, I will focus on how we can combine lessons learned from the unprecedented practical success of deep learning with approaches from statistical and probabilistic machine learning to make risk aware decisions in practice and at scale. I will show how one popular probabilistic method\, Gaussian process regression\, can be made to scale without approximation to millions of training examples for complex tasks despite traditionally being limited to thousands. Finally. I will discuss a number of examples where these tools are deployed successfully in practice\, and conclude with a discussion of the most important problems and limitations I believe we have yet to face in this area. URL:https://seasevents.nmsdev7.com/event/cis-seminar-risk-aware-machine-learning-at-scale/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Colloquium END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200227T120000 DTEND;TZID=America/New_York:20200227T130000 DTSTAMP:20260408T031828 CREATED:20200109T163541Z LAST-MODIFIED:20200109T163541Z UID:10006366-1582804800-1582808400@seasevents.nmsdev7.com SUMMARY:BE Seminar: "Musculoskeletal Tissue Engineering" DESCRIPTION: URL:https://seasevents.nmsdev7.com/event/be-seminar-title-tbc-2/ LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Bioengineering":MAILTO:be@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200227T110000 DTEND;TZID=America/New_York:20200227T120000 DTSTAMP:20260408T031828 CREATED:20200213T150450Z LAST-MODIFIED:20200213T150450Z UID:10006408-1582801200-1582804800@seasevents.nmsdev7.com SUMMARY:ESE Seminar: "Engineering Quantum Processors in Silicon" DESCRIPTION:Abstract\nAcross the globe\, physicists in academia and industry alike are competing to be the first to build a scalable universal quantum computer. Amongst the multitudes of quantum computing architectures\, solid-state quantum processors based on spins in silicon are emerging as a strong contender. Silicon is an ideal material to host spin qubits: it supports long coherence times [1]\, has excellent prospects for scaling\, and is ubiquitous in the semiconductor industry. While semiconductor spin qubits were proposed over two decades ago [2]\, it is only within the past few years that we have learned how to fabricate and control multi-qubit devices in silicon. \nIn this seminar\, I will describe our state-of-the-art four-qubit Si/SiGe quantum dot device [3] and explain how we have overcome major barriers to realizing large-scale quantum computing in silicon. First\, I will discuss charge control and spin-state readout in the device. Then\, I will describe the use of an on-chip micromagnet to mediate electrically driven spin resonance [4-5]. Using this technique\, we achieve site-selective spin control with fidelities exceeding 99.9%. I will outline the operation of our three primitive two-qubit gates: the decoupled-CZ gate [4]\, the resonant CNOT gate [5]\, and the resonant SWAP gate [6]. Finally\, I will discuss how these advances enable the development of large-scale quantum processors capable of complex quantum information processing. \nReferences:\n[1] Tyryshkin et al.\, Nature Mat. 11\, 143 (2011)\n[2] Loss and Divincenzo\, Phys. Rev. A 57\, 120 (1998)\n[3] Sigillito et al.\, Phys. Rev. Applied 11\, 061006 (2019)\n[4] Watson et al.\, Nature 555\, 633 (2018)\n[5] Zajac\, Sigillito\, et al.\, Science 359\, 439 (2018)\n[6] Sigillito et al.\, npj Quantum Information 5\, 110 (2019) URL:https://seasevents.nmsdev7.com/event/ese-seminar-engineering-quantum-processors-in-silicon/ LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Colloquium ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200227T104500 DTEND;TZID=America/New_York:20200227T114500 DTSTAMP:20260408T031828 CREATED:20200214T204654Z LAST-MODIFIED:20200214T204654Z UID:10006410-1582800300-1582803900@seasevents.nmsdev7.com SUMMARY:MSE Faculty Candidate Seminar: “Computational Materials Design from Synthesis to Functionality” DESCRIPTION:The concept of computational materials design envisions the identification of new synthetically-accessible structures with desirable properties and the optimization of known systems using first-principles calculations. While significant steps towards realizing this vision have been made\, notably in atomistic property evaluation\, the computational prediction of materials synthesis and realistic structure remains a challenge. Dr. Kitchaev will describe my work towards resolving these obstacles using three examples where models constructed from first-principles data yield quantitative synthesis predictions\, describe the structure of the resulting materials\, and reveal design criteria for