Precision engineering stands at the forefront of catalyzing transformative advancements in health and medicine. Among various precise techniques utilizing phototactic, electric, and magnetic mechanisms, acoustic devices have captured heightened attention for their capability to facilitate contactless, label-free, and biocompatible manipulation of cells, extracellular vesicles, and organisms. Demonstrating proficiency in manipulating micro/nano-objects across a diverse spectrum, acoustic platforms have evolved to facilitate cell patterning, separation, and sorting for single-cell analysis, isolate extracellular vesicles for diagnosing cancer and neurodegenerative diseases, and assemble single cells for tissue engineering. As acoustic research and technologies continue to advance, acoustic devices emerge as a linchpin, seamlessly bridging the realms of engineering and medicine. This integration propels the frontier of personalized medicine and advanced manufacturing, showcasing the transformative potential of precision engineering in shaping the future of healthcare.

In this presentation, I will explore the dynamic application of acoustics to advance precision engineering in health and medicine, spanning a range from nanometer to millimeter scales. I will showcase a series of noteworthy examples, including (1) the assembly and dynamic control of colloids, droplets, and living cells; (2) the precise separation of extracellular vesicles for disease diagnostics; and (3) the engineering of 3D tissues for therapeutic purposes. The distinctive attributes of acoustic platforms, such as precision, biocompatibility, and versatility, endow them with immense potential to serve as pioneering technologies, translating innovations in mechanical engineering into advancements in materials, biology, and medicine. Additionally, I will touch upon my past and ongoing endeavors, covering topics such as sensors and actuators, nanofabrication, and advanced packaging, showcasing broad applications in the fields of semiconductors, micro/nanorobotics, and biodevices.