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    • MEAM Seminar: “Lymphocyte Mechano-regulation for Immunotherapies”

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    In the dynamic field of biomedical engineering and immunotherapy, my recent research unveils the intricate relationship between mechanical forces and immune cell activation, bridging the realms of biology and immunotherapy. This study aims to unearth innovative pathways for adoptive immunotherapies, emphasizing the role of biomedical and mechanobiological insights in broadening our understanding. The core focus […]

    ESE Spring Seminar – “Learning and controlling noisy quantum systems”

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    Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

    Two of the main challenges in scaling up quantum systems are noise and control, arising from the systems' sensitivity to the environment and its exponential complexity. The first step in resolving these challenges is characterizing and learning the noisy dynamics. In this talk, I'll discuss how the very quantum features that contribute to this complexity, […]

    CIS Seminar: “Modern Clouds: Side-Channel Attacks and Defenses”

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    Cloud computing, which has seen significant growth over the past decade, fundamentally relies on the sharing of hardware resources among users. This approach enhances resource utilization and reduces operational costs. However, it also enables unintended information leakage through hardware side channels. Despite the threat of side-channel attacks, cloud vendors remain skeptical about the practicality of […]

    ASSET Seminar: “Making Machine Learning Predictably Reliable” (Andrew Ilyas, Massachusetts Institute of Technology)

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    Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

    ABSTRACT:  Despite ML models' impressive performance, training and deploying them is currently a somewhat messy endeavor. But does it have to be? In this talk, I overview my work on making ML “predictably reliable”---enabling developers to know when their models will work, when they will fail, and why. To begin, we use a case study […]

    Spring 2024 GRASP SFI: Joseph DelPreto, Massachusetts Institute of Technology, “Using Sensing and AI to Enrich Human Interactions with Machines and Nature”

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    Levine 307 3330 Walnut Street, Philadelphia, PA, United States

    This will be a hybrid event with in-person attendance in Levine 307 and virtual attendance on Zoom. ABSTRACT Coupling advanced wearable and environmental sensors with dynamic AI frameworks has the potential to transform how we engage with machines and with the natural world.  By co-developing intelligent sensors and deployable machine learning pipelines, we can unlock […]

    BE Doctoral Dissertation Defense: “Ionizable Lipid Nanoparticles for Solid Tumor Chimeric Antigen Receptor Immunotherapy” (Alvin Mukalel)

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    Auditorium, LRSM Building 3231 Walnut Street, Philadelphia, PA, United States

    The Department of Bioengineering at the University of Pennsylvania and Dr. Michael J. Mitchell are pleased to announce the Doctoral Dissertation Defense of Alvin Mukalel.     Title: Ionizable Lipid Nanoparticles for Solid Tumor Chimeric Antigen Receptor Immunotherapy Date: March 13, 2024 Time: 3:00 PM Location: LRSM Auditorium   The public is welcome to attend.

    CBE Seminar: “Carbon Capture and Utilization in Flowing Oceanwater: A New Frontier in Photocatalysis” (Shu Hu, Yale)

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    Abstract: Carbon capture, utilization, and storage (CCUS) are critical for managing anthropogenic carbon dioxide (CO2) emissions. Great strides have been made in electrification so far, but there are a handful of scenarios that still require hydrocarbon fuels and chemicals, such as aviation, long-haul trucking, and marine shipping. On the one hand, atmospheric CO2 is only […]

    Energy Week Lecture – “Towards Sustainable Artificial Intelligence and Datacenters”

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    Towne 337

    As the impact of artificial intelligence (AI) continues to proliferate, computer architects must assess and mitigate its environmental impact. This talk will survey strategies for reducing the carbon footprint of AI computation and datacenter infrastructure, drawing on data and experiences from industrial, hyperscale systems. First, we analyze the embodied and operational carbon implications of super-linear […]

    CIS Seminar: “Frameworks for Efficient Algorithms for Learning: Robustness and Data Compression”

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    Though modern machine learning has been highly successful, as we move towards more critical applications, many challenges towards building trustworthy systems, such as ensuring robustness, privacy, and fairness, arise. Ad hoc and empirical approaches have often led to unintended consequences for these objectives, thus necessitating a principled approach. Traditional solutions often require redesigning entire pipelines […]

    BE Doctoral Dissertation Defense: “Engineering Small Protein Based Inhibitors and Biodegraders for Cytosolic Delivery and Targeting of the Undruggable Proteome” (Alex Chan)

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    Smilow Center for Translational Research in SCTR 11-146AB

    The Department of Bioengineering at the University of Pennsylvania and Dr. Andrew Tsourkas are pleased to announce the Doctoral Dissertation Defense of Alex Chan Title: Engineering Small Protein Based Inhibitors and Biodegraders for Cytosolic Delivery and Targeting of the Undruggable Proteome Date: Friday, March 15 Time: 10:00-11:00 AM Location: Smilow Translational Research Center SCTR 11-146AB Zoom Link: https://upenn.zoom.us/j/94191357504 Meeting […]

    ESE Spring Seminar – “The Next Leap in Hardware Systems: Powered by Heterogenous Memory, Logic, and 3D Integration”

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    Towne 337

    Computing is at a critical juncture. Applications such as AI/ML demand much larger memory, higher bandwidth, and lower-energy compute compared to business as usual. New hardware systems, powered by heterogenous memory, logic, and 3D integration, are required for large energy efficiency, throughput, and scaleup benefits. I will present my contributions to three such heterogeneous systems: […]

    MEAM Seminar: “Designing Heart Valves from First Principles: Model Generation, Congenital Disease and Surgical Treatment”

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    Congenital heart defects affect approximately one in every hundred births and are the leading cause of infant mortality in the United States. Despite successes in surgical treatment, suboptimal outcomes remain common. Surgical treatment of complex, rare congenital heart valve defects typically follows an empirical, retrospective, “guess and check” approach. Further, children with congenital valve defects […]