optimizing materials behavior. He will first show that the synthesis routes used to obtain the diverse array of crystal structures observed in the manganese oxides can be quantitatively described with a quasi-equilibrium view of crystallization which takes into account the effects of off-stoichiometry\, finite-size effects and hydration. He will then apply a similar synthesis model to the design and optimization of disordered rocksalt oxyfluoride Li-ion battery cathode materials where electrochemical behavior is strongly coupled to chemical short range order. Finally\, he will describe the computational design of materials capable of hosting magnetic skyrmion phases\, which are nanoscale magnetic textures with nontrivial topology\, focusing on ensuring that these phases are thermally robust and tunable as is necessary for spintronic device applications. In all three cases\, experimental tests validate the predictive power of the computational analysis. While numerous open questions remain to be resolved before generally predictive synthesis-aware materials design is possible\, these initial results demonstrate the transformative potential of these tools to the development of new functional materials. URL:https://seasevents.nmsdev7.com/event/mse-faculty-candidate-seminar-computational-materials-design-from-synthesis-to-functionality/ LOCATION:Auditorium\, LRSM Building\, 3231 Walnut Street\, Philadelphia\, PA\, 19104\, United States ORGANIZER;CN="Materials Science and Engineering":MAILTO:johnruss@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200226T150000 DTEND;TZID=America/New_York:20200226T160000 DTSTAMP:20260408T031828 CREATED:20191219T204400Z LAST-MODIFIED:20191219T204400Z UID:10006354-1582729200-1582732800@seasevents.nmsdev7.com SUMMARY:CBE Faculty Candidate Seminar: "Understanding and Design of Materials of High Energy Density Batteries" DESCRIPTION:Abstract: \nEnvironmental challenges and economic forces are reshaping the way we generate and consume energy on a global scale. To keep up with the accelerating adoption of electric vehicles\, allow for grid scale energy storage\, and meet the demands of future technological advances\, new materials for high energy density batteries must be developed. High costs have prevented widespread deployment of lithium-ion batteries beyond portable electronics\, and the safety hazards of exothermic reactions associated with traditional materials during cell failure remain to be fully addressed. Therefore\, strategies to enhance the mechanical and chemical stability of next-generation electrode materials are key to the successful integration of batteries into our future energy systems. In this presentation\, I will discuss new materials designed to address issues of stability in Li-ion batteries and fundamental insight into the mechanisms of this stabilization. The first portion of my talk will describe how a supramolecular\, hydrogen-bonding\, self-healing polymer is used to stabilize high capacity anode materials. Next\, I will describe further investigation toward a general understanding of how polymer coatings affect the electrodeposition of metallic lithium anodes. Third\, I will discuss the use of in situ characterization techniques to study the mechanisms of electrolyte decomposition reactions at the lithium metal interface. Overall\, the work presented here contributes new materials to be used in electric vehicles\, grid scale storage\, and new electronic devices\, and uses these materials to develop a fundamental understanding about how materials properties affect the stability of lithium ion batteries in each application. This understanding provides direction for the design and synthesis of new polymer materials to better stabilize advanced battery chemistries. URL:https://seasevents.nmsdev7.com/event/cbe-seminar-understanding-and-design-of-materials-of-high-energy-density-batteries/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200226T090000 DTEND;TZID=America/New_York:20200226T220000 DTSTAMP:20260408T031828 CREATED:20200225T213737Z LAST-MODIFIED:20200225T213737Z UID:10006420-1582707600-1582754400@seasevents.nmsdev7.com SUMMARY:“Engineering at NSF: Big Ideas and More” DESCRIPTION:Three years ago\, NSF announced Ten Big Ideas for Future Investments. From Harnessing the Data Revolution\, to defining the Future of Work at the Human-Technology Frontier\, and Understanding the Rules of Life\, all of the Big Ideas require cross-disciplinary\, convergent research to make significant progress on these important societal challenges. The talk will present an overview of these ideas and describe some of the funding opportunities. There