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    • BE Grace Hopper Lecture: Powering tumor cell migration through heterogeneous microenvironments

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    Glandt Forum, Singh Center for Nanotechnology 3205 Walnut Street, Philadelphia, PA, United States

    To move through tissues, cancer cells must navigate a complex, heterogeneous network of fibers in the extracellular matrix.  This network of fibers also provides chemical, structural and mechanical cues to the resident cells.  In this talk, I will describe my lab’s efforts to understand the forces driving cell movements in the tumor microenvironment.  Combining tissue […]

    The Joy of Being Faculty: How to Apply for a Faculty Position

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    Heilmeier Hall (Room 100), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

    This professional development workshop is designed to provide Penn Engineering graduate students and postdocs with a richer understanding of what it is like to pursue a career in academia from those that have navigated the process successfully. Deputy Dean Kathleen J. Stebe (SEAS) will lead this extemporaneous panel discussions with a mix of both tenured […]

    MEAM Seminar: “Integrating Manufacturing and Topological Optimization for the Design of Architected Materials and Components”

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    Topology optimization has long been touted as a powerful tool capable of discovering innovative solutions to engineering design problems. It has been used to design 'structures' characterized at a range of length scales, from tens of microns (material architectures) to decameters (structures), for performance properties governed by a range of physics. Despite its tremendous potential […]

    CIS Seminar: “Towards a New Synthesis of Reasoning and Learning”

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    This talk discusses the role of logical reasoning in statistical machine learning. While their unification has been a long-standing and crucial open problem, automated reasoning and machine learning are still disparate fields within artificial intelligence. I will describe recent progress towards their synthesis in three facets. I start with a very practical question: how can […]

    2019 Heilmeier Lecture: “Cell-Matrix Interactions in Cancer and Fibrosis: Multiscale Chemo-Mechanical Models”

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    Cell invasion into the surrounding matrix from nonvascularized primary tumors is the main mechanism by which cancer cells migrate to nearby blood vessels and metastasize to eventually form secondary tumors. This process is mediated by an intricate coupling between intracellular forces and extracellular forces that depend on the stiffness of the surrounding stroma and the […]

    CIS Seminar: ” Deep Learning for Network Biomedicine”

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    Abstract: Large datasets are being generated that can transform biology and medicine. New machine learning methods are necessary to unlock these data and open doors for scientific discoveries. In this talk, I will argue that, in order to advance science, machine learning models should not be trained in the context of one particular dataset. Instead, […]

    The Joy of Being Faculty: How I Devised My Research Program

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    Heilmeier Hall (Room 100), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

    This professional development workshop is designed to provide Penn Engineering graduate students and postdocs with a richer understanding of what it is like to pursue a career in academia from those that have navigated the process successfully. Deputy Dean Kathleen J. Stebe (SEAS) will lead this extemporaneous panel discussions with a mix of both tenured […]

    MEAM Seminar: “Wrinkles, Spaghetti, and Knots”

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    Buckling, twisting and fracture are ubiquitous phenomena that, despite having been studied for centuries, still pose many interesting conceptual and practical challenges. In this talk, I will summarize recent theoretical and experimental work that aims to understand the role of curvature and torsion in wrinkle pattern selection, fragmentation cascades and knots. First, we will show […]

    MEAM/MSE Special Seminar: “Scalable Functional Phase Change Materials for Displays and Photonic Non-von Neumann Computing”

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    Reading Room, LRSM 3231 Walnut Street, Philadelphia, PA, United States

    In electronics, doping silicon results in one of the most versatile functional materials ever employed. The pursuit of such functional materials in the optical domain is an area of great interest in the photonics community. I hope to convince you that whatever route photonics takes, a class of materials known as phase change materials, will […]