CBE Doctoral Dissertation Defense: “Context-Dependent Protein Surface Hydrophilicity” (Lilia F. Escobedo)
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Vagelos Institute for Energy Science and Technology, Room 121
231 S 34th Street, Philadelphia, PA, United States
Abstract: Proteins perform many important biological functions while also avoiding fouling in an aqueous and crowded cellular environment. Their surfaces have evolved to be both chemically heterogeneous (containing nonpolar, polar, and charged groups) as well as hydrophilic. While nonpolar groups are known to induce hydrophobicity, surface heterogeneity has been found to enhance hydrophilicity and the […]