will also be a summary of the activities of the Engineering Directorate\, highlights of new cross-cutting programs at NSF\, and time for Q&A. URL:https://seasevents.nmsdev7.com/event/engineering-at-nsf-big-ideas-and-more/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200225T143000 DTEND;TZID=America/New_York:20200225T170000 DTSTAMP:20260408T031828 CREATED:20200127T184902Z LAST-MODIFIED:20200127T184902Z UID:10006390-1582641000-1582650000@seasevents.nmsdev7.com SUMMARY:Memorial Event: Dean Joseph Bordogna DESCRIPTION:Please join us on Tuesday\, February 25\, as we celebrate the life and legacy of Dr. Joseph Bordogna\, Professor Emeritus of Electrical and Systems Engineering and former Dean of Penn Engineering. \nDr. Bordogna was a student and a colleague in our school\, and a beloved and visionary dean. He provided the foundational leadership for the world-renowned M&T program\, was a champion of K-12 education\, and a founder of PRIME (Philadelphia Regional Introduction for Minorities to Engineering). He was an officer on the USS New Jersey\, which is anchored here in Philadelphia. He served as the deputy director and Chief Operating Officer of the National Science Foundation from 1999-2005. Most importantly\, he was a true friend\, colleague and mentor to so many. \nA memorial celebration will be held in the Glandt Forum at the Singh Center for Nanotechnology\, followed by a reception in the Lubin Galleria. We hope you can attend. \n  URL:https://seasevents.nmsdev7.com/event/memorial-event-dean-joseph-bordogna/ LOCATION:Glandt Forum\, Singh Center for Nanotechnology\, 3205 Walnut Street\, Philadelphia\, PA\, 19104\, United States END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200225T110000 DTEND;TZID=America/New_York:20200225T120000 DTSTAMP:20260408T031828 CREATED:20200211T144540Z LAST-MODIFIED:20200211T144540Z UID:10006405-1582628400-1582632000@seasevents.nmsdev7.com SUMMARY:ESE Seminar: "Quantum information processing with superconducting circuits: Purcell effect and the measurement problem" DESCRIPTION:Abstract\nWith recent advances in state preparation\, gate\, and measurement operations\, superconducting circuit architectures are now leading candidates for quantum information processing. As micro-fabricated circuits are scaled up towards a practical quantum processor\, strict requirements on the fidelity of operations required for quantum computation are imposed. For theorists\, this mandates the development of accurate models describing the dynamics of complex superconducting circuits subject to strong drives. \nThis talk will begin with an elementary introduction to such systems and their description in terms of quantum electrodynamics\, the fundamental theory of light-matter interactions. We will then address the problem of the Purcell effect\, which is the enhancement of the decay rate of a single qubit due to a linear electromagnetic environment\, and show how convergent results can be obtained without any artificial high-frequency cutoffs. We will also explain how the Purcell rate is further enhanced in the presence of the drive fields typically used to measure qubits\, which is a ubiquitous problem encountered in present-day experiments. URL:https://seasevents.nmsdev7.com/event/ese-seminar-quantum-information-processing-with-superconducting-circuits-purcell-effect-and-the-measurement-problem/ CATEGORIES:Colloquium ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200225T103000 DTEND;TZID=America/New_York:20200225T120000 DTSTAMP:20260408T031828 CREATED:20200108T214751Z LAST-MODIFIED:20200108T214751Z UID:10006364-1582626600-1582632000@seasevents.nmsdev7.com SUMMARY:MEAM Seminar: "Robot Design Concepts for Intuitive Physical Human-Robot Interaction" DESCRIPTION:Physical human-robot interaction (pHRI) aims at taking advantage of the complementary capabilities of robots and humans. One of the key challenges in pHRI is to provide a high-bandwidth human-robot interaction that is safe and intuitive for the human user. To this end\, it is proposed in this work to revisit the design of robots in order to provide a low-impedance mechanical interaction. The concept of macro-mini robotic system is used and applied to interactive robotic devices. Also\, the design of backdrivable redundant parallel robots is considered. In this concept\, parallel robots are used to provide backdrivability while kinematic redundancy is introduced to increase the rotational workspace of parallel mechanisms\, by alleviating the singularities. Solutions based on passive or active human-robot interfaces are proposed and examples of implementations are described. Prototypes of