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    • PICS Colloquium: “The Virtual Pregnancy: Using Computational Models to Probe Human Reproduction”

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    PICS Conference Room 534 - A Wing , 5th Floor 3401 Walnut Street, Philadelphia, PA, United States

      Preterm birth affects approximately ten percent of pregnancies and rates of maternal mortality in the US are rising. Computational investigations of pregnancy have great potential to explore fundamental aspects of reproductive physiology that are otherwise difficult or even impossible to investigate in humans. There are few-to-no good animal models of human pregnancy, and the […]

    MEAM Seminar: “Insect Respiratory Biomechanics and Insect-inspired Microfluidics”

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    Insect respiration is characterized by the rapid transport of respiratory gases within the organism and efficient exchange with the external environment. This unique system is comprised of a network of tracheal tubes that directly supply oxygen to the cells throughout the body, eliminating the need for blood as an intermediate oxygen carrier. The remarkable diversity […]

    MEAM Ph.D. Thesis Defense: “Multi-Scale Probing of Colloidal Sedimentation Dynamics in Active Suspensions”

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    Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

    Microorganisms, although challenging to observe, are ubiquitous in both natural ecosystems and industries. They inhabit diverse environments: natural ones ranging from small river tributaries and lakes to oceans, as well as in industrial settings, like wastewater treatment plants and food manufacturing. In these diverse contexts, microorganisms coexist with settling particles, a process heavily influenced by […]

    ASSET Seminar: “The Road to Explainable AI v2.0” (Eric Wong, Penn)

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    Levine 307 3330 Walnut Street, Philadelphia, PA, United States

    ABSTRACT: "A.I. has an explainability crisis"---Fortune Magazine. If you ask an ML researcher about explainability, you'll find that there are a large number of interpretability methods with no clear consensus on what to use. In fact, it isn't clear what many of these explanations even mean, let alone how they can be used. I will […]

    CBE Doctoral Dissertation Defense: “Molecular Mechanisms of Spatiotemporal Gene Control in Early Embryonic Development”

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    Towne 225

    Development of a newly fertilized embryo is a dynamic, complex, and highly coordinated process that requires precise genetic regulation and control. As the embryo develops, DNA regulatory elements known as enhancers drive gene expression patterns in specific regions of an organism at a particular time. Mis-regulation of gene expression due to mutations in enhancers can […]

    Fall 2023 GRASP SFI: David Lentink, University of Groningen, “Avian Inspired Design”

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    Levine 307 3330 Walnut Street, Philadelphia, PA, United States

    This is a hybrid event with in-person attendance in Levine 307 and virtual attendance on Zoom. This week's speaker will be virtual.  ABSTRACT My lab focusses on understanding every aspect of bird flight to improve flying robots—because birds fly further, longer, and more reliable in complex visual and wind environments. I use a multidisciplinary lens […]

    CBE Seminar: “Facile Synthesis of Polymeric Nanomaterials via Chemical Vapor Deposition Techniques” (Yang, Cornell)

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    Polymer is often considered one of the most prevalent materials in the modern age. While it has been predominantly synthesized in solution and processed into a variety of macroscopic sizes and shapes, the need for programmability in materials’ microscopic properties has challenged the traditional synthesis approaches. Recent advances in vacuum-based synthesis technologies, such as the […]

    MSE Seminar: “DumoLab Research: Regenerative Architecture with Biomaterials” Weitzman School of Design – University of Pennsylvania

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    Wu and Chen Auditorium (Room 101), Levine Hall 3330 Walnut Street, Philadelphia, PA, United States

    Dr. Mogas-Soldevila will give an overview on her DumoLab research at the Weitzman School of Design at Penn. Her works focuses on regenerative material practices bridging science, engineering, and the arts. DumoLab builds scholarship for materials design critique, and translates biomedical materials used in implants, drug delivery, and tissue scaffolding, into robust materials for use […]

    ESE PhD Thesis Defense: “Toward High-performance Simple Models of Legged Locomotion”

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    Raisler Lounge (Room 225), Towne Building 220 South 33rd Street, Philadelphia, PA, United States

    This thesis addresses the challenges of model-based planning and control in legged locomotion, particularly the trade-off between computational speed and robot performance presented by different levels of model complexities. Full-order models, while rich in detail, are often too computationally demanding for real time planning, whereas conventional reduced-order models (ROMs) tend to oversimplify the dynamics, limiting […]

    BE Doctoral Dissertation Defense: “Pooled tagging of endogenous proteins for exploration of the human proteome driven by prime editing”

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    Colket Translational Research Building (Room 4040)

    The Department of Bioengineering at the University of Pennsylvania and Dr. Ophir Shalem are pleased to announce the Doctoral Dissertation Defense of Henry Sanchez.   Title: Pooled tagging of endogenous proteins for exploration of the human proteome driven by prime editing Date: September 21, 2023 Time: 3:00pm Location: Colket Translational Research Building (Room 4040) The public is welcome to attend.

    BE Seminar: “Engineering the cell-matrix interface – understanding and guiding cell function” (Claudia Loebel, University of Michigan)

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    216 Moore Building

    The native extracellular microenvironment dynamically remodels as cells synthesize, assemble, and remodel their surroundings during tissue development, injury, and repair. In my research group, we use engineered systems to both probe mechanisms of cell-extracellular matrix (ECM) interactions (e.g., mechanobiology) and to guide cell function towards therapeutic behaviors (e.g., tissue repair/regeneration). In this seminar, I will […]