robotic systems developed at Université Laval based on the above concepts are demonstrated. URL:https://seasevents.nmsdev7.com/event/meam-seminar-robot-design-concepts-for-intuitive-physical-human-robot-interaction-2/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200224T150000 DTEND;TZID=America/New_York:20200224T160000 DTSTAMP:20260408T031828 CREATED:20200128T150548Z LAST-MODIFIED:20200128T150548Z UID:10006391-1582556400-1582560000@seasevents.nmsdev7.com SUMMARY:CBE Faculty Candidate Seminar: Towards a "Greener" Route for Acetic Acid Production via the Carbonylation of Dimethyl Ether Over Small-Pore Molecular Sieves DESCRIPTION:Abstract: \nCatalyst design is a critical pillar\, and current bottleneck\, in the construction of a sustainable chemical industry. Practical catalytic materials are earth-abundant\, active\, selective\, and stable. Developing materials that meet these criteria is challenging and involves a two-phase process that (1) extracts molecular-level understanding of the origin of reactivity for a given chemical pathway\, and (2) exploits this understanding through tailored synthetic techniques. \nIn this talk\, I will focus on catalyst design for the Koch-type carbonylation pathway\, a reaction that is of practical interest since it provides a rare noble metal- and halide-free route to producing an important chemical intermediate\, acetic acid. I will present the characterization of the reactivity of the small-pore molecular sieve with the chabazite structure for this reaction. From the analysis of materials synthesized with different active site densities and strengths\, in conjunction with theoretical investigations\, we obtain fundamental insights into the descriptors of reactivity for the carbonylation reaction in this small-pore material. These insights\, in turn\, can be used to intelligently direct the investigation of other small-pore molecular sieves with tuned confining environments and chemical compositions\, and motivate the development of synthetic techniques that control active site distributions in a broader range of solid materials. Collectively\, our studies provide a successful example of the first step in the process of tailoring catalytic materials for new applications through rational design methods. URL:https://seasevents.nmsdev7.com/event/cbe-faculty-candidate-seminar-towards-a-greener-route-for-acetic-acid-production-via-the-carbonylation-of-dimethyl-ether-over-small-pore-molecular-sieves/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200221T140000 DTEND;TZID=America/New_York:20200221T150000 DTSTAMP:20260408T031828 CREATED:20200114T163710Z LAST-MODIFIED:20200114T163710Z UID:10006380-1582293600-1582297200@seasevents.nmsdev7.com SUMMARY:PICS Seminar with Sam Schoenholz of Google Brain DESCRIPTION: URL:https://seasevents.nmsdev7.com/event/pics-seminar-with-sam-schoenholz-of-google-brain/ LOCATION:PICS Conference Room 534 – A Wing \, 5th Floor\, 3401 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar,Colloquium ORGANIZER;CN="Penn Institute for Computational Science (PICS)":MAILTO:dkparks@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200220T104500 DTEND;TZID=America/New_York:20200220T114500 DTSTAMP:20260408T031828 CREATED:20200214T172446Z LAST-MODIFIED:20200214T172446Z UID:10006409-1582195500-1582199100@seasevents.nmsdev7.com SUMMARY:MSE Faculty Candidate Seminar: "Uncovering atomistic mechanisms of crystallization using Machine Learning" DESCRIPTION:Solid-liquid interfaces have notoriously haphazard atomic environments. While essentially amorphous\, the liquid has short-range order and heterogeneous dynamics. The crystal\, albeit ordered\, contains a plethora of defects ranging from adatoms to dislocation-created spiral steps. All these elements are of paramount importance in the crystal growth process\, which makes the crystallization kinetics challenging to describe concisely in a single framework. In this seminar I will introduce a novel data-driven approach to systematically detect\, encode\, and classify all atomic-scale crystallization mechanisms described above. I will also show how this approach naturally leads to a predictive kinetic model of crystallization that takes into account the entire zoo of microstructural elements present at solid-liquid interfaces. In this innovative application of data science to materials Machine Learning is employed as an aid to augment human intuition\, rather than a substitute thereof. The result is an approach that blends prevailing scientific methods with data-science tools to produce physically-consistent models and conceptual knowledge. URL:https://seasevents.nmsdev7.com/event/mse-faculty-candidate-seminar-uncovering-atomistic-mechanisms-of-crystallization-using-machine-learning/ LOCATION:Auditorium\, LRSM Building\, 3231 Walnut Street\, Philadelphia\, PA\, 19104\, United States ORGANIZER;CN="Materials Science and Engineering":MAILTO:johnruss@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200219T163000 DTEND;TZID=America/New_York:20200219T173000 DTSTAMP:20260408T031828 CREATED:20200129T192922Z LAST-MODIFIED:20200129T192922Z UID:10006393-1582129800-1582133400@seasevents.nmsdev7.com SUMMARY:The Joy of Being Faculty PT II: How I Devised My Research Program DESCRIPTION:This professional development workshop series is designed to provide Penn Engineering graduate students and postdocs with a richer understanding of what it is like to pursue a career in academia from those that have navigated the process successfully. Deputy Dean Kathleen J. Stebe (SEAS) will lead this extemporaneous discussion with a panel of Penn Engineering professors. Networking reception to follow. URL:https://seasevents.nmsdev7.com/event/the-joy-of-being-faculty-pt-ii-how-i-devised-my-research-program/ LOCATION:Glandt Forum\, Singh Center for Nanotechnology\, 3205 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Doctoral,Graduate,Panel Discussion,Postdoctoral END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200219T150000 DTEND;TZID=America/New_York:20200219T160000 DTSTAMP:20260408T031828 CREATED:20191219T203405Z LAST-MODIFIED:20191219T203405Z UID:10006353-1582124400-1582128000@seasevents.nmsdev7.com SUMMARY:CBE Faculty Candidate Seminar: Decomposition: Exploiting Structure in Chemical Systems to Solve Challenging Decision-Making Problems" DESCRIPTION:Abstract: \nComputational optimal decision-making tools are essential for ensuring that systems are designed\, operated\, and controlled in an economic and sustainable manner. Using optimization to make decisions for chemical and energy systems is particularly challenging due to the inherent presence of nonlinear process physics\, both integer and continuous decisions\, uncertainties in important parameters\, and multiple relevant time scales. This talk addresses the method of decomposition\, which solves large\, computationally challenging decision-making problems through a set of smaller\, easier-to-solve subproblems. The first half of this talk addresses the problem of identifying smaller subproblems that make the large problem easy to solve. An algorithmic framework for automatically doing so using community detection\, a concept from network theory\, is presented. The superiority of using community-based decompositions to solve optimization problems\, compared to other intuition-based decompositions\, is showcased through an optimal model predictive control case study. The ability of the algorithm to identify subproblems when an intuitive decomposition does not exist is also demonstrated. The second part of the talk addresses the challenge of coordinating subproblems to arrive at a solution of the original problem. Here\, a branch-and-price algorithm which can solve certain classes of nonconvex mixed integer nonlinear programs (the most challenging type of optimization problem to solve) to global optimality is presented. The applicability of this algorithm to many problems of chemical engineering interest\, including process design under uncertainty\, multiperiod capacity planning\, dynamic facility location\, and task assignment to process units\, is demonstrated. URL:https://seasevents.nmsdev7.com/event/cbe-seminar-decomposition-exploiting-structure-in-chemical-systems-to-solve-challenging-decision-making-problems/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Chemical and Biomolecular Engineering":MAILTO:cbemail@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200219T133000 DTEND;TZID=America/New_York:20200219T143000 DTSTAMP:20260408T031828 CREATED:20200211T213758Z LAST-MODIFIED:20200211T213758Z UID:10006407-1582119000-1582122600@seasevents.nmsdev7.com SUMMARY:CIS Seminar: One Size Doesn’t Fit Anyone: Tailoring Digital Tools for Personal Health Journeys DESCRIPTION:Abstract \nPersonal technologies for everyday health management have the potential to transform healthcare by\nempowering individuals to engage in their own care\, scaffolding access to critical information\, and\nsupporting patient-centered decision-making. Currently\, many personal health tools often focus only on a\nsingle task or isolated event. However\, chronic illnesses are characterized by information needs and\nchallenges that shift over time; thus\, these illnesses are better defined as a dynamic trajectory than a series\nof singular events.\nIn this talk\, I discuss my work designing and implementing novel computing systems that: 1) support\nchronic illness trajectories and 2) reduce patients’ barriers to health information access. I’ll present my\napproach using personalized and adaptive content to connect individuals with timely and actionable\nfeedback. Using results from longitudinal field deployments\, I demonstrate the ability for these tools to\nfacilitate patients’ proactive health management and engagement in their care. I’ll also discuss the utility\nof this approach for encouraging to long-term engagement with health tools\, as evidenced by longitudinal\nusage patterns. I’ll conclude with opportunities for using personalization as a strategy to support other\ncomplex information tasks\, including the health management of illness trajectories in which uncertainty is\nparamount and the integration of machine learning models into clinical workflows. URL:https://seasevents.nmsdev7.com/event/cis-seminar-one-size-doesnt-fit-anyone-tailoring-digital-tools-for-personal-health-journeys/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200218T150000 DTEND;TZID=America/New_York:20200218T160000 DTSTAMP:20260408T031828 CREATED:20200130T155107Z LAST-MODIFIED:20200130T155107Z UID:10006394-1582038000-1582041600@seasevents.nmsdev7.com SUMMARY:Technology\, Business and Government Lecture Series: Aerospace Prizes Inspire the Five I's of Success DESCRIPTION:The United States’ future economic growth and competitiveness depend on our capacity to inno­vate. Americans believe that it is possible to create jobs in the aerospace and defense industry by doing what the United States does well\, which is cultivating the creativity and innovative processes developed by its people. Innovation and entrepreneurship in the aerospace and defense industries have historically kept the US at the forefront of technology advances\, which has spurred economic growth\, and created entirely new industries such as commercial transportation of cargo and humans\, uninhabited aerial systems for civilian and military missions\, and more recently private commercial space.  Where would we be without aviation pioneers and innovators such as Amelia Earhart\, Glenn L. Martin\, William Boeing\, Charles Lindbergh\, Igor Sikorsky and Elon Musk?  A key catalyst that inspires innovation and entrepreneurship in the aerospace field has been the establishment of aerospace prizes and competitions to accelerate the five I’s:  imagination\, invention\, innovation\, investment\, and impact.  This presentation details three aerospace prizes that not only advanced technology in the aerospace field\, but also spurred significant job growth and economic development in the United States.  More importantly\, these prizes often attracted a new generation of students and technology innovators to the field with the hope of becoming the first to win a prize\, while making a significant contribution to the aerospace field and to society. \nThis lecture is part of Penn Engineering’s Technology\, Business\, and Government Lecture Series. Recognizing an increasingly significant inter-relationship between the rapid growth of new technologies and the business and governmental sectors\, the Technology\, Business and Government Lecture Series brings distinguished individuals to Penn Engineering to interact with students and faculty on broad issues affecting technology and science\, research and policy. \n  URL:https://seasevents.nmsdev7.com/event/technology-business-and-government-lecture-series-darryll-j-pines/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200218T110000 DTEND;TZID=America/New_York:20200218T120000 DTSTAMP:20260408T031828 CREATED:20200207T164134Z LAST-MODIFIED:20200207T164134Z UID:10006403-1582023600-1582027200@seasevents.nmsdev7.com SUMMARY:ESE Seminar: "Nanophotonics: A High Bandwidth Optical Neural Interface" DESCRIPTION:Abstract\nLight is a powerful tool for interrogating and manipulating biological systems\, enabling targeted\nstimulation\, sensing\, and imaging. Optical methods such as optogenetics have transformed the study of\nneural circuits by making it possible to control neural activity using light. However\, there remains a critical\ndemand in research and medicine for miniaturized high resolution optical tools that can be embedded\ndeep within biological systems like the brain. The brain poses particular challenges due to the sheer\nnumber of densely packed interconnected neurons and the strong tissue scattering and absorption of\nlight. Nanophotonics\, or chip-scale optical circuits\, can enable unprecedented spatiotemporal resolution\nby leveraging nanoscale coherent control of a large set of optical channels within subwavelength\nwaveguides with high speed reconfiguration capability\, potential for integration with electronics\, and low-\ncost scalable manufacturability. This potential high bandwidth optical neural interface can be as thin as a\nfew neurons and have the ability to test spatial\, temporal\, and cell-type-specific aspects of neural\nencoding from cellular to system level within the brain. \nI will present the first implantable nanophotonic probe for optogenetic stimulation and recording of\nneurons in live mice. To achieve this\, we developed a reconfigurable visible nanophotonic platform based\non phase-controlled silicon nitride interferometric waveguide structures that can control cellular-sized\ncoherent emitters at blue wavelengths (peak of optogenetic actuators)\, far from traditional infrared\nwavelengths. This enabled a neural interface that can generate and read multi-neuron spike patterns\ndeep within the brain with single-cell and sub-millisecond resolution\, the highest resolution\nneuromodulation shown with an implantable probe. \nIn addition\, I will highlight two building blocks for future nanophotonic stimulation and sensing\ndevices that I developed using this platform: wide-angle chip-scale visible beam steering and multiplexing\nwithin a single waveguide by utilizing the transverse spatial degree-of-freedom of light. I will show how\nprecise phase control and novel nanoscale photonic design of these building blocks has been applied to\nemerging high bandwidth optical applications like portable display technology and quantum optical\nsystems. Finally\, I will present a future outlook towards a new generation of implantable and wearable\nbiomedical devices based on nanophotonic 3D light projection and sensing techniques including high-\ndimensional multiplexing\, volumetric beam shaping\, and quantum sensing. URL:https://seasevents.nmsdev7.com/event/ese-seminar-nanophotonics-a-high-bandwidth-optical-neural-interface/ LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Colloquium ORGANIZER;CN="Electrical and Systems Engineering":MAILTO:eseevents@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200218T103000 DTEND;TZID=America/New_York:20200218T120000 DTSTAMP:20260408T031828 CREATED:20200108T214119Z LAST-MODIFIED:20200108T214119Z UID:10006363-1582021800-1582027200@seasevents.nmsdev7.com SUMMARY:MEAM Seminar: "Cell Polarization and Growth" DESCRIPTION:Polarization is an essential behavior of living cells\, yet the dynamics of this symmetry-breaking process are not fully understood. We have developed a spatial stochastic model of cellular polarization during mating of Saccharomyces cerevisiae. Specifically we investigated the ability of yeast cells to sense a spatial gradient of mating pheromone and respond by forming a projection in the direction of the mating partner. Our results demonstrate that a spatial stochastic model of polarisome formation can more robustly reproduce two fundamental characteristics observed in wild-type cells: a tightly polarized phenotype and the ability to track moving pheromone input\, in comparison with the corresponding deterministic model. \nExisting models of cell polarization have focused solely on the biochemical signaling system. However\, there exists a well-known interplay between the growth of the mating projection and the mechanical forces of the cell wall in determining the shape of the cell. The cell wall of S. cerevisiae both defines its shape and provides the mechanical integrity necessary to sustain the large internal turgor pressure. Under the isotropic push of turgor pressure\, polarized expansion occurs via localized assembly of new cell wall material in combination with a simultaneous softening of the cell wall\, inducing it to yield and locally expand. Intracellular signaling directs enzymes with the ability to modify cross-linking of polymers in the cell wall to the region of polarization. The resulting mechanical feedback from the wall expansion initiates the delivery of raw material via vesicular transport. \nTo accurately model this complex biological phenomena\, we have developed a multiscale computational framework for simulating the coupling of the stochastic dynamics of biochemical reactions involved in shaping walled cells to the mechanical processes of cell wall expansion and growth. Our computational method exploits the time-scale separation between the relatively slow dynamics of the cell wall and the rapid interactions of the intercellular signaling network. URL:https://seasevents.nmsdev7.com/event/meam-seminar-cell-polarization-and-growth/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Mechanical Engineering and Applied Mechanics":MAILTO:meam@seas.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200213T150000 DTEND;TZID=America/New_York:20200213T160000 DTSTAMP:20260408T031828 CREATED:20200211T212333Z LAST-MODIFIED:20200211T212333Z UID:10006406-1581606000-1581609600@seasevents.nmsdev7.com SUMMARY:CIS Seminar: “User Generated Content: Opportunities to Inform Healthcare” DESCRIPTION:Abstract \nWhen individuals post to social media or use wearable devices\, data generated through these everyday interactions with technology reveal a great deal about behaviors that influence health in ways that were previously not observable. In my work\, I seek to leverage this data to characterize and measure the naturalistic manifestations a.k.a digital phenotyping of mental and physical health. \nIn this talk\, we will look at a) uncovering linguistic markers of ADHD using self-declared statuses on Twitter\, b) scaling language-based user-level questionnaire-estimated psychological stress predictions to communities\, and c) forecasting healthcare utilization as documented in the medical records of a sample of patients using their Facebook posts. Across these studies\, I argue that user generated data is a source of collateral information that can augment clinical practice and potentially guide interventions. URL:https://seasevents.nmsdev7.com/event/cis-seminar-user-generated-content-opportunities-to-inform-healthcare/ LOCATION:Wu and Chen Auditorium (Room 101)\, Levine Hall\, 3330 Walnut Street\, Philadelphia\, PA\, 19104\, United States ORGANIZER;CN="Computer and Information Science":MAILTO:cherylh@cis.upenn.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20200213T120000 DTEND;TZID=America/New_York:20200213T130000 DTSTAMP:20260408T031828 CREATED:20200109T164002Z LAST-MODIFIED:20200109T164002Z UID:10006368-1581595200-1581598800@seasevents.nmsdev7.com SUMMARY:BE Seminar: "Repurposing bacterial two-component systems as sensors for synthetic biology applications " DESCRIPTION:Two-component systems (TCSs) are the largest family of signal transduction pathways in biology\, and a treasure trove of biosensors for engineering applications. Though present in plants and other eukaryotes\, TCSs are ubiquitous in bacteria. Bacteria use TCSs to sense everything from metal ions to carbohydrates and light\, and activate responses such as biofilm formation\, antibiotic-resistance\, and virulence. Despite their importance\, the vast majority of TCSs remain uncharacterized. The major challenges are that most bacteria cannot be cultured nor genetically manipulated in the laboratory\, and that many TCSs are silenced by poorly-understood gene regulatory networks in laboratory conditions. We have recently developed synthetic biology technologies to address these challenges. In particular\, we have developed dual inducible promoter systems that allow us simultaneously express both TCS proteins to optimal levels in the model Gram-negative and Gram-positive bacteria E. coli and B. subtilis. In addition\, we have developed a method to modularly interchange the DNA-binding domains of response regulator proteins\, enabling unknown or silent TCS output promoters to be replaced with well-characterized alternatives. Finally\, we have developed a method to rationally tune the amount of input signal required to activate a TCS over several orders of magnitude by introducing mutations that specifically alter the intrinsic phosphatase activity of the sensor histidine kinase protein. Using these methods\, we have repurposed cyanobacterial TCSs to function as optogenetic tools with wavelength specificities from the ultraviolet (380 nm) to the near infrared (770 nm)\, engineered gut bacteria that diagnose colon inflammation in mice\, and discovered a novel pH-sensing TCS in the genome of Yersinia pestis\, the causative agent of bubonic plague. Additionally\, we have constructed a library of >500 uncharacterized TCSs from the human gut microbiome\, which we are screening for novel sensors of gut metabolites and diseases in humans. Finally\, we are using our methods to develop new anti-virulence compounds that inhibit TCSs that regulate pathogenesis in major human pathogens. Our work is accelerating fundamental microbiological discoveries and has broad applications in synthetic biology. URL:https://seasevents.nmsdev7.com/event/be-seminar-title-tbc-4/ LOCATION:Room 337\, Towne Building\, 220 South 33rd Street\, Philadelphia\, PA\, 19104\, United States CATEGORIES:Seminar ORGANIZER;CN="Bioengineering":MAILTO:be@seas.upenn.edu END:VEVENT END:VCALENDAR